Request InfoIntelligent Imaging Innovations Inc. (3i)The Cleared Tissue LightSheet from Intelligent Imaging Innovations Inc. is a light-sheet microscope that can image whole organs at a high speed by illuminating them with structured light using high-resolution spatial light modulators. Similar to other fluorescence microscope techniques, the Cleared Tissue LightSheet uses laser light to stimulate fluorescence emission from genetically labelled tissue to form an image of the specimen. The microscope creates a finely focused sheet of light for optical sectioning, then uses the modulator to rapidly shift the thinnest portion of the sheet in...See full productRelated content from Photonics MediaPRODUCTSPhotonics.com 11/27/2019LED Hyperspectral LightingThe HSI range of LED hyperspectral lighting from EFFILUX SAS offers a tunable continuous spectrum from 400 to 900 nm, which can be easily integrated into a wide variety of lighting for machine vision...Photonics Spectra February 2020 IssueLight EngineThe ZIVA light engine from Lumencor Inc. features seven individually addressable lasers and advanced electronic control systems. The engine delivers high optical power, stability, and...Promoted Content September 2019 IssueMicroscopy for the Sustainable LabLaboratories can consume up to 40% of the energy used on research-intensive university campuses, but it turns out there are many ways we can all reduce our carbon footprint at work. In the first...BioPhotonics Jul/Aug 2020 IssueRaman MicroscopeThe LabRAM Soleil™ from HORIBA Scientific Inc. is a multimodal Raman microscope designed for UV-VIS-NIR imaging. The system features ultrafast imaging and advanced automation abilities...ARTICLESBioPhotonics May/Jun 2020 IssueCRISPR Technology to Target RNA Viruses Such as COVID-19Researchers at the New York Genome Center and New York University have developed a new kind of CRISPR screen technology to target RNA. Many CRISPR-based genetic screens can only edit or target DNA,...BioPhotonics Sep/Oct 2020 IssueNIH Researchers Speed Image Processing for Fluorescence MicroscopyAdvances in image processing techniques could reduce post-processing time for highly complex microscopic images up to several thousandfold, based on work done by a research team at the National...BioPhotonics Mar/Apr 2020 Issue2-Photon Microscopy Shows Learning Involves Various Areas of BrainTo explore how learning and memory-building take place in the brain, scientists at Johns Hopkins University School of Medicine used a laser-assisted imaging tool to monitor and measure levels of...BioPhotonics May/Jun 2020 IssueSpectroscopic Toolkit for Structural Biology Could Aid in Drug DesignA fluorescence-based imaging technique for monitoring single molecules could lead to a better understanding of how molecules are assembled, function, and interact, aiding in structure-guided drug...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookSuperresolution Microscopy: An Imaging Revolution: Despite tremendous accomplishments in recent years, superresolution microscopy is a relatively young field, and confusion exists in this domain of many abbreviations. However, this makes for captivating times as superresolution microscopy opens the door to wider imaging applications.Superresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookAspheric Lenses: Design Considerations: This first of two articles will cover design and manufacturing options for aspheres; the second will include more detail on manufacturing and testing processes. These articles will provide the tools optics designers need to tailor their designs to the appropriate manufacturing process and to optimize the cost of component fabrication.Aspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light Sources: Metal halide and LED light sources are changing the illumination landscape in microscopy. Brighter, easier to use and growing in application, they are driving new options in fluorescence, conventional bright-field and other contrast techniques.As recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookInterferometry: Measuring with Light: Long applied to optical shop testing, interferometry is now used to measure many different types of parts in a variety of applications, such as optical system performance, surface roughness, surface form, and displacement of moving surfaces.An interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...WHITEPAPERSPhotonics.com 10/3/2019Discovering Fine Neurovascular Structures in Tibial Epiphysis Using the FV3000 MicroscopeUnderstanding the vascular and neural projections to the knee joint is important for treating pain associated with knee arthropathy. With the FV3000 microscope, researchers at the Keio University...Photonics.com 7/30/2020Automation on a budget: Capturing high-speed multi-labelled events with LED illumination systemsThe light source for widefield fluorescence microscopy might seem