Multi-Immersion Objectives

Advanced imaging solutions for OEM instrument makers and researchers pushing the limits of microscopy in life science. Developing new diagnostic methods, tools and technologies? Contact Navitar or...

PI’s latest breakthrough designs based on voice coil motors, ultrasonic motors, and piezo-flexure amplified actuators provide longer travel, higher dynamics, better resolution, higher guiding...

Hamamatsu’s comprehensive line of NIR and surface-enhanced Raman spectroscopic modules deliver precise results in an ultracompact form. Second to none in reliability, sensitivity, and ease of...

The P-725.1CDE1S and P-725.4CDE1S from PI are nano-focus scanner packages for applications including surface metrology, super-resolution microscopy, light sheet microscopy, and digital slide scanning...

Approximately 250,000 men in the U.S. receive a prostate cancer diagnosis each year. While overall morbidity and mortality rates for this type of cancer are low, a subset of cases requires aggressive...

Light-sheet fluorescence microscopy, also called single plane illumination microscopy (SPIM) is a noninvasive 3D imaging method that employs a sheet of light to illuminate a thin plane of a specimen....

Researchers at the Abramson Cancer Center at the University of Pennsylvania have developed a method to detect lung cancer at the cellular level in real time during biopsy. The method ensures earlier...

A limitation to conventional microscopy imaging, in which a sample is usually squeezed onto a glass slide, is that the behavior of the cells may differ from their natural environment. Further, the...

Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...

By its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...

NSOM is suitable for studies on the mesoscopic scale (several tens to hundreds of molecular dimensions). It has become an important tool in research and applications of semiconductors, organic layers...

When evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and...

This whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...

An overview of the Single-Objective Light Sheet.

To achieve accurate and precise Raman measurements, optical filters play a crucial role in enhancing signal-to-noise ratio, and reducing background interference. This white paper explores the...

Many factors affect the price of confocal microscopy systems and when purchasing a microscope, one must consider the complexity of the instrumentation and the capabilities it provides. Clearly the...

A simple design trick enables an objective lens to work in any dipping medium, unlike other multi-immersion objectives with limited refractive index range. Daniels describes the design trick and its...

Measuring a pulsed laser is complex. Besides power, you also need to worry about pulse energy, frequency, and pulse width (duration). If you need to measure laser pulse energies — perhaps to...

FREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...

This webinar will discuss rapid 3D, multiplexed imaging of large tissue samples, based on recent advances in light-sheet fluorescence microscopy, multiplexed molecular labeling, and optical tissue...

Also known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...

STED microscopy, or stimulated emission depletion microscopy, is a superresolution imaging technique in fluorescence microscopy that surpasses the diffraction limit, enabling the visualization of...

An oil immersion condenser used to permit only light that has been diffracted or dispersed by a microscope specimen to enter the microscope. It is used in dark-field microscopy.

An optical filter is a device that selectively transmits or blocks specific wavelengths, or colors, of light. Optical filters are used to control the spectral content of light in various...

Established in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...

This Software Highlight focuses on Fast Mapping in our Ramacle software. Fast Mapping enables the user to acquire Raman maps with significantly reduced acquisition times via more efficient stage...

The Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...

Explore every dimension and see every side of the story with Imaris - the world's most comprehensive microscopy image analysis software.

Applied Scientific Instrumentation, Inc. (ASI) is a company committed to the advancement of science. Our engineers and technicians have years of experience in aiding researchers with their technical...

For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...

Andor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...

Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...