Request InfoApplied Scientific Instrumentation Inc.The RM-1250 XY stage is the culmination of designing and manufacturing automated XY stages for demanding customers. A flat top, flat bottom, and multiple mounting configurations make it easy for laboratories and manufacturers to integrate it into existing systems. No detail went unexamined in the design of the RM-1250 Gen II. Linear encoder options are mounted inside the bearings, as close as possible to the sample for optimized accuracy. The RM-1250 has a higher load capacity due to its rigid body construction and intelligent bearing placement. Ultra-hard, wear-resistant coatings on...See full productRelated content from Photonics MediaPRODUCTSPromoted Content July 2021 IssueSmartStage™ XYWith a SmartStage™ XY positioner, the high-performance controller and all hardware to position the stage are built-in. By embedding what used to be multiple cables and external electronics, the...BioPhotonics Sep/Oct 2021 IssueMicropatterned SlidesMicropatterned µ-Slides from ibidi GmbH are designed for precisely controlled cell adhesion. µ-Patterning technology uses defined adhesion spots that are surrounded by a nonadhesive...Promoted Content March 2021 IssueLED Illuminators for ‘Green’ LabsCoolLED, a global expert in LED microscopy illumination, is helping labs become more sustainable by reducing the environmental impact of its popular pE-300 Series Illumination Systems, which is...Photonics Spectra March 2021 IssueLaser MicroscopeThe LEXT™ OLS5100 Laser Microscope from Olympus Corp. provides high levels of accuracy and precision for sub-μm 3D observation and surface roughness measurement in materials science. ...ARTICLESPhotonics.com 8/18/2020Photocatalyst Combination Enables Efficient Water SplittingThe breakdown of water has long been conceived as a clean way to produce hydrogen fuel, but the process has proven to be inefficient for widespread energy production in this manner. But the work of a...Photonics Spectra January 2021 IssueScientists Publish Blueprints for Cheaper Single-Molecule MicroscopeA team from the University of Sheffield has designed and built a single-molecule microscope for one-tenth the cost of commercially available models — and shared the build instructions to make...BioPhotonics Jul/Aug 2022 IssuePhotoacoustic System Enables Real-Time Neurovascular ImagingA photoacoustic imaging tool developed by Duke University researchers accommodates the need for both speed and comprehensive detail in neurovascular imaging. The imaging modality enables an approach...BioPhotonics Jan/Feb 2021 IssueResearchers Develop Open-Source Modular MicroscopeResearchers from the Leibniz Institute of Photonic Technology (Leibniz IPHT), Friedrich Schiller University, and Jena University Hospital developed a low-cost modular microscope that has the...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookLasers for Microscopy: Major Trends: In order for biologists, drug developers, clinical lab professionals and other scientists to fully exploit new microscopy techniques and applications, parallel developments in laser technology are often required. Laser manufacturers are responding with products optimized to match the needs of these applications.Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookNanopositioning: A Step Ahead: It is almost a cliché among students of creativity that innovation occurs at the intersection of fields. Since nanopositioning is a discipline that has enabled swiftly evolving application arenas as diverse as materials science, genomics, photonics, defense, biophysics, and semiconductors, it’s unsurprising that its pace of innovation is nothing short of blistering in recent years.By its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...Photonics HandbookInterferometry: Measuring with Light: Long applied to optical shop testing, interferometry is now used to measure many different types of parts in a variety of applications, such as optical system performance, surface roughness, surface form, and displacement of moving surfaces.An interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light Sources: Metal halide and LED light sources are changing the illumination landscape in microscopy. Brighter, easier to use and growing in application, they are driving new options in fluorescence, conventional bright-field and other contrast techniques.As recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...WHITEPAPERSPhotonics.com 7/28/2022Energy Transfer in a Liquid Scintillator Investigated using Time-Resolved X-ray Excited Luminescence SpectroscopyLiquid scintillator detectors