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Lambda Research Optics, Inc. - DFO

Optical Microscope

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Optical MicroscopeThe HT-1 novel optical microscope from Tomocube Inc. utilizes diffraction tomography to generate 3D holographic images of unlabelled live cells.

At the heart of the HT-1 is a complex digital micromirror-device optical light shaper, consisting of several hundred thousand micromirrors arranged in a rectangular array. Each individual mirror can be tilted ±12°, and the use of the digital micromirror device eliminates the need for moving parts in the light path. This patented technology allows the HT-1 to set its control beam rotation and rapidly switch its illumination angle to generate the 3D refractive index tomogram of the sample.

The microscope delivers quantitative nanoscale, real-time, dynamic images of individual living cells quickly and simply without any sample preparation. The holotomography images also deliver vital information on unique cell properties including cell volume, shapes of subcellular organelles, cytoplasmic density, surface area, and deformability. The simplicity of operation and elimination of any preparative requirement will allow more researchers and clinicians to quantitatively study cell pathophysiology and the efficacy of drug treatments.


Published: October 2018
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ProductsHT-1novel optical microscopeMicroscopytomocubeAsia-PacificOptics

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