Request InfoNikon Instruments Inc.The new Ti-diSPIM module from Nikon Instruments Inc. gives light-sheet imaging capabilities to the company’s flagship Ti inverted research microscope. Selective plane illumination microscopy (SPIM) minimizes phototoxicity and photobleaching in imaging of live specimens. A thin sheet of light is used to illuminate a focal plane of the cell that is coincident with the focus of the imaging lens. This also provides optical sectioning by not illuminating out-of-focus regions, which would normally result in image blur. The module integrates Applied Scientific Instrument’s...See full productRelated content from Photonics MediaPRODUCTSPromoted Content January 2023 IssueSingle-Objective Light SheetThe single-objective light sheet geometry – known in the literature as OPM, SCAPE, SOPi, eSPIM, and SOLS – enables 4D fluorescence imaging of biological samples at high speed and low...BioPhotonics Jul/Aug 2023 IssueUpright MicroscopeThe ECLIPSE Ni-L upright microscope from Nikon Corp. features LED illumination that closely resembles natural light. The device enables accurate display of specimen colors, making it effective...BioPhotonics Nov/Dec 2023 IssueSmart Imaging SystemThe ECLIPSE Ji from Nikon is a digital inverted microscope and smart imaging system which utilizes AI to automate the acquisition and analysis of cellular images, streamlining research workflows...BioPhotonics Sep/Oct 2023 IssueOptical Stereo MicroscopesThe third-generation range of Mantis ergonomic optical stereo microscopes from Vision Engineering Ltd. feature improved optics for hand-to-eye coordination and depth perception. The microscopes...ARTICLESPhotonics.com 9/9/2022Jenoptik Breaks Ground on Dresden Fab: Week in Brief: 09/09/2022II-VI announced its corporate name change. The company, which finalized its acquisition of Coherent Inc. this summer, is now called Coherent Corp. The company also debuted a brand identity, which...BioPhotonics Nov/Dec 2023 IssueIlluminating the Unseen: Data at Depth with Light-Sheet Fluorescence MicroscopyLight-sheet fluorescence microscopy, also called single plane illumination microscopy (SPIM) is a noninvasive 3D imaging method that employs a sheet of light to illuminate a thin plane of a specimen....Photonics Spectra March 2024 IssueLaser Light Sheet Offers Insight into Snowflake AccelerationA winter wonderland calls to mind piles of fluffy, glistening snow. But to reach the ground, snowflakes are swept into the turbulent atmosphere, swirling through the air instead of plummeting...BioPhotonics Jan/Feb 2024 IssueMicroscopy Method Detects Treatment-Resistant CancerTherapy-induced senescent (TIS) cells are cancer cells that become resistant to therapies and enter a dormant stage. These cells can emerge from dormancy and induce tumor resistance and relapse. To...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookMachine Vision Cameras: Making the Right SelectionTechnological advances have resulted in new, higher-quality sensors that enable machine vision cameras to deliver greater features and functionality at a lower cost than ever before. These factors...WHITEPAPERSPhotonics.com 2/7/2024Dual Selective Plane Illumination Microscopy for Cleared Tissuect-dSPIM is a flexible and easy-to-use implementation of Selective Plane Illumination Microscopy (SPIM) that allows for dual views (d) of large samples such as cleared tissue (ct). It is one of many...Photonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 2/21/2024Dual Inverted Selective Plane Illumination MicroscopeAn overview of diSPIMPhotonics.com 10/19/2023Clean, New Bioenergy Sources: One Molecule at a TimeResearchers at Penn State University are spearheading a multidisciplinary research effort to explore ways to produce bioethanol more efficiently from lignocellulose. Importantly, this is not corn...WEBINARSPhotonics.com 10/25/2018Shareable Advanced Light-Sheet Microscopy Using FlamingoThis webinar will discuss a new model for advanced microscopy, based on shareable, modular instruments. This model, called Flamingo, is designed to bridge the gap between biology and technology....Photonics.com 10/29/2014Imaging Biology at High Spatiotemporal ResolutionJoin us for a FREE webinar Wednesday, Oct. 29, 2014, 1 p.m. EST Presenter Dr. Hari Shroff will discuss efforts to develop high-resolution optical methods better suited than conventional imaging...Photonics.com 2/16/2017High-Speed Imaging At and Beyond the Diffraction LimitHari Shroff, Ph.D., head of the Section on High Resolution Optical Imaging at the National Institute of Biomedical Imaging and Bioengineering (NIBIB), will speak on his lab's latest work to develop...Photonics.com 10/25/2022Multiorgan COVID-19 Autopsy Findings Using 3D Virtual HistologyThe study of tissue samples from the organs of individuals who have died as a direct result of acute COVID-19 infection, or its consequences, is vital to our understanding of the pathogenesis of this...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionarylight sheet fluorescence microscopyAlso known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...Photonics Dictionaryparticle image velocimetryA whole-flow-field technique providing instantaneous velocity vector measurements in a cross-section of a flow that is seeded with micron-sized particles. CCD or CMOS cameras and laser light sheets...Photonics DictionarymetalensA metalens, short for "metasurface lens," is a type of optical lens that uses nanostructured materials to manipulate light at a subwavelength scale. Unlike traditional lenses made of glass or other...Photonics DictionaryoleophobicOleophobic is a term used to describe substances or materials that repel or resist oils. The word oleophobic comes from the Greek words "oleo," meaning oil, and "phobos," meaning fear. Oleophobic...VIDEOSPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 10/12/2021pco - Frequency Domain Fluorescence Lifetime Imaging Microscopy - A Hands-On SessionThis hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...PHOTONICS BUYERS' GUIDE CATEGORIESOptical CoatingsOptical coatings are thin layers of materials applied to optical components, such as lenses, mirrors, filters, and prisms, to modify their reflective and transmissive properties. These coatings are...Custom Lapping and Polishing ServicesCustom lapping and polishing services involve specialized processes used to improve the surface finish and dimensional accuracy of components to meet specific requirements or standards. These...Optical Abrasives--CoatedTripled YAG LasersCOMPANIESPhotonics Buyers' GuideUniversal Photonics Inc.“Name the application, we have solutions,” is more than a slogan. It’s what keeps Universal Photonics a world-leader in critical surface preparation material, processing machinery...Photonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideApplied Scientific Instrumentation Inc.Applied Scientific Instrumentation, Inc. (ASI) is a company committed to the advancement of science. Our engineers and technicians have years of experience in aiding researchers with their technical...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...