are widely utilised in neutrino and astroparticle detection experiments. One liquid scintillator that is increasingly being used in large scale detection experiments is...Photonics.com 7/28/2022Sb to Mn Energy Transfer Revealed using Time-Resolved Emission Spectroscopy (TRES)Heterometallic metal halide hybrids hold great promise due to the potential for synergistic photo-physical properties depending on the choice of the constituent metal centres. In this application...Photonics.com 12/10/2021Cutting Edge Measurement of an InsertThe 3D optical profilometer S neox Five Axis makes it possible to quickly and flexibly obtain the key parameters necessary for the continuous improvement of our tools, such as the cutting edge...Photonics.com 5/17/20214 Steps to Optimize the Optics in Automated Imaging InstrumentsOptimize the performance and cost of your automated optical imaging system with 6 key equations for selecting an imaging sensor, objective lens, Z-focusing nano-positioning stage and XY sample...WEBINARSPhotonics.com 11/5/2014Time-Lapse Imaging with Lamp and LED – Stability vs RepeatabilityJoin us for a FREE webinar: Wednesday, November 5, 2014, 2pm EST Fluorescence microscopy is a standard technique used in most laboratories around the world. With the invention of fluorescence...Photonics.com 8/4/2020An Oblique Plane Light-Sheet Microscope with 200-nm-Scale ResolutionLight-sheet fluorescence microscopy (LSFM) has generated significant interest in the biological community. Not only does it deliver light to only the in-focus portion of a specimen, decreasing the...Photonics.com 1/22/2021Camera Technology in the Medical and Life Sciences 2021: Latest Developments and Upcoming TrendsThere is hardly any technology that is not constantly evolving. This is especially true for vision technology in the medical and life sciences sectors. CCD sensors have largely been discontinued, but...Photonics.com 6/9/2016Photonics for OphthalmologyPhotonics Media invites you to join us for our upcoming FREE digital conference, "Photonics for Ophthalmology." The event will feature several 15-minute online presentations on the use of light-based...PHOTONICS DICTIONARY+ TERMSEDU.photonics.com 3/5/2018two-photon excited fluorescenceTwo-photon excited fluorescence (TPEF) is a nonlinear optical method that allows imaging of biological cells and living tissue. The advantage of TPEF in comparison to conventional fluorescence...EDU.photonics.com 4/9/2018Golgi Staining TechniqueThe Golgi staining technique (also called the black reaction) makes it possible to look at the nervous system by rendering neurons visible under light microscopy. After a long process involving...EDU.photonics.com 3/5/2018holographic microscopyThe holographic recording of a microscopic specimen whereby magnification is achieved by alteration in a wavelength or radius of curvature between recording and reconstruction of the wavefront. With...EDU.photonics.com 6/25/2019quantum cascade laserA Quantum Cascade Laser (QCL) is a type of semiconductor laser that emits light in the mid- to far-infrared portion of the electromagnetic spectrum. Quantum cascade lasers offer many benefits: They...VIDEOSPhotonics.com 10/12/2021pco - Frequency Domain Fluorescence Lifetime Imaging Microscopy - A Hands-On SessionThis hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".Photonics.com 1/24/2022Welcome to CoolLEDIntroducing the experts who design and manufacture high performance LED Illumination Systems.Photonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 2/21/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...PHOTONICS BUYERS' GUIDE CATEGORIESCustom Lapping and Polishing ServicesCold MirrorsA cold mirror is a mirror whose coating serves to reflect visible radiation while transmitting the infrared.Laser Rods and Other Amplifying MaterialsA laser rod and other amplifying materials in a solid-state laser, is the material (Nd:YAG, Nd:glass, ruby) in which lasing action takes place.Optical CoatingsCOMPANIESPhotonics Buyers' GuideApplied Scientific Instrumentation Inc.Applied Scientific Instrumentation, Inc. (ASI) is a company committed to the advancement of science. Our engineers and technicians have years of experience in aiding researchers with their technical...Photonics Buyers' GuideUniversal Photonics Inc.“Name the application, we have solutions,” is more than a slogan. It’s what keeps Universal Photonics a world-leader in critical surface preparation material, processing machinery...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...Photonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...