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Light Sheet Microscope

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Light Sheet Microscope  The Alpha3 light sheet microscope from PhaseView has been announced by Olympus Corp., combining the BX43 upright frame and optics with advanced multiview selective plane illumination technology.

The Alpha3 light sheet microscope system provides high temporal and spatial resolution of both fixed and live biological samples for 3D imaging. Optional Smart 3D scanning technology allows for fast z-stacking and perturbation-free acquisition at 75 images/s. Unlike traditional confocal technologies, which experience a drop-in brightness with increasing depth, light sheet offers a greater depth of field over the entire field of view. Owing in part to its dual illumination units, the Alpha3 can provide greater subcellular resolution without compromising the speed or excitation efficiency.

In addition to increased speed, another benefit of light sheet microscopy is reduced phototoxicity. The system’s multiview selective plane illumination, in combination with real-time laser focus sweeping technology, permits ultrathin optical sectioning for illumination homogeneity, increased axial resolution, and enhanced signal-to-noise response compared to traditional confocal techniques.

Photonics Spectra
Jun 2019

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Productslight sheet microscopyAlpha3MicroscopyPhaseViewopticsimagingAmericasEuropeOlympus

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