Request InfoMad City Labs Inc.Mad City Labs’ RM21™ Microscopes are ideal for researchers who need flexible and configurable microscopes. RM21™ microscopes are suitable for super resolution microscopy, nanoscopy, TIRF microscopy, fluorescence imaging, single molecule FRET, and Colocalization Single Molecule Spectroscopy (CoSMoS). The RM21™ microscope features our high precision piezo nanopositioning, direct optical pathway access, and precision orthogonal alignment with optical table compatibility. Our nanopositioners feature proprietary PicoQ® sensors for high stability and low noise...See full productRelated content from Photonics MediaPRODUCTSPromoted Content October 2022 IssueXYZ Nanopositioners for MicroscopyThe Nano-LPS and Nano-LPQ are ultra-low profile 3-axis nanopositioning systems with sub-nanometer precision under closed loop control. These piezo nanopositioners incorporate our exclusive PicoQ®...Promoted Content March 2023 IssueMad City Labs GmbH - Tools for the NanoscaleMad City Labs provides tools for the nanoscale for applications in photonics, microscopy, and physics. Our portfolio includes closed loop piezo nanopositioners, micropositioners, atomic force...Promoted Content September 2023 IssueTools for the NanoscaleMad City Labs provides tools for the nanoscale for applications in photonics, microscopy and physics applications. Our portfolio includes closed loop piezo nanopositioners, micropositioners, atomic...Promoted Content June 2023 IssueNanopositioning for High-Res MicroscopyPI's new Fast Focus Stages and Multi-Axis Piezo Flexure Scanners for Microscopy are designed to improve the performance of high-resolution microscopy. Choice of piezo and voice coil motors....ARTICLESBioPhotonics Sep/Oct 2022 IssueSignal Sorting Method Suppresses Noise in STED MicroscopyResearchers from Zhejiang University have proposed a novel microscopy method that selectively and effectively suppresses background noise in the existing technique of stimulated emission depletion...BioPhotonics Sep/Oct 2023 IssueBrain Imaging, Image Reconstruction Combine in a Single WorkflowScientists at Institute of Science and Technology Austria (ISTA) have developed an imaging technology to analyze live brain tissue at a scope and spatial resolution that, according to the...Photonics.com 3/14/2023Graphene Properties Add Axial Resolution Precision to 3D ImagingResearchers at the Ludwig Maximilian University of Munich (LMU) combined pulsed-interleaved MINFLUX (pMINFLUX) nanoscopy with a newly developed method for axial resolution that exploits the special...Photonics.com 10/13/2022Imaging System Speeds Diagnosis with Real-Time Biopsy AnalysisResults of a pilot study conducted at the University of Rochester showed that a system based on two-photon fluorescence microscopy (TPFM) enabled rapid diagnosis of nonmelanoma skin cancer through...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookNSOM: Discovering New WorldsNSOM is suitable for studies on the mesoscopic scale (several tens to hundreds of molecular dimensions). It has become an important tool in research and applications of semiconductors, organic layers...Photonics HandbookNanopositioning: A Step AheadBy its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...WHITEPAPERSPhotonics.com 9/12/2022Ingenuity + Instrumentation: Creating a Novel 4D Microscopy MethodTracking particles at the micro or nanoscale is inherently difficult due to the complexity of the systems studied, as well as the technical challenges: a blend of instrument design, photonics,...Photonics.com 10/19/2023Clean, New Bioenergy Sources: One Molecule at a TimeResearchers at Penn State University are spearheading a multidisciplinary research effort to explore ways to produce bioethanol more efficiently from lignocellulose. Importantly, this is not corn...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 10/19/2022Positioning at the Nanoscale (and Below): Trust in Proven PerformanceThrough a deep knowledge of sensing technologies, technically adept personnel, and experience across applications as diverse as astronomy to live cell imaging, Mad City Labs helps our customers...WEBINARSPhotonics.com 1/24/2019Advances in Rapid 3D Imaging of Large Tissue SamplesThis webinar will discuss rapid 3D, multiplexed imaging of large tissue samples, based on recent advances in light-sheet fluorescence microscopy, multiplexed molecular labeling, and optical tissue...Photonics.com 5/10/2022Expanding Implementation of Fast Optimization Technology for Photonics, Optics, and Quantum Manufacturing ApplicationsAlignment time is the largest contributor to the cost of silicon photonics and optical assemblies. New industrial automation technology dramatically shortens the time required to optimally align...Photonics.com 6/5/2013Computational Microscopy, Sensing and Diagnostics for Telemedicine and Global Health ApplicationsAdditional Questions and Answers from the Webinar are below: With more than 6 billion cell phone users in the world, the majority of them in developing countries, there are opportunities for...Photonics.com 7/1/2015Optical Tools for Mapping and Fixing Complex Biological SystemsComplex biological systems like the brain present a challenge: their molecular building blocks are organized with nanoscale precision, but support physiological processes and computations that occur...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionarytotal internal reflection fluorescenceTotal internal reflection fluorescence (TIRF) microscopy is an advanced fluorescence microscopy technique that leverages the principle of total internal reflection to selectively illuminate and image...Photonics Dictionarypiezoelectric motion systemsPiezoelectric motion systems are mechanical systems that utilize piezoelectric materials to generate controlled motion or displacement. Piezoelectric materials exhibit the piezoelectric effect, which...Photonics DictionarySTED microscopySTED microscopy, or stimulated emission depletion microscopy, is a super-resolution imaging technique in fluorescence microscopy that surpasses the diffraction limit, enabling the visualization of...Photonics DictionarynanopositioningNanopositioning refers to the precise and controlled movement or manipulation of objects or components at the nanometer scale. This technology enables the positioning of objects with extremely high...VIDEOSPhotonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...Photonics.com 11/20/2023Tell Your Story Even Better With Imaris - Andor TechnologyExplore every dimension and see every side of the story with Imaris - the world's most comprehensive microscopy image analysis software.Photonics.com 11/20/2023Andor OEM IntegrationsCutting-edge Innovation √ Unparalleled Quality √ Designed-in Reliability √ Custom Designs √ Andor is the trusted choice for OEM integrations, supplying cameras, spectrographs,...PHOTONICS BUYERS' GUIDE CATEGORIESMicropositionersScanning Tunneling MicroscopesA scanning tunneling microscope is a high-resolution imaging instrument that can detect and measure the positions of individual atoms on the surface of a material. A very fine conductive probe is...Infrared MicroscopesAn infrared microscope is a type of microscope that uses radiation in the infrared region to illuminate objects that are opaque to visible radiation. The microscope consists of two illumination...Bioluminescence MicroscopesCOMPANIESPhotonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...Photonics Buyers' GuideSmarAct Inc.Since 2005, SmarAct develops piezo-based, high-performance positioners and measurement tools for the micro- and nanometer scale. Positioning systems with numerous degrees of freedom and parallel...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...