Request InfoNikon Instruments Inc.Nikon Instruments Inc. has released the N-SIM, a superresolution microscope that operates at speeds enabling the study of microstructures and nanostructures of fixed and living cells with molecular-scale resolution. Based on the Eclipse Ti inverted microscope, the instrument produces twice the resolution of conventional optical microscopes, combining structured illumination microscopy (SIM) technology – licensed to Nikon by the University of California, San Francisco – with the company’s CFI Apo total internal reflection fluorescence 100x oil objective lens that has a...See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Sep/Oct 2023 IssueUpright MicroscopeThe ECLIPSE Ui integrated microscope-based viewing system from Nikon Instruments Inc. is designed for clinical and pathological observation. The system provides a digital user experience,...Photonics.com 9/8/2022Zoom Microscope LensThe BS-1085 4K Apochromatic Monocular Zoom Microscope Lens from BestScope International Ltd. features an adopted apochromatic optical system. The ultrahigh-resolution, 4K apochromatic monocular...Photonics Spectra July 2022 IssueFluorescence Filter SetKnight Optical LLC’s fluorescence filter set range suits the diverse needs of various fluorescence applications that demand high-quality components. Each set comprises an excitation...BioPhotonics May/Jun 2023 IssueMonochrome Microscope CameraThe Digital Sight 50M monochrome microscope camera from Nikon Instruments Inc. conducts high-precision analysis and large-volume sampling for use in applications such as well plate screening. ...ARTICLESBioPhotonics.com March 2024 IssueDMD-Based SIM Attains Fast Superresolution Bioimaging in 3DAlthough structured illumination microscopy (SIM) demonstrates ultrahigh temporal and spatial resolution, the speed and intricacy of polarization modulation affect the speed and quality of its...Photonics Spectra January 2024 IssueVirtual Superlens Passes Diffraction Limit Without DistortionThe diffraction limit enforces physical restrictions on how closely an object can be examined using traditional optical methods. Previous attempts to develop superlenses that image beyond the...BioPhotonics Nov/Dec 2022 IssueExpansion Microscopy Technique Reveals Hidden NanostructuresProteins and other molecules are often tightly packed together inside a living cell. These dense clusters can be difficult to image because the fluorescent labels used to make them visible...BioPhotonics Jan/Feb 2024 IssueLabel-Free Imaging Shows Dynamics of Intracellular Cargo TransportUntil now, scientists have relied on fluorescence microscopy techniques to study intracellular cargo transport, a vital process to maintaining essential cellular functions. However, the effects of...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookCamera Resolution: Combining Detector and Optics PerformanceCamera resolution depends upon the optical blur diameter and the detector size. Schade combined these to create an equivalent resolution that is a function of Fλ/d where F is the focal ratio,...WHITEPAPERSPhotonics.com 9/12/2022Ingenuity + Instrumentation: Creating a Novel 4D Microscopy MethodTracking particles at the micro or nanoscale is inherently difficult due to the complexity of the systems studied, as well as the technical challenges: a blend of instrument design, photonics,...Photonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 9/27/2023Raman SpectroscopyTo achieve accurate and precise Raman measurements, optical filters play a crucial role in enhancing signal-to-noise ratio, and reducing background interference. This white paper explores the...Photonics.com 8/7/2023What Is the Modulation Transfer Function?The modulation transfer function, or MTF, is a parameter used to evaluate the performance of a lens. MTF provides a quantitative and standardized way to characterize optical systems, so the metric is...WEBINARSPhotonics.com 2/16/2017High-Speed Imaging At and Beyond the Diffraction LimitHari Shroff, Ph.D., head of the Section on High Resolution Optical Imaging at the National Institute of Biomedical Imaging and Bioengineering (NIBIB), will speak on his lab's latest work to develop...Photonics.com 10/23/2013Adaptive Optics for MicroscopyUpdate: Additional Questions from the Webinar Answered below. Enabling Structured Illumination Microscopy in Thick Tissue with Adaptive Optics Peter Kner University of Georgia ...Photonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...Photonics.com 10/29/2014Imaging Biology at High Spatiotemporal ResolutionJoin us for a FREE webinar Wednesday, Oct. 29, 2014, 1 p.m. EST Presenter Dr. Hari Shroff will discuss efforts to develop high-resolution optical methods better suited than conventional imaging...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionarystructured illumination microscopyStructured illumination microscopy (SIM) is an advanced optical imaging technique used in microscopy to enhance the resolution of images beyond the diffraction limit imposed by traditional light...Photonics DictionarysuperresolutionSuperresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of...Photonics DictionarymetalensA metalens, short for "metasurface lens," is a type of optical lens that uses nanostructured materials to manipulate light at a subwavelength scale. Unlike traditional lenses made of glass or other...Photonics Dictionarymeta-opticsMeta-optics, also known as metasurface optics or flat optics, is a branch of optics that involves the design, fabrication, and utilization of artificial structures called metasurfaces to control and...VIDEOSPhotonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...Photonics.com 7/19/2023Optical Design from AvantierAvantier delivers professional optical design consulting with innovative solutions by experienced engineers in custom design, analysis, modeling, and lens design. With over 50 years experience, our...Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...PHOTONICS BUYERS' GUIDE CATEGORIESSimple LensesMicroscope LensesStereoscopic CamerasOptical PelliclesCOMPANIESPhotonics Buyers' GuideFOCtek Photonics Inc.FOCtek provides customers with all types of custom manufactured lenses, Precision Optical Components, Polarizing Optics, Prisms, Filters, Coatings, Optical Systems, Crystals, Nonlinear Crystals,...Photonics Buyers' GuideLaCroix Precision OpticsThe LaCroix name is synonymous with quality precision optics. Since 1947, three generations of family leadership have guided LaCroix Precision Optics to become the premier precision optics...Photonics Buyers' GuideCASTECH INC.CASTECH is a recognized leading supplier of nonlinear optical crystals, laser crystals and precision optical components for laser, telecom, medical, analysis and detector markets. Products...Photonics Buyers' GuideShanghai Optics Inc.ISO 9001 & ISO 13485 certified and D&B DUNS # 113515303 Shanghai Optics is an unparalleled custom system solution provider offering advance precision custom optical design, engineering,...