like an unlikely enabler for high-speed live cell imaging, but the level of control that comes with LED Illumination Systems has...Photonics.com 1/14/2021Using Imaging Colorimeters to Correct OLED, MicroLED, and Other Emissive Displays for Production Efficiency and YieldsImaging colorimeters can improve OLED and microLED display production by ensuring visual quality of displays — measuring brightness and color uniformity at the pixel and subpixel level to correct...Photonics.com 6/12/20203 Lasers IN-ONE – FISBA READYBeam™ in Life SciencesThe FISBA READYBeam™ easily integrates into your set-up or instrument. Light-sheet Fluorescence Microscopy or Selective Plane Illumination (SPIM) enables high resolution imaging of large biological...WEBINARSPhotonics.com 3/24/2015Micro-Spectroscopy: Enabling Research From Novel Nano-Devices To Clinical DiagnosisMicro-spectroscopy is an ever developing modality for new and exciting research in the areas of nano-technology and bioscience. This webinar will look at modular approaches to microspectroscopy and...Photonics.com 8/4/2020An Oblique Plane Light-Sheet Microscope with 200-nm-Scale ResolutionLight-sheet fluorescence microscopy (LSFM) has generated significant interest in the biological community. Not only does it deliver light to only the in-focus portion of a specimen, decreasing the...Photonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...Photonics.com 5/19/2020Squeezing More Out of Light: Innovative Approaches to Time-Resolved Flow CytometryIn this webinar, presenter Giacomo Vacca, Ph.D., founder and president of Kinetic River, will discuss recent advances in time-resolved methods of flow cytometry and how these advances are being...PHOTONICS DICTIONARY+ TERMSEDU.photonics.com 6/30/2017second-harmonic generation microscopyA nonlinear label-free imaging technique commonly used during surgical procedures for the visualization of collagen fibers and muscle tissue (myosin) with submillimeter resolution. During the...EDU.photonics.com 3/5/2018Light Sheet Fluorescence Microscopy (LSFM)Also known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...EDU.photonics.com 3/5/2018differential interference contrast microscopyDifferential interference contrast (DIC) microscopy, sometimes called Nomarski Microscopy after the inventor Georges Nomarski, is one of several methods used to obtain microscope images of...EDU.photonics.com 6/30/2017high-content screeningAlso known as HCS, an analytical method designed to collect statistically relevant amounts of quantitative data on many parallel cell populations or processes within cells through the combination of...VIDEOSPhotonics.com 2/21/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 6/12/2017Sneak Preview: Laser World of Photonics 2017: Bridging Research & IndustryLaser World of Photonics — sponsored by Messe München International — provides a spotlight for promising newcomers, industry veterans and innovative companies. And with tens of thousands of people...Photonics.com 1/18/2018Supporting the Photonics Industry from the Laboratory - LIGHT MATTERS 01.2018On this month's episode of Light Matters, we take you to central Massachusetts as Worcester Polytechnic Institute and Quinsigamond Community College take on a comprehensive joint photonics laboratory...Photonics.com 1/18/2018Light Matters Extra: Taking Photonics Innovations from the Lab to the Operating Room - 01.2018In this month's Light Matters Extra, we give you an in-depth look at the relationship between researchers and scientists at the University of California Davis, and surgeons and clinicians at nearby...PHOTONICS BUYERS' GUIDE CATEGORIESMicroscope Illumination SystemsMedical/Biomedical Light SourcesCell Assay Imaging SystemsFluorescent Light SourcesA fluorescent light source is a tube containing mercury vapor and lined with a phosphor. When current is passed through the vapor the strong ultraviolet emission excites the phosphor, which emits...COMPANIESPhotonics Buyers' GuideAllied Vision Technologies GmbHABOUT US For 30 years, Allied Vision has helped people see the bigger picture to achieve their goals. We believe knowledge is power and always strive to deliver valuable insight with our...Photonics Buyers' GuideSutter Instrument CompanyIn 1977, Dale Flaming, a scientist working at the University of California at San Francisco, was having difficulty reliably producing micropipettes. He developed the first electronically controlled...Photonics Buyers' GuideAdmesy BVMEASURING COLOUR IN A WORLD OF LIGHT! Admesy offers a broad range of test and measurement instruments focused on colour and light measurements in inline production process environments. All...Photonics Buyers' GuideEdinburgh Instruments Ltd.Founded in 1971, Edinburgh Instruments Ltd. is a global provider of sophisticated, state-of-the-art analytical instrumentation for optical spectroscopy. We design and manufacture a range of...