Request InfoLeica Microsystems GmbHA new system from Leica Microsystems facilitates correlative light and electron microscopy (CLEM). The EM Cryo CLEM system consists of the company’s DM6000 FS fluorescence light microscope with a cryogenic stage, cryo objective and a cryo transfer shuttle, as well as the first commercially available cryo CLEM objective to enable localizing of fluorescent-labeled target structures. The HCX PL APO 50× / 0,90 objective enables researchers to define fluorescent-labeled target structures up to 100 nm in size. It is apochromatically corrected and has an NA of 0.9. Its...See full productRelated content from Photonics MediaPRODUCTSPromoted Content March 2024 IssueUltra-Precision Microscopy DemoThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...Promoted Content November 2023 IssueNucleus™ Automated MicroscopesThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...Promoted Content February 2024 IssueOEM-Ready Microscope SubsystemsThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...Promoted Content April 2024 IssueGet More Data: Automate Your MicroscopeZaber offers a selection of standard and customized motorized microscope stage products. They offer: Exceptional Performance Maximize your throughput and consistency with up to 500-nm...ARTICLESPhotonics.com 5/12/2022X-Ray Laser Achieves Its Final, Colder-Than-Space TemperatureThe superconducting particle accelerator, an upgrade to the Linac Coherent Light Source (LCLS) x-ray free-electron laser at the U.S. Department of Energy’s SLAC National Accelerator Laboratory,...BioPhotonics Sep/Oct 2022 IssueHigh-Throughput Imaging Links Microbial Metabolism With Cell IdentityAn imaging platform for investigating microbiomes in medical and environmental samples can perform high-throughput metabolism and identity analyses with single-cell resolution. Called SRS-FISH, or...BioPhotonics May/Jun 2023 IssueSuperresolution Captures Conformational Changes in ProteinsResearchers led by Nobel laureate Stefan Hell at the Max Planck Institute for Medical Research have developed a superresolution microscope with a spatiotemporal precision of 1 nm/ms. The work builds...BioPhotonics May/Jun 2023 IssueModule Uses Single-photon Microscopy to Track Cellular ActivityBrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookDetectors: Guideposts on the Road to SelectionAny number of medical, industrial, and analytical applications requires the detection of light. Chemiluminescence, bioluminescence, fluorescence, and atomic absorption are just a few, and all require...WHITEPAPERSPhotonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 1/10/2024Laser Light Engine Output StabilityIn this white paper, Dr. Iain Johnson, Lumencor’s Director of Technical Support, tests Lumencor’s laser-based CELESTA Light Engine for consistency, power, and stability using continuous wave...Photonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...Photonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...WEBINARSPhotonics.com 6/11/2015Biophotonic Imaging for Medicine: A Digital ConferenceResearchers from around the world presented their latest work at “Biophotonic Imaging for Medicine: A Digital Conference.” Presentations focused on a range of light-based imaging and...Photonics.com 7/30/2014From Product to Profit: The Powerful Impact of Early-stage, User-Based ResearchAdditional Q&A - Q: How can I distribute my questionnaire? If I am in the early stage of designing a specific product for India and I know my target audience... How can I reach them? Do you...Photonics.com 9/26/2023The Past, Present, and Future of Optical FiberHair-thin strands of glass, intrinsically transparent and strong, connect today’s world in ways that were unimaginable even 20 years ago. Over the past 50 years, glass optical fibers have...Photonics.com 6/30/2021European Photonics Manufacturing Services Funded by ECThis event is supported by the European initiatives presented and is moderated by EPIC, the European Photonics Industry Consortium. The European Commission is helping companies access the...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryfocal plane assemblyAn infrared imaging device composed of a detector array and readout electronics. It may include a cryogenic cooling system. The assemblies are used in meteorological and surveillance satellites,...Photonics DictionarycryospectroscopyThe spectrographic analysis of matter that is in a cooled state. Generally, a mechanical refrigerator is used to lower the temperature of the sample, allowing isolation and study of the sample and...Photonics DictionarycryostatA device used to maintain near-absolute temperatures for experimental procedures.Photonics Dictionarycold fingerA cryogenically cooled component incorporated into the Dewar of an infrared detector assembly to maintain the sensing elements at the proper temperature (77 K or colder).VIDEOSPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 1/9/2024CELESTA Light Engine - Customer Success StorySolving MERFISH challenges for Spatial TranscriptomicsPhotonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 10/12/2021pco - Frequency Domain Fluorescence Lifetime Imaging Microscopy - A Hands-On SessionThis hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".PHOTONICS BUYERS' GUIDE CATEGORIESClosed-Cycle Cryogenic CoolersCryogenic DewarsStirling Cycle CoolersCryopumpsAcryopump is a vacuum pump in which pressure is reduced by condensing gases on surfaces cryogenically cooled to about 20 K (liquid hydrogen) or 4 K (liquid helium).COMPANIESPhotonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideSmarAct Inc.Since 2005, SmarAct develops piezo-based, high-performance positioners and measurement tools for the micro- and nanometer scale. Positioning systems with numerous degrees of freedom and parallel...Photonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...