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pco.edge Scientific CMOS Camera

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ROMULUS, Mich., Aug. 3, 2010 — The Cooke Corp. has introduced the pco.edge camera system that offers complete high-fidelity scientific imaging. Based on a scientific CMOS image sensor, it delivers low noise, fast frame rates, a wide dynamic range, high quantum efficiency (QE), high resolution and a large field of view, simultaneously and all in one image.

The camera features low readout noise of 1.4 e¯ rms. Even at the maximum speed of 100 fps at full resolution of 2560 × 2160 pixels (5.5-megapixel, 21.8-mm diagonal, 6.5-µm pixels) the readout noise is <2 e¯. Increased frame rates with smaller regions of interest (for example, 900 fps at 320 × 240 pixels) are user-selectable. In comparison to a 1.3-megapixel scientific CCD camera featuring 6 e¯ readout noise at 10 fps, the pco.edge camera at 1.3-megapixel resolution features <2 e¯ readout noise at a frame rate of 210 fps.

The low readout noise combined with the high full-well capacity of 30,000 e¯ achieves an intrascene dynamic range of better than 22,000:1, providing high dynamic 16-bit images.

Unlike electron-multiplying CCD image sensors that feature on-chip amplification to detect the lowest light levels at the expense of reduced effective QE, the camera achieves a peak QE of >55% without compromising spatial and temporal resolution, making it suitable for use in low-light conditions above two photons (zero dark current conditions).

User-selectable choice of rolling or global shutter mode for exposure provides flexibility for a variety of applications. The camera features 5 °C stabilized Peltier cooling, allowing for continuous operation free of any drift phenomena in image sequences.

Applications include live-cell microscopy, particle imaging velocimetry, single-molecule detection, super-resolution microscopy, total internal reflection fluorescence microscopy/waveguides, spinning disk confocal microscopy, genome sequencing (second- and third-generation), Förster resonance energy transfer, fluorescence recovery after photobleaching, lucky astronomy/imaging, adaptive optics, solar astronomy, fluorescence spectroscopy, bio- and chemiluminescence, high-content screening, photovoltaic inspection, x-ray tomography, ophthalmology, flow cytometry, biochip reading, machine vision, TV/broadcasting, spectral and hyperspectral imaging, and laser-induced breakdown spectroscopy.
Aug 2010

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adaptive opticsAmericasastronomyBasic Sciencebiochip readingbioluminescenceBiophotonicscamerasCCDchemiluminescenceCMOScontinuous operationCookeenergyflow cytometryfluorescence recovery after photobleachingfluorescence spectroscopyFörster resonance energy transferFRAPFRETgenome sequencingglobal shutterhigh-content screeninghyperspectral imagingimaginglaser-induced breakdown spectroscopyLIBSlive-cell microscopylow-lightlucky astronomy/imagingmachine visionMicroscopyophthalmologyparticle imaging velocimetrypco.edgePeltier coolingphotovoltaic inspectionProductsrolling shuttersecond- generationSensors & Detectorssingle-molecule detectionsolar astronomyspectral imagingspinning disk confocal microscopysuper-resolution microscopythird-generationTIRFtotal internal reflection fluorescence microscopy/waveguidesTV/broadcastingx-ray tomography

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