Request InfoCoolLED Ltd.After the phenomenal popularity of the 8-channel pE-800 LED Illumination System, CoolLED took a closer look at expanding this ground-breaking technology for the calcium imaging community by swapping in a 340 and 380 nm LED. And here’s the result – a lightning-fast, 8-channel Illuminator for calcium imaging, pH monitoring, ratiometric fluorescence, FRET, optogenetics, and everyday fluorescence microscopy. Read on for an overview of what the new pE-800fura is capable of: • Fluorescence freedom: 8 powerful LEDs span 340-635 nm to cover all popular calcium and pH...See full productRelated content from Photonics MediaPRODUCTSPromoted Content October 2023 IssueLED Technology for OEM ApplicationsCoolLED’s Amora Series for custom microscopy illumination is based on an established portfolio of off-the-shelf products, adapted to offer unparalleled customization opportunities. This...Promoted Content June 2022 Issue8-Channel Illumination Control in SoftwareCoolLED’s ground-breaking pE-800 Series Illumination Systems for fast, powerful, and affordable imaging can now be controlled in Olympus/Evident cellSens imaging software version 4.1. This is...Promoted Content November 2023 IssueAutomated Fluorescence, SimplifiedCoolLED’s Amora Series for custom microscopy illumination is based on an established portfolio of off-the-shelf products, adapted to offer unparalleled customization opportunities. This...Promoted Content March 2023 IssueACT Label Certified LED IlluminatorThe CoolLED pE-400 Series Illumination Systems combine sustainability for fluorescence microscopy and optogenetics. Both the pE-400 and pE-400max Illumination Systems include four intense LEDs...ARTICLESBioPhotonics Nov/Dec 2023 IssuePhotoacoustic Microscopy Method Delivers Higher SensitivityA multispectral, super-low-dose photoacoustic microscopy (SLD-PAM) system developed by City University of Hong Kong (CUHK) achieves significantly higher sensitivity than traditional optical...BioPhotonics Jul/Aug 2023 IssueCentury-Old Effect Applied for Study of Embryonic DevelopmentResearchers have applied line-scanning Brillouin microscopy (LSBM), a microscopy technique based on Brillouin scattering, to visualize the mechanical properties of living cells over space and time,...BioPhotonics Jan/Feb 2024 IssueLabel-Free Imaging Shows Dynamics of Intracellular Cargo TransportUntil now, scientists have relied on fluorescence microscopy techniques to study intracellular cargo transport, a vital process to maintaining essential cellular functions. However, the effects of...BioPhotonics.com November 2023 IssueLight-Activated Tool Controls Protein Bonds and Tracks Cell AdhesionOptical tools can be used to activate biological functions, but with current methods the effects are slow to appear, and sustained effects require continuous light activation. As a result, these...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookColorimetry: How to Measure Color DifferencesThe use and importance of colorimetry has grown in unison with the increase of global manufacturing and processing. When plastic automotive trim produced on one continent must match a painted metal...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...WHITEPAPERSPhotonics.com 12/2/2022FISBA READYBeam™ - Compact Powerful Laser SourceThe FISBA READYBeam™ is our answer to customers' increasing demand for compact, powerful, and reliable multicolor laser source that can be easily integrated into existing set-ups. The multicolor...Photonics.com 6/16/2022Optical Filters and LED IlluminationUnderstanding the interplay of optical filters, microscope light source and fluorophore selection can be a complex task, especially when it comes to multi-channel imaging. However, the selection of...Photonics.com 9/29/2023Accuracy in Optical DesignAnswering some common questions new users of optical design and analysis software have are “How accurate are the results?” or “Can I trust the results I get?” and discussing the importance of...Photonics.com 12/15/2023Mini Size 1535-nm Eye-safe Laser Rangefinder Module for Distance SensorThe Lumispot Tech LSP-LRS-0310F is a compact and lightweight laser rangefinder module, notable for being the smallest of its kind, weighing only 33 g. It is a highly precise tool for measuring...WEBINARSPhotonics.com 6/2/2022Advances in LED Illumination for Fluorescence ImagingLED illumination for fluorescence microscopy systems has progressed significantly from a time when LED sources had low optical power and a limited range of wavelengths. While the benefits of LED...Photonics.com 10/25/2018Shareable Advanced Light-Sheet Microscopy Using FlamingoThis webinar will discuss a new model for advanced microscopy, based on shareable, modular instruments. This model, called Flamingo, is designed to bridge the gap between biology and technology....Photonics.com 1/22/2021Using LEDs to Enhance Image Quality and Cell ViabilitySince their debut over a decade ago, LEDs have had an ever increasing impact on the world of fluorescence microscopy. To appreciate this growth in popularity, Alex Gramann addresses many of the...Photonics.com 11/12/2020Optical and Electrical Microsystems for Advanced Biomedical Imaging and DiagnosisMedical diagnosis heavily depends on innovative methods for biomedical imaging. New system concepts that combine miniaturized optical MEMS components, such as scanning mirrors and spatial light...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionarylight sheet fluorescence microscopyAlso known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...Photonics DictionaryphototoxicityPhototoxicity refers to the harmful effects caused by exposure to light, particularly intense or ultraviolet (UV) light, on living cells or organisms. This phenomenon is often associated with the...Photonics Dictionaryfluorescent proteinFluorescent proteins are proteins that exhibit the property of fluorescence, which is the ability to absorb light at a specific wavelength and emit light at a longer wavelength. These proteins are...Photonics DictionaryFörster resonance energy transferFörster resonance energy transfer (FRET) is a mechanism describing the transfer of energy between two closely spaced fluorescent molecules. This phenomenon is named after the German scientist...VIDEOSPhotonics.com 2/21/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 1/30/2023The Endless Possibilities of Spectroscopy - Avantes as PartnerPhotonics.com 1/24/2022Welcome to CoolLEDIntroducing the experts who design and manufacture high performance LED Illumination Systems.Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...PHOTONICS BUYERS' GUIDE CATEGORIESControlled Illumination SystemsUnderwater Light SourcesVisible Light-Emitting DiodesMachine Vision Illumination SystemsCOMPANIESPhotonics Buyers' GuideCoolLED Ltd.CoolLED designs and manufactures cutting edge LED illumination systems for researchers and clinicians using the latest LED technology. Since our team of four introduced the first commercially...Photonics Buyers' GuideExcelitas Technologies Corp.Excelitas Technologies® Corp. is a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions to meet the illumination, optical, optronic,...Photonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideSutter Instrument CompanyIn 1977, Dale Flaming, a scientist working at the University of California at San Francisco, was having difficulty reliably producing micropipettes. He developed the first electronically controlled...