Request InfoApplied Scientific Instrumentation Inc.The ct-dSPIM is a flexible and easy-to-use light sheet microscopy configuration optimized for imaging large cleared tissue samples. The sample is mounted on a motorized XYZ stage and imaged via stage scanning. Two multi-immersion or other objective lenses are held in an upright “V” geometry for light sheet illumination and detection. Acquisition speed is usually camera-limited. ASI manufactures the optomechanical elements, including the motorized stages and 2D galvos for creating and moving the light sheet. Lasers and sCMOS cameras are required to complete the system; users...See full productRelated content from Photonics MediaPRODUCTSPromoted Content April 2024 IssueLife Science Imaging SolutionsAdvanced imaging solutions for OEM instrument makers and researchers pushing the limits of microscopy in life science. Developing new diagnostic methods, tools and technologies? Contact Navitar or...Photonics.com 3/21/2024Probe MicroscopeThe INX™ 760 from VIAVI is a single, duplex, and multi-fiber probe microscope for reducing time in the construction, activation, and maintenance of complex fiber networks. Utilizing an...BioPhotonics Jul/Aug 2022 IssueMicroscopy SystemThe Lattice Lightsheet 7 microscopy system from ZEISS provides sample-preserving, long-term imaging of living cells. Equipped with the Hamamatsu ORCA-Fusion camera, the microscope now enables...Photonics.com 6/29/2023Compact UV LaserThe Spectra-Physics® Vanguard™ One™ UV125 from MKS Instruments Inc. is a compact UV laser designed for bio-instrumentation applications. The laser delivers >125 mW of UV...ARTICLESBioPhotonics Nov/Dec 2023 IssueIlluminating the Unseen: Data at Depth with Light-Sheet Fluorescence MicroscopyLight-sheet fluorescence microscopy, also called single plane illumination microscopy (SPIM) is a noninvasive 3D imaging method that employs a sheet of light to illuminate a thin plane of a specimen....BioPhotonics.com April 2024 IssueDeep Learning Model Helps Target Prostate Cancer Treatments to IndividualApproximately 250,000 men in the U.S. receive a prostate cancer diagnosis each year. While overall morbidity and mortality rates for this type of cancer are low, a subset of cases requires aggressive...Photonics.com 4/20/2022Rotating Laser Enables Faster, Longer Imaging of CellsA microscopy method developed at the University of Freiburg is able to resolve cellular-level detail without fluorescence, enabling observations 100 to 1000× longer and 10 to 100× times...Photonics Spectra January 2024 IssueChip-scale Mode-Locked Laser Charts Course for Integrated SensingResearchers from the City University of New York (CUNY) Graduate Center and the California Institute of Technology (CalTech) have shrunk a mode-locked laser (MLL) to the size of an optical chip with...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookInterferometry: Measuring with LightAn interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookMeasuring Surface Roughness: The Benefits of Laser Confocal MicroscopyWhen evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and...WHITEPAPERSPhotonics.com 1/10/2024Single-Objective Light SheetAn overview of the Single-Objective Light Sheet.Photonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 2/21/2024Dual Inverted Selective Plane Illumination MicroscopeAn overview of diSPIMPhotonics.com 10/19/2022Positioning at the Nanoscale (and Below): Trust in Proven PerformanceThrough a deep knowledge of sensing technologies, technically adept personnel, and experience across applications as diverse as astronomy to live cell imaging, Mad City Labs helps our customers...WEBINARSPhotonics.com 10/25/2022Multi-Immersion Lenses for Cleared-Tissue ImagingA simple design trick enables an objective lens to work in any dipping medium, unlike other multi-immersion objectives with limited refractive index range. Daniels describes the design trick and its...Photonics.com 5/15/2018Best Practices: How to Achieve the Most Accurate Laser Energy MeasurementsMeasuring a pulsed laser is complex. Besides power, you also need to worry about pulse energy, frequency, and pulse width (duration). If you need to measure laser pulse energies — perhaps to...Photonics.com 10/25/2018Shareable Advanced Light-Sheet Microscopy Using FlamingoThis webinar will discuss a new model for advanced microscopy, based on shareable, modular instruments. This model, called Flamingo, is designed to bridge the gap between biology and technology....Photonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionarylight sheet fluorescence microscopyAlso known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...Photonics Dictionarylateral shearing interferometerA lateral shearing interferometer is an optical device used in interferometry to measure phase differences between two beams of light. Interferometry is a technique that combines and analyzes...Photonics Dictionaryfiber laserA fiber laser is a type of laser in which the active gain medium is an optical fiber doped with rare-earth ions such as erbium, ytterbium, or neodymium. Fiber lasers generate coherent light through...Photonics DictionarybrightfieldBrightfield refers to a type of microscopy and imaging technique in which the specimen is illuminated with a white light source, and the image is observed or captured against a bright background. In...VIDEOSPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...Photonics.com 11/20/2023Andor OEM IntegrationsCutting-edge Innovation √ Unparalleled Quality √ Designed-in Reliability √ Custom Designs √ Andor is the trusted choice for OEM integrations, supplying cameras, spectrographs,...PHOTONICS BUYERS' GUIDE CATEGORIESStereo MicroscopesMicroscopy Immersion LiquidsGeneral Compound MicroscopesBioluminescence MicroscopesCOMPANIESPhotonics Buyers' GuideApplied Scientific Instrumentation Inc.Applied Scientific Instrumentation, Inc. (ASI) is a company committed to the advancement of science. Our engineers and technicians have years of experience in aiding researchers with their technical...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideSutter Instrument CompanyIn 1977, Dale Flaming, a scientist working at the University of California at San Francisco, was having difficulty reliably producing micropipettes. He developed the first electronically controlled...