Request InfoLeica Microsystems GmbHWETZLAR, Germany, July 26, 2010 — Resolution and contrast are important for fluorescence applications in wide-field microscopy. Undesired haze effects that reduce contrast can be minimized by using the smart principle of structured illumination. The result is fluorescence images with good contrast, high axial resolution and ultrasharp 2- and 3-D sections of the specimen. Intelligent Structured Illumination Microscopy from Leica Microsystems GmbH uses the proven OptiGrid technique. Working in harmony with the company’s high-quality optics, the aperture diaphragm integrated with the fluorescence light path also...See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Mar/Apr 2024 IssueOphthalmic MicroscopeThe Proveo 8 from Leica Microsystems is an ophthalmic microscope with an integrated EnFocus intraoperative OCT. The integration results in a 40% reduction in stack height — from 60 to 36 mm....Photonics Spectra January 2023 IssueMicroscopy SoftwareThe Enersight software platform from Leica Microsystems is designed for microscope inspection and quality control. It allows users of any level to intuitively acquire images during inspection....Photonics.com 1/31/20243D Surgical MicroscopeThe ARveo 8 from Leica Microsystems is a digital visualization microscope for neurosurgery applications. Making use of a 3D view and AR fluorescence, the microscope helps surgeons by creating clear...Photonics.com 3/18/2024MicrospectrometersThe Lightblades™ Spectrometers from CRAIC Technologies are specifically designed for microspectroscopy in research, industrial, and academic applications. Covering ultraviolet, visible, and...ARTICLESPhotonics Spectra March 2024 IssueQuantum-Inspired Method Reveals Details Hidden in NoiseResearchers at the University of Warsaw's Faculty of Physics with colleagues from Stanford University and Oklahoma State University have introduced a quantum-inspired phase-imaging method based on...Photonics.com 2/23/2024SPAD Elevates Spatiotemporal Resolution in Conventional MicroscopesImage scanning microscopy (ISM), a superresolution technique enabled by the advent of fast and compact detector arrays, provides signal-to-noise ratio (SNR), optical sectioning, and spatial...Photonics.com 2/5/2024High-Throughput Imaging Reveals Multi-Particle Cellular ActivityA new software program can map the movements of multiple particles within cells simultaneously, providing insight into cellular functions that are difficult — and sometimes impossible —...BioPhotonics May/Jun 2023 IssueModule Uses Single-photon Microscopy to Track Cellular ActivityBrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...WHITEPAPERSPhotonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...Photonics.com 1/10/2024Single-Objective Light SheetAn overview of the Single-Objective Light Sheet.WEBINARSPhotonics.com 6/5/2013Computational Microscopy, Sensing and Diagnostics for Telemedicine and Global Health ApplicationsAdditional Questions and Answers from the Webinar are below: With more than 6 billion cell phone users in the world, the majority of them in developing countries, there are opportunities for...Photonics.com 10/24/2023Vibrational Photothermal Microscopy Provides a Picture of Life in Live CellsRecently developed mid-infrared photothermal (MIP) microscopy opens a new window to look at molecules inside a living cell. In MIP microscopy, a visible beam is used to probe the local change of...Photonics.com 12/14/2011The Future of Imaging: Three PerspectivesPresenters: Professor Stephen Boppart The Future of Healthcare With Optical Biomedical Imaging A medical doctor and professor at the University of Illinois, Boppart's...Photonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionarywide-field fluorescence microscopyWide-field fluorescence microscopy uses either naturally occurring structures or staining with fluorescent tags that are activated by specific wavelengths of light and then emits a different...Photonics Dictionarylong-pass filterA long-pass filter is an optical filter that allows longer wavelengths of light to pass through while blocking or attenuating shorter wavelengths. These filters are designed to transmit light with a...Photonics Dictionaryerecting systemLenses or prisms that serve to erect the image; i.e., to bring the image upright after it has been inverted by the objective.Photonics Dictionaryfiber-linked array image formatterA wide-field multiobject spectroscopy system used in astronomy, in which a bundle of low-loss optical fibers positioned on the target images is rearranged at its other end into a linear array along...VIDEOSPhotonics.com 8/10/2021Short Introduction of CODIXX, Winner of the AURA foreign trade award 2019 - CODIXXCODIXX is a corporation under German Law, established in September 1998. After a period of research and development CODIXX started the production of a new family of dichroic glass polarizers in 2002....Photonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 2/21/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 4/19/2022Fluorescence Filter Images - Optolong Optics Co. Ltd.Optolong Optics Co. Ltd., brand owner of Optolong, is a manufacturer of fluorescence filters and astronomy filters. We also offer other interference filters including UV filters, visible filters, and...PHOTONICS BUYERS' GUIDE CATEGORIESResearch MicroscopesUltraviolet MicroscopesAn ultraviolet microscope is a microscope used either to detect selective absorption of various wavelengths by the specimen or to achieve increased resolution by virtue of the short wavelength of...Forensic MicroscopesForensic Laser SystemsCOMPANIESPhotonics Buyers' GuideShanghai Optics Inc.ISO 9001 & ISO 13485 certified and D&B DUNS # 113515303 Shanghai Optics is an unparalleled custom system solution provider offering advance precision custom optical design, engineering,...Photonics Buyers' GuideGlass Fab Inc.A History of Quality Since 1974 Glass Fab Inc. has met customers' stringent specifications by providing fabricated parts made of optical glass, filter glass, fused quartz and fused silica, low...Photonics Buyers' GuideAvantier Inc.Avantier Inc. is an unparalleled leader in providing innovative imaging systems solutions and optical systems solutions. We offer advance precision custom optical design, optical engineering...Photonics Buyers' GuideFresnel Technologies Inc.Fresnel Technologies Inc. is an expert manufacturer of molded plastic optics, including Fresnel lenses and related optical components, as well as infrared transmitting materials and optics made from...