Polarization Extension for LSMs
Feb 2012PicoQuant GmbHRequest Info
PicoQuant GmbH has released a polarization extension for its upgrade kit for confocal laser scanning microscopes (LSMs). Previously, commercially available upgraded LSMs could perform time-resolved fluorescence measurements, but with the new extension, upgraded microscopes also can perform polarization measurements. The extension permits access to single-molecule dynamics such as fluorescence anisotropy and polarization-resolved fluorescence correlation spectroscopy. Applications include the study of membrane dynamics, molecular rotation and orientation, molecule aggregation and cluster formation. Static anisotropy can be calculated via the newest release of the proprietary fluorescence lifetime imaging and correlation software SymPhoTime. The extension is directly mounted to the scan head of the confocal microscope. It is adaptable to the following microscopes: Olympus FluoView FV300 and FV1000; and Zeiss LSM 510, 710 and 780.