Request InfoCoolLED Ltd.CoolLED has launched the pE-100, a fluorescence LED source. The device offers instant on/off and 0 to 100% intensity controls. It can be used on all microscopes with an external light source port for epifluorescent or transmitted light applications. Users can select their desired wavelength from more than 20 LED wavelengths. An optional cable is available for external transistor-transistor logic trigger. The instrument features quiet operation, fast switching, active cooling and no hazardous materials.See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Mar/Apr 2023 IssueLED Illumination SystemsThe pE-400 series of four-wavelength LED illumination systems from CoolLED provide sophisticated control and powerful illumination for cost-effective fluorescence microscopy. The series...Promoted Content April 2022 IssueKeyLight™ by Phoseon TechnologyKeyLight™ delivers intense, broad-spectrum UV and visible wavelengths for a wide variety of colors between 340 nm and 760 nm. These compact light sources support 3, 4, 5, 6 or 7 channel systems...Photonics.com 4/11/2024Machine Vision SpotlightThe Z-SPOT from TPL Vision is a high-power spotlight made for machine vision applications that require focused and directional illumination such as pick-and-place, assembly inspection, and barcode...Promoted Content March 2024 IssueUltra-Precision Microscopy DemoThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...ARTICLESBioPhotonics May/Jun 2023 IssueModule Uses Single-photon Microscopy to Track Cellular ActivityBrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...Photonics.com 1/5/2024Targeted Spectroscopy Can Improve Treatment of Eye DiseaseA targeted spectroscopy system developed at Zilia Inc., by a team led by professor Dominic Sauvageau from the University of Alberta, enables concurrent imaging of the eye fundus — a region at...Photonics Spectra February 2024 IssueAlgorithm Boosts Live-Cell Imaging's CapabilitiesSuperresolution radial fluctuations (SRRF), a superresolution algorithm, works by observing fluctuations in radial symmetry throughout the frames of an image. SRRF supports live-cell, superresolution...Photonics.com 2/23/2024SPAD Elevates Spatiotemporal Resolution in Conventional MicroscopesImage scanning microscopy (ISM), a superresolution technique enabled by the advent of fast and compact detector arrays, provides signal-to-noise ratio (SNR), optical sectioning, and spatial...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookDetectors: Guideposts on the Road to SelectionAny number of medical, industrial, and analytical applications requires the detection of light. Chemiluminescence, bioluminescence, fluorescence, and atomic absorption are just a few, and all require...Photonics HandbookInterferometry: Measuring with LightAn interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...WHITEPAPERSPhotonics.com 1/10/2024Laser Light Engine Output StabilityIn this white paper, Dr. Iain Johnson, Lumencor’s Director of Technical Support, tests Lumencor’s laser-based CELESTA Light Engine for consistency, power, and stability using continuous wave...Photonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 2/28/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.WEBINARSPhotonics.com 6/2/2022Advances in LED Illumination for Fluorescence ImagingLED illumination for fluorescence microscopy systems has progressed significantly from a time when LED sources had low optical power and a limited range of wavelengths. While the benefits of LED...Photonics.com 1/13/2022LEDs: Expanding Capabilities for Live Cell ImagingThe light source of a widefield fluorescence microscope is often overlooked by scientists setting out to capture fast cellular processes with live cell imaging. But LEDs have changed the game. ...Photonics.com 1/22/2021Using LEDs to Enhance Image Quality and Cell ViabilitySince their debut over a decade ago, LEDs have had an ever increasing impact on the world of fluorescence microscopy. To appreciate this growth in popularity, Alex Gramann addresses many of the...Photonics.com 9/22/2020LED Lighting for Fluorescence Microscopy: A Sustainable Illumination OptionFluorescence imaging in life sciences and microscopy applications has traditionally used mercury, metal halide, and xenon arc lamps for illumination. With advances in technology, LEDs are now able to...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryoptical filterAn optical filter is a device that selectively transmits or blocks specific wavelengths, or colors, of light. Optical filters are used to control the spectral content of light in various...Photonics DictionaryCMOS quantitative polymerase chain reaction systemThis type of miniaturized system, referred to as CMOS qPCR, combines microfluidic technology with an ultralow-light CMOS bio-optical sensor with LEDs as the optical excitation source to achieve...Photonics Dictionarydichroic mirrorA dichroic mirror, also known as a dichroic beamsplitter or interference filter beamsplitter, is an optical device that selectively reflects or transmits light based on its wavelength. Dichroic...Photonics Dictionarywide-field fluorescence microscopyWide-field fluorescence microscopy uses either naturally occurring structures or staining with fluorescent tags that are activated by specific wavelengths of light and then emits a different...VIDEOSPhotonics.com 1/9/2024CELESTA Light Engine - Customer Success StorySolving MERFISH challenges for Spatial TranscriptomicsPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 10/16/2013UV Disinfectant & Photon Chips - LIGHT MATTERS 10.16.2013-Photons on Demand -Spinning-disk Microscope -UV Disenfectant This week on Light matters: Photons on demand enable compact optical chips, a spinning-disk microscope peers deeply into a cell, and...Photonics.com 6/12/2013"Big Bang" at CLEO 2013 - LIGHT MATTERS 06.12.2013-Time Cloaking -Virus Tagging -Big Bang Theory This week on Light Matters, host Melinda Rose reports from CLEO 2013 in San Jose, California and the set of the Big Bang Theory! She'll have reports on...PHOTONICS BUYERS' GUIDE CATEGORIESFluorescent Light SourcesA fluorescent light source is a tube containing mercury vapor and lined with a phosphor. When current is passed through the vapor the strong ultraviolet emission excites the phosphor, which emits...Fluorescence MicroscopesAtomic Fluorescence SpectrometersFluorescence Decay SystemsCOMPANIESPhotonics Buyers' GuideCoolLED Ltd.CoolLED designs and manufactures cutting edge LED illumination systems for researchers and clinicians using the latest LED technology. Since our team of four introduced the first commercially...Photonics Buyers' GuideAvantes BVAvantes has spent the last 30 years refining its mission as a trusted and innovative optical instruments and solutions source. Focused on applications and measurements, Avantes offers Spectrometers,...Photonics Buyers' GuideAvantier Inc.Avantier Inc. is an unparalleled leader in providing innovative imaging systems solutions and optical systems solutions. We offer advance precision custom optical design, optical engineering...Photonics Buyers' GuideEdinburgh Instruments Ltd.Founded in 1971, Edinburgh Instruments Ltd. is a global provider of sophisticated, state-of-the-art analytical instrumentation for optical spectroscopy. We design and manufacture a range of...