Request InfoCoolLED Ltd.CoolLED has enabled high-speed and affordable imaging with its 8-channel pE-800 Series Illumination Systems and USB controlled TTL trigger boxes. The pE-800 Series Illumination Systems sees LEDs take centre stage as the widefield illumination method of choice. Versatile, simple to use, and backed by CoolLED’s world-renowned support and a generous warranty, the pE-800 Series makes next generation LED illumination accessible to all. Both the pE-800 and pE-800fura feature eight powerful and efficient LEDs for broad spectral coverage and individual channel control. While the pE-800 is ideal...See full productRelated content from Photonics MediaPRODUCTSPromoted Content June 2022 Issue8-Channel Illumination Control in SoftwareCoolLED’s ground-breaking pE-800 Series Illumination Systems for fast, powerful, and affordable imaging can now be controlled in Olympus/Evident cellSens imaging software version 4.1. This is...Promoted Content February 2024 IssueLightning-Fast LED IlluminationCoolLED's ground-breaking pE-800 Series Illumination Systems for fast, powerful, and affordable imaging is popular for high-speed live cell fluorescence — but the potential applications don't...Promoted Content May 2023 IssuePowerful LED Illumination for Every ApplicationCoolLED, a global expert in LED microscopy illumination, is helping scientists reach the full potential of their widefield fluorescence microscopy and optogenetics experiments with its broad range of...Promoted Content September 2022 IssueAward-winning Microscopy IlluminationCoolLED, a global expert in LED microscopy illumination, is helping scientists reach the full potential of their widefield fluorescence microscopy and optogenetics experiments with the popular pE-300...ARTICLESBioPhotonics Jan/Feb 2024 IssueLabel-Free Imaging Shows Dynamics of Intracellular Cargo TransportUntil now, scientists have relied on fluorescence microscopy techniques to study intracellular cargo transport, a vital process to maintaining essential cellular functions. However, the effects of...BioPhotonics.com April 2024 IssueMicroprism-Mediated Calcium Imaging Reveals Neural Dynamics Over TimeAn approach to deep brain imaging developed at the University of Washington uses microprisms to provide stable tracking of neuronal activity over a large field of view. According to the research...BioPhotonics.com November 2023 IssueLight-Activated Tool Controls Protein Bonds and Tracks Cell AdhesionOptical tools can be used to activate biological functions, but with current methods the effects are slow to appear, and sustained effects require continuous light activation. As a result, these...BioPhotonics.com December 2023 IssueResearchers Develop High-Precision Dual-Color Optogenetic Brain ProbeOptogenetics promises to manipulate brain circuitry by exciting or inhibiting neurons with different wavelengths of light. Until now, neural probes have largely been limited to single colors, only...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookQuantifying Light: Intensity, Uniformity Hold the KeyIntensity and uniformity can be described using different physical attributes, which makes interpreting requirements somewhat confusing. This article intends to provide an explanation and serve as a...Photonics HandbookColorimetry: How to Measure Color DifferencesThe use and importance of colorimetry has grown in unison with the increase of global manufacturing and processing. When plastic automotive trim produced on one continent must match a painted metal...Photonics HandbookInterferometry: Measuring with LightAn interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...WHITEPAPERSPhotonics.com 12/2/2022FISBA READYBeam™ - Compact Powerful Laser SourceThe FISBA READYBeam™ is our answer to customers' increasing demand for compact, powerful, and reliable multicolor laser source that can be easily integrated into existing set-ups. The multicolor...Photonics.com 1/10/2024Laser Light Engine Output StabilityIn this white paper, Dr. Iain Johnson, Lumencor’s Director of Technical Support, tests Lumencor’s laser-based CELESTA Light Engine for consistency, power, and stability using continuous wave...Photonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...Photonics.com 6/16/2022Optical Filters and LED IlluminationUnderstanding the interplay of optical filters, microscope light source and fluorophore selection can be a complex task, especially when it comes to multi-channel imaging. However, the selection of...WEBINARSPhotonics.com 6/2/2022Advances in LED Illumination for Fluorescence ImagingLED illumination for fluorescence microscopy systems has progressed significantly from a time when LED sources had low optical power and a limited range of wavelengths. While the benefits of LED...Photonics.com 10/18/2023Advancing and Extending the Spectral Range for Imaging in Fluorescence MicroscopyFluorescence microscopy has revolutionized life sciences by enabling researchers to study biological samples with exceptional precision. New excitation and illumination light sources and scientific...Photonics.com 9/22/2020LED Lighting for Fluorescence Microscopy: A Sustainable Illumination OptionFluorescence imaging in life sciences and microscopy applications has traditionally used mercury, metal halide, and xenon arc lamps for illumination. With advances in technology, LEDs are now able to...Photonics.com 11/5/2014Time-Lapse Imaging with Lamp and LED – Stability vs RepeatabilityJoin us for a FREE webinar: Wednesday, November 5, 2014, 2pm EST Fluorescence microscopy is a standard technique used in most laboratories around the world. With the invention of fluorescence...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionarycalcium indicatorA calcium indicator is a molecule that is sensitive to changes in calcium ion (Ca2+) concentrations in biological systems. These indicators are commonly used in various fields, including cell...Photonics Dictionarytotal internal reflection fluorescenceTotal internal reflection fluorescence (TIRF) microscopy is an advanced fluorescence microscopy technique that leverages the principle of total internal reflection to selectively illuminate and image...Photonics DictionaryoptogeneticsA discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light....Photonics Dictionaryfluorescent proteinFluorescent proteins are proteins that exhibit the property of fluorescence, which is the ability to absorb light at a specific wavelength and emit light at a longer wavelength. These proteins are...VIDEOSPhotonics.com 1/9/2024CELESTA Light Engine - Customer Success StorySolving MERFISH challenges for Spatial TranscriptomicsPhotonics.com 1/9/2024VOLTA Scanner: An Optical High-Throughput Plate Reader for Transmembrane Ion-Channel AnalysesSay goodbye to the limitations of manual patch clamp and outdated electrophysiological investigations. With the emergence of automated patch clamping (APC) nearly two decades ago, higher throughput...Photonics.com 1/30/2023The Endless Possibilities of Spectroscopy - Avantes as PartnerPhotonics.com 4/1/2022Excelitas TechnologiesExcelitas Technologies Corp. is a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions to meet the illumination, optical, optronic, imaging,...PHOTONICS BUYERS' GUIDE CATEGORIESControlled Illumination SystemsMedical Light-Emitting Diodes (LEDs)Underwater Light SourcesVisible Light-Emitting DiodesCOMPANIESPhotonics Buyers' GuideCoolLED Ltd.CoolLED designs and manufactures cutting edge LED illumination systems for researchers and clinicians using the latest LED technology. Since our team of four introduced the first commercially...Photonics Buyers' GuideExcelitas Technologies Corp.Excelitas Technologies® Corp. is a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions to meet the illumination, optical, optronic,...Photonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideEdinburgh Instruments Ltd.Founded in 1971, Edinburgh Instruments Ltd. is a global provider of sophisticated, state-of-the-art analytical instrumentation for optical spectroscopy. We design and manufacture a range of...