Request InfoMad City Labs Inc.The Nano-LPS and Nano-LPQ are ultra-low profile 3-axis nanopositioning systems with sub-nanometer precision under closed loop control. These piezo nanopositioners incorporate our exclusive PicoQ® sensor technology, ensuring high stability and low noise performance, making them ideal for single molecule microscopy, super resolution microscopy and other nanoscopy applications. These nanopositioners include the low noise Nano-Drive® controller with USB digital interface and Nano-Route®3D software for motion control. Compatible with a wide range of 3rd party control software....See full productRelated content from Photonics MediaPRODUCTSPromoted Content March 2023 IssueMad City Labs GmbH - Tools for the NanoscaleMad City Labs provides tools for the nanoscale for applications in photonics, microscopy, and physics. Our portfolio includes closed loop piezo nanopositioners, micropositioners, atomic force...Promoted Content December 2022 IssueQS-PLL™ AFM controllerThe QS-PLL™ AFM controller is designed for use with AFM resonant probes. The high sensitivity of resonant probes makes it ideal for applications such as scanning NV magnetometry and quantum...Promoted Content January 2022 IssueProspective MPX - First User-Friendly Multiphoton MicroscopeThe first completely integrated two-photon microscope with built-in (tunable) femtosecond laser Ideal for e.g. biologists, neuroscientists, etc., who want to focus on their research not on optics....Promoted Content November 2022 IssueLS850 Fully Automated MicroscopeThe powerful, new LS850 Microscope is the latest generation of our fully automated three-channel flagship model and offers the latest advances in optics, cameras, throughput, and user flexibility....ARTICLESPhotonics.com 4/20/2022Rotating Laser Enables Faster, Longer Imaging of CellsA microscopy method developed at the University of Freiburg is able to resolve cellular-level detail without fluorescence, enabling observations 100 to 1000× longer and 10 to 100× times...BioPhotonics Sep/Oct 2021 IssueSTED Microscopy Calibration Method Improves Brain ImagingResearchers from the University of Bordeaux have found a way to calibrate stimulated emission depletion (STED) microscopy for improved brain imaging. The method increases the depth at which STED...Photonics.com 6/4/2021Metamaterial Lets Light-Sheet Microscopes See in SuperresolutionA hyperbolic metamaterial developed at the University of California, San Diego enables ordinary light-sheet microscopes to observe subcellular structures — in other words, enabling an ordinary...BioPhotonics Mar/Apr 2023 IssueHydrogel Improvements Boost Utility of Expansion MicroscopyCollaborators from Carnegie Mellon University, the University of Pittsburgh, and Brown University have described a microscopy technique and set of protocols that overcome a bottleneck to the...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookMeasuring Surface Roughness: The Benefits of Laser Confocal Microscopy: 3D imaging and ultrahigh resolution are ideal for the inspection of materials with defined surface finishes and textures.When evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and...Photonics HandbookNanopositioning: A Step Ahead: It is almost a cliché among students of creativity that innovation occurs at the intersection of fields. Since nanopositioning is a discipline that has enabled swiftly evolving application arenas as diverse as materials science, genomics, photonics, defense, biophysics, and semiconductors, it’s unsurprising that its pace of innovation is nothing short of blistering in recent years.By its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...Photonics HandbookSuperresolution Microscopy: An Imaging Revolution: Despite tremendous accomplishments in recent years, superresolution microscopy is a relatively young field, and confusion exists in this domain of many abbreviations. However, this makes for captivating times as superresolution microscopy opens the door to wider imaging applications.Superresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookInterferometry: Measuring with Light: Long applied to optical shop testing, interferometry is now used to measure many different types of parts in a variety of applications, such as optical system performance, surface roughness, surface form, and displacement of moving surfaces.An interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...WHITEPAPERSPhotonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 10/19/2022Positioning at the Nanoscale (and Below): Trust in Proven PerformanceThrough a deep knowledge of sensing technologies, technically adept personnel, and experience across applications as diverse as astronomy to live cell