Leica Microsystems AG, Microscopy Div.Incorporating a microscopy technique that merges spherical waves of two objectives to produce a single round wave, the TCS 4Pi confocal microscope is available from Leica Microsystems AG. The device, suitable for measuring structures in living cells measuring 100 nm, records specimens in layers, providing 3-D stacked images that allow the user to rotate, image, view and measure the specimen from all sides. The microscope is designed to study the structures and processes within cells, as well as to reveal the dynamics and interaction of proteins within cells.See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Mar/Apr 2023 IssueConfocal MicroscopeThe Dragonfly 600 confocal microscope from Andor Technology Ltd. allows users to image live specimens for days without phototoxicity or photobleaching. The device features a total internal...Promoted Content November 2023 IssueNucleus™ Automated MicroscopesThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...BioPhotonics Mar/Apr 2024 IssueMicroplate WellsThe series of wells that have been added to ibidi’s µ-Plates include an expansion to its µ-Plate 96 Well to include both square and round shapes. The plates are available in 24, 96,...Photonics Showcase November 2023 IssueQS-PLL™ AFM ControllerThe QS-PLL™ AFM controller is designed for use with AFM resonant probes. The high sensitivity of resonant probes makes it ideal for applications such as scanning NV magnetometry and quantum...ARTICLESPhotonics.com 9/13/2022Intelligent Microscope Framework Captures Biological EventsBiophysicists at École Polytechnique Fédérale de Lausanne (EPFL) introduced a method to automate microscope control for imaging biological events in detail with the help of...BioPhotonics Mar/Apr 2023 IssueRefined Laser Systems Raises $2.9M for Rapid Cancer DiagnosticsBiophotonics technology company and University of Münster spinout Refined Laser Systems has raised €2.7 million ($2.9 million) to develop a prototype intraoperative microscope that the...Photonics.com 12/16/2022NASA Launches Lunar Flashlight: Week in Brief: 12/16/22NASA’s Lunar Flashlight has communicated with mission controllers and confirmed it is healthy after launching Dec. 11 from Cape Canaveral Space Force Station. The satellite embarked on a...Photonics Spectra April 2024 IssueShortwave System Captures Photoluminescence Lifetime in One ShotAn imaging system developed by researchers from the Institut national de la recherche scientifique (INRS) captures the photoluminescence lifetimes of rare-earth doped nanoparticles in the micro- to...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookMeasuring Surface Roughness: The Benefits of Laser Confocal MicroscopyWhen evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and...Photonics HandbookNSOM: Discovering New WorldsNSOM is suitable for studies on the mesoscopic scale (several tens to hundreds of molecular dimensions). It has become an important tool in research and applications of semiconductors, organic layers...WHITEPAPERSPhotonics.com 11/30/2022Shanghai Optics Design for Manufacturing (DFM) Case StudyShanghai Optics offers first-class Design for Manufacturing (DFM) services. We are proud of our track history helping customers improve product quality and reduce their manufacturing cost...Photonics.com 9/1/2022Precision Motion and How to Achieve ItNanoscale motion requires fastidious attention to instrumentation, passive controls, and experiment design. Most users have experience in motion control within the sphere of the microscale. In this...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 4/28/2023“Fingerprint” vs Handheld Raman Applications and the Different Optical Filters That Enable ThemRaman spectroscopy is a powerful non-invasive, non-contact tool capable of identifying molecular constituents of samples. Wavelength selective optical filters are used to block the dominant Rayleigh...WEBINARSPhotonics.com 10/23/2013Adaptive Optics for MicroscopyUpdate: Additional Questions from the Webinar Answered below. Enabling Structured Illumination Microscopy in Thick Tissue with Adaptive Optics Peter Kner University of Georgia ...Photonics.com 10/26/2021Quantum-Enhanced Superresolution Confocal MicroscopyFar-field optical microscopy beyond the Abbe diffraction limit is already a reality. Yet, while Abbe's theory was based on classical physics, quantum mechanical phenomena were only very recently used...Photonics.com 10/27/2022Laser Microbiopsy Could Provide Detailed Pathological Data with Limited Sample DamageWhile they are considered the gold standard for disease diagnosis, including cancer, tissue biopsy and histological evaluation have significant limitations. Among these limitations are a biopsy's...Photonics.com 6/30/2021European Photonics Manufacturing Services Funded by ECThis event is supported by the European initiatives presented and is moderated by EPIC, the European Photonics Industry Consortium. The European Commission is helping companies access the...PHOTONICS DICTIONARY+ TERMSPhotonics DictionarymicroscopyMicroscopy is a scientific technique that involves the use of microscopes to observe and study objects that are too small to be seen with the naked eye. Microscopes are instruments that magnify and...Photonics Dictionarylaser confocal microscopePhotonics Dictionaryepifluorescence microscopyFluorescence imaging technique in which the excitation light from the objective is directed into the sample producing emission at all angles. Light emitted into the objective is measured allowing the...Photonics DictionarybirefringenceBirefringence is an optical property of certain materials that causes them to exhibit different refractive indices for light of different polarizations. In other words, when light passes through a...VIDEOSPhotonics.com 10/12/2021pco - Frequency Domain Fluorescence Lifetime Imaging Microscopy - A Hands-On SessionThis hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...Photonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...PHOTONICS BUYERS' GUIDE CATEGORIESConfocal MicroscopesVideo MicroscopesMedical/Biomedical Light SourcesLaser Scanning MicroscopesCOMPANIESPhotonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideBruker Nano SurfacesBruker Nano Surfaces is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis. We cover...Photonics Buyers' GuideAllied Vision Technologies GmbHFor over 30 years, Allied Vision has helped people see the bigger picture to achieve their goals. We believe knowledge is power and always strive to deliver valuable insight with our technology...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...