FEI Life Sciences (acquired by Thermo Fisher)FEI has announced a suite of solutions for correlative light and electron microscopy. They bring data from different imaging techniques together automatically in minutes, giving cell biologists the precise information they need. Scientists believe that correlating information from the cellular down to the molecular level will lead to discoveries that will improve their understanding and treatment of cancer, AIDS and Parkinson’s. Electron microscopy offers resolution 1000 or more times better than light microscopy. Light microscopy offers a variety of techniques, such as...See full productRelated content from Photonics MediaPRODUCTSPhotonics Spectra July 2022 IssueFluorescence Filter SetKnight Optical LLC’s fluorescence filter set range suits the diverse needs of various fluorescence applications that demand high-quality components. Each set comprises an excitation...BioPhotonics Sep/Oct 2023 IssueUpright MicroscopeThe ECLIPSE Ui integrated microscope-based viewing system from Nikon Instruments Inc. is designed for clinical and pathological observation. The system provides a digital user experience,...BioPhotonics Sep/Oct 2022 IssueAI MicroscopeThe APEXVIEW™ APX100 All-in-One Microscope from Evident Corp. provides publication-quality images for life science research. Featuring Olympus optics, intuitive software, artificial...BioPhotonics Sep/Oct 2023 IssueMicrospectrophotometerThe 2030XL PRO™ Microspectrophotometer from CRAIC Technologies Inc. is a high-performance instrument for advanced materials analysis. The device offers advanced spectroscopic capabilities...ARTICLESPhotonics.com 10/24/2023Fluorescence Lifetime Imaging Could Improve Cancer Surgery OutcomesExtreme precision is required to surgically remove a cancerous tumor without damaging the surrounding healthy tissue. Yet surgeons often must rely on their eyes and hands to determine where to cut....BioPhotonics.com April 2024 IssueDeep Learning Model Helps Target Prostate Cancer Treatments to IndividualApproximately 250,000 men in the U.S. receive a prostate cancer diagnosis each year. While overall morbidity and mortality rates for this type of cancer are low, a subset of cases requires aggressive...BioPhotonics Nov/Dec 2022 IssueTechnique Enables In Vivo Vascular Imaging at Single-Cell ResolutionA two-photon fluorescence imaging method developed by researchers at the University of Hong Kong and the University of California, Berkeley was able to image the flow of individual blood cells at...BioPhotonics Mar/Apr 2024 IssueRaman Approach Safely Tracks Live-Cell RNA ExpressionSingle-cell RNA sequencing enables scientists to interrogate cells at extraordinary resolution and scale. However, the sequencing process destroys the cell, making it difficult to use the technique...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookDigital Still Cameras: The Changing Face of ImagingThe digital camera represents an integration of optics, mechanics and electronics consisting of three layers (Figures 1a, b and c). The top and the middle layers are printed circuit boards (PCBs),...WHITEPAPERSPhotonics.com 9/12/2022Ingenuity + Instrumentation: Creating a Novel 4D Microscopy MethodTracking particles at the micro or nanoscale is inherently difficult due to the complexity of the systems studied, as well as the technical challenges: a blend of instrument design, photonics,...Photonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 4/28/2023“Fingerprint” vs Handheld Raman Applications and the Different Optical Filters That Enable ThemRaman spectroscopy is a powerful non-invasive, non-contact tool capable of identifying molecular constituents of samples. Wavelength selective optical filters are used to block the dominant Rayleigh...Photonics.com 9/27/2023Raman SpectroscopyTo achieve accurate and precise Raman measurements, optical filters play a crucial role in enhancing signal-to-noise ratio, and reducing background interference. This white paper explores the...WEBINARSPhotonics.com 5/21/2015Silicon Photomultipliers, Single Photon Avalanche Diodes, and PMT’s – So what’s the difference anyway and why should I care?The Single Photon Avalanche Diode (SPAD) and the Silicon Photomultiplier (SiPM) are no longer just theory or for lab testing and poster presentations. Today they are being widely designed into some...Photonics.com 8/17/2022Sub-Cellular Biology at Tissue Scales with Cleared Tissue Axially Swept Light-Sheet MicroscopyLarge-scale interdisciplinary research efforts have worked to comprehensively catalog cellular architectures in health and disease. To aid in this effort, researchers have developed a scalable...Photonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...Photonics.com 6/6/2024COTS to Custom: Using Microscope Objectives in OEM ProductsDavid Biss of Optikos navigates the trade-offs that must be considered when developing the architecture of a microscope. In the vast expanse of life sciences, designing an OEM microscopy platform...PHOTONICS DICTIONARY+ TERMSPhotonics DictionarysupercontinuumSupercontinuum refers to a broad spectrum of light that spans a wide range of wavelengths, typically from the visible to the near-infrared or even mid-infrared regions of the electromagnetic...Photonics Dictionarycalcium indicatorA calcium indicator is a molecule that is sensitive to changes in calcium ion (Ca2+) concentrations in biological systems. These indicators are commonly used in various fields, including cell...Photonics Dictionarycustom opticA custom optic refers to an optical component that is designed, manufactured, and tailored to meet specific requirements or applications. These optics can include lenses, mirrors, prisms, filters, or...Photonics Dictionarytotal internal reflection fluorescenceTotal internal reflection fluorescence (TIRF) microscopy is an advanced fluorescence microscopy technique that leverages the principle of total internal reflection to selectively illuminate and image...VIDEOSPhotonics.com 1/18/2018Light Matters Extra: Taking Photonics Innovations from the Lab to the Operating Room - 01.2018In this month's Light Matters Extra, we give you an in-depth look at the relationship between researchers and scientists at the University of California Davis, and surgeons and clinicians at nearby...Photonics.com 7/19/2023Optical Design from AvantierAvantier delivers professional optical design consulting with innovative solutions by experienced engineers in custom design, analysis, modeling, and lens design. With over 50 years experience, our...Photonics.com 4/19/2022Fluorescence Filter Images - Optolong Optics Co. Ltd.Optolong Optics Co. Ltd., brand owner of Optolong, is a manufacturer of fluorescence filters and astronomy filters. We also offer other interference filters including UV filters, visible filters, and...Photonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...PHOTONICS BUYERS' GUIDE CATEGORIESTransmission Electron Microscopes (TEM)A transmission electron microscope is a type of microscope that uses magnetic lenses to transmit a beam of electrons through an object; the electrons are then focused on a fluorescent screen to form...Freeform OpticsFreeform optics refers to the design and fabrication of optical surfaces that do not follow traditional symmetric shapes, such as spheres or aspheres. Unlike standard optical components with...Information Display SystemsInfrared MicroscopesAn infrared microscope is a type of microscope that uses radiation in the infrared region to illuminate objects that are opaque to visible radiation. The microscope consists of two illumination...COMPANIESPhotonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideLaCroix Precision OpticsThe LaCroix name is synonymous with quality precision optics. Since 1947, three generations of family leadership have guided LaCroix Precision Optics to become the premier precision optics...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideOptikos CorporationThe Optical Engineering Experts® Optikos designs and manufactures metrology products for measuring and assuring optical image quality; and provides optical engineering design, development,...