imaging, Mad City Labs helps our customers...Photonics.com 8/5/2021Nanopositioning! What is it good for?This article explores the nuances of piezo nanopositioners, how they function, and the extent of their capability. We also examine how closed-loop feedback control can be applied to a piezo...Photonics.com 9/1/2022Precision Motion and How to Achieve ItNanoscale motion requires fastidious attention to instrumentation, passive controls, and experiment design. Most users have experience in motion control within the sphere of the microscale. In this...WEBINARSPhotonics.com 1/24/2019Advances in Rapid 3D Imaging of Large Tissue SamplesThis webinar will discuss rapid 3D, multiplexed imaging of large tissue samples, based on recent advances in light-sheet fluorescence microscopy, multiplexed molecular labeling, and optical tissue...Photonics.com 3/23/2021How the Kinetix sCMOS Camera Broke the Golden Rule of Compromise in Scientific ImagingIn this webinar, product and applications experts from Teledyne Photometrics are joined by leading imaging scientists to discuss how the latest developments in scientific CMOS (sCMOS) technology are...Photonics.com 1/13/2022How Pixel Size and MTF Affect Modern Microscopy and See the Invisible with MicroscopesMicroscope designs are moving toward larger field-of-view and larger image circles to capture more information with the recording of a single image. For that reason, camera manufacturers are...Photonics.com 6/17/2021Multi-Line Lasers or Laser Combiners: What Solution Is Best for Fluorescence Imaging?Fluorescence imaging is a key technique in both biomedical research and clinical diagnosis. Fluorescence-based microscopy for high-resolution and high-throughput multifluorophore imaging typically...PHOTONICS DICTIONARY+ TERMSEDU.photonics.com 4/10/2018single-molecule spectroscopyAn advanced technique that allows the detection of one molecule within a crystal or a cell through optical excitation. Single-molecule spectroscopy (SMS) can image at subwavelength scales, down to a...EDU.photonics.com 9/8/2009electrostrictiveA common form of high-precision, ceramic-based actuator capable of moving and measuring at the nanometer level.EDU.photonics.com 3/5/2018X-ray Phase Contrast Microscopy (XRIM)Used for high-resolution surface study with subnanometer resolution. XRIM uses interfacial phase contrast with application of hard x-rays over elementary surface structures availing the observation...EDU.photonics.com 3/5/2018fluorescence microscopyObservation of samples using excitation produced fluorescence. A sample is placed within the excitation laser and the plane of observation is scanned. Emitted photons from the sample are filtered by...VIDEOSPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 1/24/2022Welcome to CoolLEDIntroducing the experts who design and manufacture high performance LED Illumination Systems.Photonics.com 10/12/2022SL160 Slide Loader - Prior ScientificPrior Scientific is pleased to introduce its newest automated slide loader, the SL160. This 160 slide capacity loader combines reliability, easy set up, and high capacity to provide automated slide...Photonics.com 10/16/2013UV Disinfectant & Photon Chips - LIGHT MATTERS 10.16.2013-Photons on Demand -Spinning-disk Microscope -UV Disenfectant This week on Light matters: Photons on demand enable compact optical chips, a spinning-disk microscope peers deeply into a cell, and...PHOTONICS BUYERS' GUIDE CATEGORIESMicropositionersFluorescence MicroscopesScanning Tunneling MicroscopesA scanning tunneling microscope is a high-resolution imaging instrument that can detect and measure the positions of individual atoms on the surface of a material. A very fine conductive probe is...Transmission Electron Microscopes (TEM)A transmission electron microscope is a type of microscope that uses magnetic lenses to transmit a beam of electrons through an object; the electrons are then focused on a fluorescent screen to form...COMPANIESPhotonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...Photonics Buyers' GuideAndor TechnologyWe are global leaders in the development and manufacture of high performance scientific digital cameras for academic, industrial and government applications. Through continuous dialogue with our...Photonics Buyers' GuideSmarAct Inc.Since 2005, SmarAct develops piezo-based, high-performance positioners and measurement tools for the micro- and nanometer scale. Positioning systems with numerous degrees of freedom and parallel...Photonics Buyers' GuidePrior Scientific Inc.For over 100 years, Prior Scientific has been manufacturing precision optical and electro-mechanical equipment and instrumentation. Prior is a leader in the development of precision motion,...