Request InfoPicoQuant GmbHThe combination of atomic force microscopy (AFM) with time-resolved single-molecule-sensitive fluorescence microscopy in a single instrument opens up new avenues for fascinating investigations into the structure, dynamics, and interactions of single molecules or their assemblies in cells or tissue samples. The time-resolved microscopy platform MicroTime 200 from PicoQuant can be interfaced with a series of AFMs from Bruker, JPK, and Asylum Research while maintaining its full range of capabilities, such as super-resolution via Stimulated Emission Depletion (STED) or performing Fluorescence...See full productRelated content from Photonics MediaPRODUCTSPromoted Content October 2022 IssueXYZ Nanopositioners for MicroscopyThe Nano-LPS and Nano-LPQ are ultra-low profile 3-axis nanopositioning systems with sub-nanometer precision under closed loop control. These piezo nanopositioners incorporate our exclusive PicoQ®...Promoted Content March 2023 IssueMad City Labs GmbH - Tools for the NanoscaleMad City Labs provides tools for the nanoscale for applications in photonics, microscopy, and physics. Our portfolio includes closed loop piezo nanopositioners, micropositioners, atomic force...Promoted Content June 2023 IssueNanopositioning for High-Res MicroscopyPI's new Fast Focus Stages and Multi-Axis Piezo Flexure Scanners for Microscopy are designed to improve the performance of high-resolution microscopy. Choice of piezo and voice coil motors....Photonics.com 11/16/2022sCMOS CameraThe Sona-6 back-illuminated sCMOS camera from Andor Technology can be used for life science research and detection in challenging, light-starved imaging applications. The noise floor has been...ARTICLESPhotonics.com 4/20/2022Rotating Laser Enables Faster, Longer Imaging of CellsA microscopy method developed at the University of Freiburg is able to resolve cellular-level detail without fluorescence, enabling observations 100 to 1000× longer and 10 to 100× times...BioPhotonics Sep/Oct 2022 IssueA Multiphoton Microscope Enables Portable 3D Biological ImagingFor decades, optical microscopy has provided the mechanism with which to image cells and tissue for the purposes of cancer research, digital pathology, and the study of the brain. Samples are...BioPhotonics Sep/Oct 2022 IssueHigh-Throughput Imaging Links Microbial Metabolism With Cell IdentityAn imaging platform for investigating microbiomes in medical and environmental samples can perform high-throughput metabolism and identity analyses with single-cell resolution. Called SRS-FISH, or...BioPhotonics May/Jun 2023 IssueModule Uses Single-photon Microscopy to Track Cellular ActivityBrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookUltraviolet Reflectance Imaging: ApplicationsReflected-ultraviolet imaging is a rather mysterious area of the imaging field. There is relatively little actual UV imagery to be found on the Internet or in the literature compared to near-infrared...Photonics HandbookSWIR Imaging: An Industrial Processing ToolImaging has long been used in industrial processes to measure, monitor, control, or otherwise manage the production of goods. The challenge to the process designer is to develop a tool that captures...WHITEPAPERSPhotonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 10/19/2023Clean, New Bioenergy Sources: One Molecule at a TimeResearchers at Penn State University are spearheading a multidisciplinary research effort to explore ways to produce bioethanol more efficiently from lignocellulose. Importantly, this is not corn...Photonics.com 11/21/2023Conceptualizing Super-Resolution Microscopy eBookA clever way to overcome the limitation caused by diffraction is to use 'pointillism strategy', a concept introduced by Rainer Heintzmann in 2005. The idea is to have only one fluorescent emitter...Photonics.com 2/28/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.WEBINARSPhotonics.com 1/24/2019Advances in Rapid 3D Imaging of Large Tissue SamplesThis webinar will discuss rapid 3D, multiplexed imaging of large tissue samples, based on recent advances in light-sheet fluorescence microscopy, multiplexed molecular labeling, and optical tissue...Photonics.com 1/21/2021Correlative 3D Raman Imaging: The Sample Characterization MultitoolConfocal Raman imaging is a powerful, versatile, and increasingly common microscopy technique capable of quickly identifying the molecules in a sample and visualizing their physical distribution...Photonics.com 1/21/2021Rapid and Effective Large-Area Raman Imaging: Raman Microscopy EvolvesThe last 25 years have seen Raman microscopy evolve from a relatively slow spectroscopic imaging technique, which could take days to image a sample, to an accepted rapid and powerful technique. It is...Photonics.com 10/14/2021Raman Imaging for the Complete Polymer Lifecycle: From Materials Science to Environmental ImpactPolymers are omnipresent in contemporary products such as coatings and packaging. They begin as chemical formulations optimized for specific functions, are produced at-scale while being checked for...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryoptical tweezersOptical tweezers refer to a scientific instrument that uses the pressure of laser light to trap and manipulate microscopic objects, such as particles or biological cells, in three dimensions. This...Photonics Dictionaryintensified charge-coupled device cameraAn intensified charge-coupled device (ICCD) camera is an advanced imaging device that combines the capabilities of both an image intensifier and a charge-coupled device (CCD) sensor to achieve...Photonics Dictionarystochastic optical reconstruction microscopyStochastic optical reconstruction microscopy (STORM) is a superresolution microscopy technique that enables imaging of biological specimens at resolutions beyond the diffraction limit of conventional...Photonics DictionarysuperresolutionSuperresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of...VIDEOSPhotonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...Photonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...Photonics.com 10/12/2021pco - Frequency Domain Fluorescence Lifetime Imaging Microscopy - A Hands-On SessionThis hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".PHOTONICS BUYERS' GUIDE CATEGORIESAtomic Force MicroscopesAn atomic-force microscope is a type of microscope that produces a quantitative, three-dimensional image of the surface of a sample. The surface is scanned by an extremely sharp tip mounted to a...Microscopy NanotechnologyScanning Probe MicroscopesForensic MicroscopesCOMPANIESPhotonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...Photonics Buyers' GuideBruker Nano SurfacesBruker Nano Surfaces is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis. We cover...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideArkwright Technologies Pty. Ltd.Arkwright Technologies design and manufacture application specific fiber Bragg grating (FBG) sensors. Our innovative, award winning designs have evolved from over 30 years direct expertise in the...