Request InfoPicoQuant GmbHThe combination of atomic force microscopy (AFM) with time-resolved single-molecule-sensitive fluorescence microscopy in a single instrument opens up new avenues for fascinating investigations into the structure, dynamics, and interactions of single molecules or their assemblies in cells or tissue samples. The time-resolved microscopy platform MicroTime 200 from PicoQuant can be interfaced with a series of AFMs from Bruker, JPK, and Asylum Research while maintaining its full range of capabilities, such as super-resolution via Stimulated Emission Depletion (STED) or performing Fluorescence...See full productRelated content from Photonics MediaPRODUCTSPromoted Content October 2022 IssueXYZ Nanopositioners for MicroscopyThe Nano-LPS and Nano-LPQ are ultra-low profile 3-axis nanopositioning systems with sub-nanometer precision under closed loop control. These piezo nanopositioners incorporate our exclusive PicoQ®...Promoted Content March 2023 IssueMad City Labs GmbH - Tools for the NanoscaleMad City Labs provides tools for the nanoscale for applications in photonics, microscopy, and physics. Our portfolio includes closed loop piezo nanopositioners, micropositioners, atomic force...Promoted Content June 2023 IssueNanopositioning for High-Res MicroscopyPI's new Fast Focus Stages and Multi-Axis Piezo Flexure Scanners for Microscopy are designed to improve the performance of high-resolution microscopy. Choice of piezo and voice coil motors....Photonics Spectra January 2023 IssueMicroscopy SoftwareThe Enersight software platform from Leica Microsystems is designed for microscope inspection and quality control. It allows users of any level to intuitively acquire images during inspection....ARTICLESPhotonics.com 3/14/2023Graphene Properties Add Axial Resolution Precision to 3D ImagingResearchers at the Ludwig Maximilian University of Munich (LMU) combined pulsed-interleaved MINFLUX (pMINFLUX) nanoscopy with a newly developed method for axial resolution that exploits the special...Photonics.com 2/23/2024SPAD Elevates Spatiotemporal Resolution in Conventional MicroscopesImage scanning microscopy (ISM), a superresolution technique enabled by the advent of fast and compact detector arrays, provides signal-to-noise ratio (SNR), optical sectioning, and spatial...BioPhotonics.com April 2024 IssueMicroprism-Mediated Calcium Imaging Reveals Neural Dynamics Over TimeAn approach to deep brain imaging developed at the University of Washington uses microprisms to provide stable tracking of neuronal activity over a large field of view. According to the research...Photonics.com 2/7/2024Bruker Makes Fourth and Fifth Acquisitions of 2024In separate transactions, Bruker has acquired preclinical in-vivo optical imaging systems company Spectral Instruments Imaging (SII), and Nanophoton Corporation, a provider of advanced research Raman...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookCamera Resolution: Combining Detector and Optics PerformanceCamera resolution depends upon the optical blur diameter and the detector size. Schade combined these to create an equivalent resolution that is a function of Fλ/d where F is the focal ratio,...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...WHITEPAPERSPhotonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 11/21/2023Conceptualizing Super-Resolution Microscopy eBookA clever way to overcome the limitation caused by diffraction is to use 'pointillism strategy', a concept introduced by Rainer Heintzmann in 2005. The idea is to have only one fluorescent emitter...Photonics.com 10/19/2023Clean, New Bioenergy Sources: One Molecule at a TimeResearchers at Penn State University are spearheading a multidisciplinary research effort to explore ways to produce bioethanol more efficiently from lignocellulose. Importantly, this is not corn...Photonics.com 2/28/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.WEBINARSPhotonics.com 1/24/2019Advances in Rapid 3D Imaging of Large Tissue SamplesThis webinar will discuss rapid 3D, multiplexed imaging of large tissue samples, based on recent advances in light-sheet fluorescence microscopy, multiplexed molecular labeling, and optical tissue...Photonics.com 1/21/2021Rapid and Effective Large-Area Raman Imaging: Raman Microscopy EvolvesThe last 25 years have seen Raman microscopy evolve from a relatively slow spectroscopic imaging technique, which could take days to image a sample, to an accepted rapid and powerful technique. It is...Photonics.com 1/21/2021Correlative 3D Raman Imaging: The Sample Characterization MultitoolConfocal Raman imaging is a powerful, versatile, and increasingly common microscopy technique capable of quickly identifying the molecules in a sample and visualizing their physical distribution...Photonics.com 10/14/2021Raman Imaging for the Complete Polymer Lifecycle: From Materials Science to Environmental ImpactPolymers are omnipresent in contemporary products such as coatings and packaging. They begin as chemical formulations optimized for specific functions, are produced at-scale while being checked for...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryoptical tweezersOptical tweezers refer to a scientific instrument that uses the pressure of laser light to trap and manipulate microscopic objects, such as particles or biological cells, in three dimensions. This...Photonics Dictionaryintensified charge-coupled device cameraAn intensified charge-coupled device (ICCD) camera is an advanced imaging device that combines the capabilities of both an image intensifier and a charge-coupled device (CCD) sensor to achieve...Photonics Dictionarystochastic optical reconstruction microscopyStochastic optical reconstruction microscopy (STORM) is a superresolution microscopy technique that enables imaging of biological specimens at resolutions beyond the diffraction limit of conventional...Photonics DictionarysuperresolutionSuperresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of...VIDEOSPhotonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...Photonics.com 11/20/2023Tell Your Story Even Better With Imaris - Andor TechnologyExplore every dimension and see every side of the story with Imaris - the world's most comprehensive microscopy image analysis software.Photonics.com 1/9/2024CELESTA Light Engine - Customer Success StorySolving MERFISH challenges for Spatial TranscriptomicsPHOTONICS BUYERS' GUIDE CATEGORIESMicroscopy NanotechnologyAtomic Force MicroscopesAn atomic-force microscope is a type of microscope that produces a quantitative, three-dimensional image of the surface of a sample. The surface is scanned by an extremely sharp tip mounted to a...Scanning Probe MicroscopesForensic MicroscopesCOMPANIESPhotonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideBruker Nano SurfacesBruker Nano Surfaces is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis. We cover...Photonics Buyers' GuideArkwright Technologies Pty. Ltd.Arkwright Technologies design and manufacture application specific fiber Bragg grating (FBG) sensors. Our innovative, award winning designs have evolved from over 30 years direct expertise in the...