Request InfoCoolLED Ltd.The award winning pE-300 Series is a range of LED Illumination Systems for Fluorescence, Optogenetics, Electrophysiology and high-speed microscopy applications. It comprises 3 systems providing a solution that covers a range of everyday fluorescence microscopy; from the simple pE-300lite through the classic pE-300white to the highly controllable pE-300ultra. This series of products now delivers DOUBLE the intensity at the microscope sample plane. It allows adjustment of output in 1% steps, giving precise control. The broad spectrum covers everyday fluorophores: DAPI, CFP, Aqua, FITC, TRITC,...See full productRelated content from Photonics MediaPRODUCTSPromoted Content October 2023 IssueLED Technology for OEM ApplicationsCoolLED’s Amora Series for custom microscopy illumination is based on an established portfolio of off-the-shelf products, adapted to offer unparalleled customization opportunities. This...BioPhotonics Mar/Apr 2023 IssueLED Illumination SystemsThe pE-400 series of four-wavelength LED illumination systems from CoolLED provide sophisticated control and powerful illumination for cost-effective fluorescence microscopy. The series...Promoted Content February 2024 IssueLightning-Fast LED IlluminationCoolLED's ground-breaking pE-800 Series Illumination Systems for fast, powerful, and affordable imaging is popular for high-speed live cell fluorescence — but the potential applications don't...Promoted Content June 2022 Issue8-Channel Illumination Control in SoftwareCoolLED’s ground-breaking pE-800 Series Illumination Systems for fast, powerful, and affordable imaging can now be controlled in Olympus/Evident cellSens imaging software version 4.1. This is...ARTICLESBioPhotonics Sep/Oct 2023 IssueMicroscopy Method Uses Infrared Light to Image Molecules with Vibrational ContrastThe complementary strengths of fluorescence and vibrational microscopy are combined in a new technique developed at Caltech, which is called bond-selective fluorescence-detected infrared-excited...Photonics.com 10/24/2023Fluorescence Lifetime Imaging Could Improve Cancer Surgery OutcomesExtreme precision is required to surgically remove a cancerous tumor without damaging the surrounding healthy tissue. Yet surgeons often must rely on their eyes and hands to determine where to cut....BioPhotonics Jan/Feb 2024 IssueLabel-Free Imaging Shows Dynamics of Intracellular Cargo TransportUntil now, scientists have relied on fluorescence microscopy techniques to study intracellular cargo transport, a vital process to maintaining essential cellular functions. However, the effects of...BioPhotonics.com November 2023 IssueLight-Activated Tool Controls Protein Bonds and Tracks Cell AdhesionOptical tools can be used to activate biological functions, but with current methods the effects are slow to appear, and sustained effects require continuous light activation. As a result, these...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookTunable Light Sources: A Popular Choice for Measurement ApplicationsMany common spectroscopic measurements require the coordinated operation of a detection instrument and light source, as well as data acquisition and processing. Integration of individual components...Photonics HandbookIntegrating Spheres: Collecting and Uniformly Distributing LightAn integrating sphere’s function is to spatially integrate radiant flux (light). However, before one can optimize a sphere design for a particular application, it is important to understand how...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookLight-Emitting Diodes: A PrimerThe wavelength range of commercially available LEDs with single-element output power of at least 5 mW is 275 to 950 nm. Each wavelength range is made from a specific semiconductor material family,...WHITEPAPERSPhotonics.com 6/16/2022Optical Filters and LED IlluminationUnderstanding the interplay of optical filters, microscope light source and fluorophore selection can be a complex task, especially when it comes to multi-channel imaging. However, the selection of...Photonics.com 12/2/2022FISBA READYBeam™ - Compact Powerful Laser SourceThe FISBA READYBeam™ is our answer to customers' increasing demand for compact, powerful, and reliable multicolor laser source that can be easily integrated into existing set-ups. The multicolor...Photonics.com 1/10/2024Laser Light Engine Output StabilityIn this white paper, Dr. Iain Johnson, Lumencor’s Director of Technical Support, tests Lumencor’s laser-based CELESTA Light Engine for consistency, power, and stability using continuous wave...Photonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...WEBINARSPhotonics.com 6/2/2022Advances in LED Illumination for Fluorescence ImagingLED illumination for fluorescence microscopy systems has progressed significantly from a time when LED sources had low optical power and a limited range of wavelengths. While the benefits of LED...Photonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...Photonics.com 3/28/2019Going the Extra Mile with Contrast Optimization: A Practical Comparison of Micro-Imaging System OptimizationDesigning micro-imaging systems commonly used in robotic surgery and precision small-scale imaging used in the defense, industrial, and commercial industries requires calculation of the modulation...Photonics.com 1/10/2022Photonics Spectra Conference 2022: January 10 - 13Photonics Media will host its second annual Photonics Spectra Conference Jan. 10-13. The virtual event will comprise four technology tracks — Lasers, Optics, Sensors and Detectors, and Imaging...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryoptical filterAn optical filter is a device that selectively transmits or blocks specific wavelengths, or colors, of light. Optical filters are used to control the spectral content of light in various...Photonics Dictionarydichroic mirrorA dichroic mirror, also known as a dichroic beamsplitter or interference filter beamsplitter, is an optical device that selectively reflects or transmits light based on its wavelength. Dichroic...Photonics DictionaryfluorescenceFluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of...Photonics Dictionaryultraviolet fiber opticsUltraviolet (UV) fiber optics refers to optical fibers that are designed and optimized for the transmission of ultraviolet light, which is electromagnetic radiation with wavelengths shorter than...VIDEOSPhotonics.com 1/24/2022Welcome to CoolLEDIntroducing the experts who design and manufacture high performance LED Illumination Systems.Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 9/25/2013Fluorescence Microscopy Using the TECHSPEC Cage SystemKatie Walker, a Product Line Engineer at Edmund Optics, showcases Edmund Optics' Optical Cage System and how it can be used to build a digital video fluorescence microscope. The Optical Cage System...Photonics.com 3/4/2022Lasers for Neuroscience - Toptica Photonics2-photon fluorescence microscopy has become a key technology in biological imaging in neuroscience enabling three-dimensional, noninvasive studies of the neuronal structure and activity on the...PHOTONICS BUYERS' GUIDE CATEGORIESMedical Light-Emitting Diodes (LEDs)Controlled Illumination SystemsSuperluminescent Light-Emitting Diodes (LEDs)A superluminescent light-emitting diode is an emitter based on stimulated emission with amplification but insufficient feedback for oscillation to build up.Inspection Light SourcesCOMPANIESPhotonics Buyers' GuideCoolLED Ltd.CoolLED designs and manufactures cutting edge LED illumination systems for researchers and clinicians using the latest LED technology. Since our team of four introduced the first commercially...Photonics Buyers' GuideExcelitas Technologies Corp.Excelitas Technologies® Corp. is a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions to meet the illumination, optical, optronic,...Photonics Buyers' GuideSutter Instrument CompanyIn 1977, Dale Flaming, a scientist working at the University of California at San Francisco, was having difficulty reliably producing micropipettes. He developed the first electronically controlled...Photonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...