Request InfoFor Live-Cell ResearchLeica Microsystems GmbHWETZLAR, Germany, Oct. 25, 2007 -- The new Leica TIRF (total internal reflection fluorescence) microscope system, called the Leica AM TIRF MC, allows the entire fluorescence excitation spectrum to now be used for real-time visualization of live cell dynamics, according to manufacturer Leica Microsystems GmbH. Leica's scanner sensor automatically matches the TIRF angle at all wavelengths to the required penetration depth, and positions the laser so that the TIRF penetration depth remains constant even when the wavelength is changed. 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