Search Menu
Photonics Media Photonics Marketplace Photonics Spectra BioPhotonics EuroPhotonics Vision Spectra Photonics Showcase Photonics ProdSpec Photonics Handbook

Laser TIRF

Carl Zeiss Ltd.Request Info
Facebook Twitter LinkedIn Email Comments
Imaging System
WELWYN GARDEN CITY, UK, April 2, 2009 – The Laser TIRF (total internal reflection fluorescence) 3 microscope imaging system manufactured by Carl Zeiss Ltd. enhances the ability of scientists to visualize near-cell membrane dynamic processes while maintaining optimum specimen incubation conditions. Single-molecule dynamic processes in cell-free systems also can be observed and, in combination with other techniques such as atomic force microscopy, the microscope provides a complete solution for users in the life sciences, biochemistry, molecular biology and biophysics arenas.

The flexible imaging system offers a variety of incubation options to maintain viable conditions for live-cell experiments, and the definite-focus module ensures accurate quantitative data over long time periods. The laser module may be equipped with up to four solid-state lasers, is acousto-optical tunable filter-controlled, and may be operated entirely from the AxioVision software interface.

Zeiss_TIRF-3.jpgThe TIRF slider is available in two versions: manual, or fully motorized and software-controllable. The motorized version enables a given illumination angle to be set with accuracy and speed, and the reproducible angle setting results in reproducible penetration depths for the light beam. Together with the corrected beam-path and special filter sets, the apochromatically corrected optics of the TIRF slider guarantee maximum image quality.

Acousto-optical tunable filter control and angle setting are integrated into the Fast Image Acquisition module of the AxioVision software, enabling higher-resolution images to be acquired within a given time frame.

The system builds on the attributes of the Laser TIRF, the first microscope to offer the combination of TIRF and transmitted-light contrasting techniques – such as differential interference contrast and bright-field – and to enable sequential recording of image pairs. By selectively exciting cellular fluorophores adsorbed, adhered or bound to the surface and employing conventional epifluorescence, researchers can relate surface effects to internal cellular structures.

For more information, visit:

Carl Zeiss Ltd.
PO Box 78
Woodfield Road
AL7 1LU Welwyn Garden City
Hertfordshire, UK
Apr 2009

* Message:
(requirements, questions for supplier)
Your contact information
* First Name:
* Last Name:
* Email Address:
* Company:
Address 2:
Postal Code:
* Country:
Phone #:
Fax #:

Register or login to auto-populate this form:
Login Register
* Required

When you click "Send Request", we will record and send your personal contact information to Carl Zeiss Ltd. by email so they may respond directly. You also agree that Photonics Media may contact you with information related to this inquiry, and that you have read and accept our Privacy Policy and Terms and Conditions of Use.
AOTF-controlledapochromatically corrected opticsBasic ScienceBiophotonicsCarl Zeissincubation optionsLaser TIRF 3microscope imaging systemMicroscopyphotonicsProductsreproducible angle settingvisualize processes near cell membrane

back to top
Facebook Twitter Instagram LinkedIn YouTube RSS
©2020 Photonics Media, 100 West St., Pittsfield, MA, 01201 USA, [email protected]

Photonics Media, Laurin Publishing
x We deliver – right to your inbox. Subscribe FREE to our newsletters.
Are you interested in this product?
When you click "Send Request", we will send the contact details you supply to Carl Zeiss Ltd. so they may respond to your inquiry directly.

Email Address:
Stop showing me this for the remainder of my visit
We use cookies to improve user experience and analyze our website traffic as stated in our Privacy Policy. By using this website, you agree to the use of cookies unless you have disabled them.