Request InfoCoolLED Ltd.NEW GENERATION LEDs CoolLED’s pE-300white offers intense, broad-spectrum LED illumination for imaging most common fluorescent stains. The pE-300whiteLight Source can be fitted directly to the microscope or specified with a liquid light guide. The system is a mercury-free alternative that is safer, more controllable, and repeatable than conventional high-pressure gas discharge illuminators. Spectral coverage is from the UV (DAPI excitation) to the Red region (Cy5 excitation). The system is perfect for hospital and regular research laboratory environments. Operation is by a remote...See full productRelated content from Photonics MediaPRODUCTSPromoted Content December 2022 IssueNEW 4-Wavelength LED IlluminationCoolLED has launched its new pE-400 Series Illumination Systems where sophisticated control combines with powerful illumination for cost-effective fluorescence microscopy, from routine to advanced...Promoted Content October 2023 IssueLED Technology for OEM ApplicationsCoolLED’s Amora Series for custom microscopy illumination is based on an established portfolio of off-the-shelf products, adapted to offer unparalleled customization opportunities. This...Promoted Content May 2023 IssuePowerful LED Illumination for Every ApplicationCoolLED, a global expert in LED microscopy illumination, is helping scientists reach the full potential of their widefield fluorescence microscopy and optogenetics experiments with its broad range of...Promoted Content June 2022 Issue8-Channel Illumination Control in SoftwareCoolLED’s ground-breaking pE-800 Series Illumination Systems for fast, powerful, and affordable imaging can now be controlled in Olympus/Evident cellSens imaging software version 4.1. This is...ARTICLESBioPhotonics Nov/Dec 2023 IssueLive-Cell Imaging Follows Early Signs of Mutation and DiseaseScientists are increasingly turning to live-cell imaging to track changes at the developmental stage of life, which is vital for the advancement of cellular biology, and to grow and monitor...Photonics Spectra March 2023 IssueTiO2 Boosts Efficiency, Photoluminescene of White Laser DiodesLight-scattering nano-elements, also known as nanoantennas due to their ability to harness light, are used as an optical control technology in nanophotonics. In combination with a phosphor plate, and...Photonics.com 1/5/2024Targeted Spectroscopy Can Improve Treatment of Eye DiseaseA targeted spectroscopy system developed at Zilia Inc., by a team led by professor Dominic Sauvageau from the University of Alberta, enables concurrent imaging of the eye fundus — a region at...BioPhotonics May/Jun 2023 IssueModule Uses Single-photon Microscopy to Track Cellular ActivityBrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookImaging Colorimetry: Accuracy in Display and Light Source MetrologyThe market for flat panel displays (FPDs) has undergone tremendous growth, driven mostly by increased demand for televisions, cell phones, computers, digital cameras and MP3 players. Similarly,...Photonics HandbookInterferometry: Measuring with LightAn interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...Photonics HandbookQuantifying Light: Intensity, Uniformity Hold the KeyIntensity and uniformity can be described using different physical attributes, which makes interpreting requirements somewhat confusing. This article intends to provide an explanation and serve as a...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...WHITEPAPERSPhotonics.com 1/10/2024Laser Light Engine Output StabilityIn this white paper, Dr. Iain Johnson, Lumencor’s Director of Technical Support, tests Lumencor’s laser-based CELESTA Light Engine for consistency, power, and stability using continuous wave...Photonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...Photonics.com 9/29/2023Accuracy in Optical DesignAnswering some common questions new users of optical design and analysis software have are “How accurate are the results?” or “Can I trust the results I get?” and discussing the importance of...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...WEBINARSPhotonics.com 6/2/2022Advances in LED Illumination for Fluorescence ImagingLED illumination for fluorescence microscopy systems has progressed significantly from a time when LED sources had low optical power and a limited range of wavelengths. While the benefits of LED...Photonics.com 12/1/2020What’s New in Solid-State Illumination for Optical Microscopy?Solid-state, white-light illumination is furthering the capabilities and lifetimes of analytical instruments. Life and material sciences alike benefit from performance enhancements conferred to...Photonics.com 10/18/2023Advancing and Extending the Spectral Range for Imaging in Fluorescence MicroscopyFluorescence microscopy has revolutionized life sciences by enabling researchers to study biological samples with exceptional precision. New excitation and illumination light sources and scientific...Photonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...PHOTONICS DICTIONARY+ TERMSPhotonics DictionaryphotobleachingPhotobleaching is a phenomenon in which the fluorescence of a fluorophore (a fluorescent molecule or dye) is permanently reduced or eliminated upon prolonged exposure to light. This process occurs...Photonics DictionarysuperresolutionSuperresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of...Photonics Dictionarylong-pass filterA long-pass filter is an optical filter that allows longer wavelengths of light to pass through while blocking or attenuating shorter wavelengths. These filters are designed to transmit light with a...Photonics Dictionarylight sheet fluorescence microscopyAlso known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...VIDEOSPhotonics.com 1/9/2024CELESTA Light Engine - Customer Success StorySolving MERFISH challenges for Spatial TranscriptomicsPhotonics.com 4/1/2022Excelitas TechnologiesExcelitas Technologies Corp. is a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions to meet the illumination, optical, optronic, imaging,...Photonics.com 1/9/2024VOLTA Scanner: An Optical High-Throughput Plate Reader for Transmembrane Ion-Channel AnalysesSay goodbye to the limitations of manual patch clamp and outdated electrophysiological investigations. With the emergence of automated patch clamping (APC) nearly two decades ago, higher throughput...Photonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...PHOTONICS BUYERS' GUIDE CATEGORIESMicroscope Illumination SystemsDisplay Illumination SystemsFiber Optic Illumination SystemsControlled Illumination SystemsCOMPANIESPhotonics Buyers' GuideCoolLED Ltd.CoolLED designs and manufactures cutting edge LED illumination systems for researchers and clinicians using the latest LED technology. Since our team of four introduced the first commercially...Photonics Buyers' GuideExcelitas Technologies Corp.Excelitas Technologies® Corp. is a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions to meet the illumination, optical, optronic,...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...Photonics Buyers' GuideFISBA AGFrom engineering to volume production all from one source Founded in 1957, FISBA is a global leader in the design and manufacture of high precision micro-optics and optical system solutions. We...