Request InfoNikon Instruments Inc.Nikon Instruments Inc. has unveiled a controlled-light-exposure microscopy unit for the Nikon C1 confocal microscope system. The control unit uses two laser confocal imaging methods to optimize the laser excitation and detector sensitivity range, resulting in fewer photobleaching effects and less saturation of the detector signals. It calculates the fluorescent integration signal and exposure time for each pixel in real time, performs acoustic-optic modulator high-speed shutter control and high-speed operation processing based on the amount of acquired fluorescence signal and then outputs the...See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Nov/Dec 2023 IssueFLIM Camera SystemThe LIFA vTAU from Lambert Instruments is a camera-based system designed to transform fluorescence lifetime imaging microscopy (FLIM) for live cell applications. Featuring a single-photon avalanche...BioPhotonics Jan/Feb 2024 IssueLaser Scanning MicroscopesEvident’s FLUOVIEW™ FV4000 confocal laser scanning microscope and FV4000MPE multiphoton laser scanning microscope, feature advancements in imaging technology that empower researchers to...Photonics.com 7/31/2023XYZ PlatformThe H189 XYZ high-precision motorized XYZ deck from Prior Scientific Inc. is a versatile platform designed to complement the latest generation of 2P/3P/multiphoton/confocal microscopy systems. ...Photonics.com 6/29/2023Compact UV LaserThe Spectra-Physics® Vanguard™ One™ UV125 from MKS Instruments Inc. is a compact UV laser designed for bio-instrumentation applications. The laser delivers >125 mW of UV...ARTICLESPhotonics Spectra January 2024 IssueVirtual Superlens Passes Diffraction Limit Without DistortionThe diffraction limit enforces physical restrictions on how closely an object can be examined using traditional optical methods. Previous attempts to develop superlenses that image beyond the...BioPhotonics May/Jun 2023 IssueModule Uses Single-photon Microscopy to Track Cellular ActivityBrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...BioPhotonics Nov/Dec 2023 IssuePhotoacoustic Microscopy Method Delivers Higher SensitivityA multispectral, super-low-dose photoacoustic microscopy (SLD-PAM) system developed by City University of Hong Kong (CUHK) achieves significantly higher sensitivity than traditional optical...BioPhotonics Sep/Oct 2023 IssueMicroscopy Method Uses Infrared Light to Image Molecules with Vibrational ContrastThe complementary strengths of fluorescence and vibrational microscopy are combined in a new technique developed at Caltech, which is called bond-selective fluorescence-detected infrared-excited...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookDetectors: CCDs for Life-Science ApplicationsSince their invention in the late 1960s, charge-coupled devices, also called CCDs, have found widespread use in imaging applications. Electronic cameras based on CCD technology are used in...WHITEPAPERSPhotonics.com 2/21/2024Dual Inverted Selective Plane Illumination MicroscopeAn overview of diSPIMPhotonics.com 10/19/2023Clean, New Bioenergy Sources: One Molecule at a TimeResearchers at Penn State University are spearheading a multidisciplinary research effort to explore ways to produce bioethanol more efficiently from lignocellulose. Importantly, this is not corn...Photonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 9/27/2023Raman SpectroscopyTo achieve accurate and precise Raman measurements, optical filters play a crucial role in enhancing signal-to-noise ratio, and reducing background interference. This white paper explores the...WEBINARSPhotonics.com 10/25/2022KEYNOTE: Deep Learning-Enabled Computational Microscopy and Diffractive ImagingOzcan provides an overview of his recent work on using deep neural networks in advancing computational microscopy and sensing systems. He also covers the systems' biomedical applications, including...Photonics.com 10/27/2022Multiline Lasers Help Simplify Systems Based on Light-Sheet Microscopy for Clinical ApplicationsFluorescence imaging using lasers is a key technique in both biomedical research and clinical applications. Fluorescence-based microscopy for high-resolution and high-throughput multifluorophore...Photonics.com 6/5/2013Computational Microscopy, Sensing and Diagnostics for Telemedicine and Global Health ApplicationsAdditional Questions and Answers from the Webinar are below: With more than 6 billion cell phone users in the world, the majority of them in developing countries, there are opportunities for...Photonics.com 10/24/2023Speeding Up Microscopy and Image Analytics: Integrating TechniquesPairing up the capabilities of optical microscopy and computer vision is a common strategy to enhance the performance of a broad spectrum of biological and biomedical screening applications. The most...PHOTONICS DICTIONARY+ TERMSPhotonics DictionarysupercontinuumSupercontinuum refers to a broad spectrum of light that spans a wide range of wavelengths, typically from the visible to the near-infrared or even mid-infrared regions of the electromagnetic...Photonics Dictionaryx-ray phase contrast microscopyUsed for high-resolution surface study with subnanometer resolution. XRIM uses interfacial phase contrast with application of hard x-rays over elementary surface structures availing the observation...Photonics Dictionaryfiber-based confocal luminescence microscopeA microscope in which laser light is delivered through single-mode fibers that replace the pinhole usually used in confocal microscopy. When the Gaussian mode is imaged from the fiber output onto the...Photonics Dictionaryquantitative phase imagingQuantitative phase imaging (QPI) is an advanced imaging technique used in microscopy to measure and analyze the optical phase information of transparent specimens. Unlike traditional brightfield...VIDEOSPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 10/12/2021pco - Frequency Domain Fluorescence Lifetime Imaging Microscopy - A Hands-On SessionThis hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".PHOTONICS BUYERS' GUIDE CATEGORIESPicosecond LasersMedical/Biomedical Light SourcesSupercontinuum LasersMicroscope StagesA microscope stage is the component of a microscope on which the sample or slide to be examined is placed. Depending on the design of the microscope, the stage may play a passive role of just...COMPANIESPhotonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideCASTECH INC.CASTECH is a recognized leading supplier of nonlinear optical crystals, laser crystals and precision optical components for laser, telecom, medical, analysis and detector markets. Products...Photonics Buyers' GuideOptikos CorporationThe Optical Engineering Experts® Optikos designs and manufactures metrology products for measuring and assuring optical image quality; and provides optical engineering design, development,...