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Sensors & Detectors News
Fluorescence correlation spectroscopy helps clarify cell mitosis
Jun 1, 2006 — Understanding the processes at the heart of the cellular functions regulating mitosis, such as signal transduction, requires precise quantitation of the cell’s molecules. According to researcher Zifu Wang at the University of California, Irvine, the best way to achieve this is through fluorescence correlation spectroscopy. Wang and his colleagues at Irvine and at the University of California, San Diego, in La Jolla have used the technique to determine the amount of Cdc20 in living...
Gold beads help image eye movements
Jun 1, 2006 — Imaging methods such as MRI cannot capture movements of much of the eye’s orbit — the cone-shaped bony cavity that protects the eye. Because the movements of the eye’s muscles and connective tissue are unknown, scientists do not...
Gold stars offer new rewards
Jun 1, 2006 — The size- and shape-dependent emission of noble metal nanoparticles makes them useful for applications such as sensing and labeling and even for nanoscale optical waveguides. For sensing, these particles can detect molecular binding because their...
Microscope Takes Deep-UV and Visible Picosecond Fluorescence Lifetime Measurements
Jun 1, 2006 — Time-resolved microscopy is the ultimate tool for investigating dynamic events in cells and subcellular structures. However, it previously was limited when used for applications that required wavelengths longer than 370 nm because of microscope...
On the Path Toward More Useful Fluorophores
Jun 1, 2006 — Where would modern biomedical research be today without fluorescent probes? Some would argue that it would be blindly groping down a dark alley, with no efficient means of discovering the finely honed interplay of proteins and other substances in...
One laser does the work of three
Jun 1, 2006 — When it comes to laser sources, three are definitely a crowd. That is particularly true when trying to align multiple beams to illuminate the same confocal volume. So researchers at the National University of Singapore used just one beam and...
Adjustable lenses may mean no more bifocals
May 1, 2006 — Along with thinning hair, a few more wrinkles and some added pounds, by age 50 nearly everyone notices that print seems harder to read. It’s the result of presbyopia, an age-related inability of the eye to focus on near objects. Solutions...
Building protein microstructures with less expensive lasers
May 1, 2006 — The emission from a femtosecond Ti:sapphire laser can be used to create miniature structures made of protein that fence in a living bacterium. Fabricating structures in this way could someday be used to engineer neuronal networks for prosthetics or...
Camera Phones Emerge as a Health Care Tool
May 1, 2006 — Telemedicine gives patients access to a doctor no matter where they are. Whether a patient uses monitoring equipment to send information to the doctor’s office or an x-ray technician transmits images to a radiologist for examination,...
Creating Clarity: Adaptive Optics for Bioimaging
May 1, 2006 — Biological imaging instruments often have resolution limitations that restrict the ability of researchers and clinicians to detect critical detail. One reason is that, as light passes through tissue to reach the object of interest — a cell,...
Diamond biosensors are forever
May 1, 2006 — To make effective biosensors, the detection molecules must be attached to a microelectronics-compatible surface in such a way that it is highly stable for long periods. Combinations of biomolecules and commonly used substrate materials such as...
Engineering and Physical Sciences Research Council
May 1, 2006 — The Engineering and Physical Sciences Research Council of Swindon, UK, and Philips Research of Best, the Netherlands, have formed an alliance to fund research and training in biomedical diagnostic technologies. The four-year joint research framework...
Fluid sensors
May 1, 2006 — A literature package titled “Fluid Sensors for Medical OEMs” from Gems Sensors & Controls Inc. describes the company’s compact liquid level switches, flow and pressure sensors, and electro-optic single-point level sensors for...
Invitrogen Corp.
May 1, 2006 — Invitrogen Corp. of Carlsbad, Calif., has entered into an agreement with the National Institutes of Health Chemical Genomics Center in Bethesda, Md., to identify small molecules that modulate key signaling pathways associated with disease...
Miniature 2-D flow cytometer
May 1, 2006 — Conventional flow cytometers are large and expensive and usually provide one-dimensional data, but two-dimensional data is needed for detecting subtle differences in the morphology of cells. Researchers from the University of Alberta in Edmonton,...
Miniature lenses for tiny microarray spots
May 1, 2006 — Although microarrays may seem small, they’re too big, at least for portability. Miniaturizing them further is difficult because they consist of many sensing spots. The individual spots are small, but most arrays manufactured today are...
Modified GFP enables in vivo imaging of cellular signaling in the heart
May 1, 2006 — The efficient functioning of the heart — an organ that begins to operate before it is fully developed — depends on the coordinated release and reuptake of calcium ions from organelles within cells. Subtle dysfunctions of this process can...
Multicolor analysis extends potential of DNA microarrays
May 1, 2006 — Microarray platforms are used everywhere — from academic research centers to public health laboratories to pharmaceutical companies. By enabling analysis of thousands of DNA sequences at a time, they have dramatically increased throughput and...
Multislice CT may effectively image diseased arteries
May 1, 2006 — Invasive coronary angiography remains the only acceptable technique for imaging coronary artery stenoses in the clinic, despite such disadvantages as its cost, the inconvenience to patients and its nonnegligible, if small, risk of complications....
Scientists successfully mimic insect eyes
May 1, 2006 — Imagine being able to see more than a 90° field of view without turning your head. Because of their compound eyes, insects can, but so far, only fish-eye lenses can artificially accomplish this, and they are bulky and require multiple lenses and...
Self-illuminating quantum dots aid in vivo imaging
May 1, 2006 — Quantum dots are useful for biological imaging because they are stable and bright, and their emission depends on their size. Researchers can pick quantum dots of a certain emission to match their application or use several sizes for multiplexing....
Tracking eyes reveals surprises about autism
May 1, 2006 — In studying autism, researchers have struggled with a basic problem: interviewing subjects. Because the condition is characterized by difficulty in social interactions, investigators have turned to eye tracking. However, eye-tracking headgear is so...
Whirling-fiber endoscope allows two-photon imaging
May 1, 2006 — Two-photon imaging could be a useful medical technique if a suitable in vivo probe were available. Such a probe must be capable of rapidly scanning across a reasonably large area, and it must effectively deliver the excitation radiation and,...
A Spotlight on Biophotonics in Canada
Apr 1, 2006 — Canada has demonstrated its commitment to building a sustainable future for biophotonics through education, research and industrial development. Numerous initiatives exist, at federal and provincial levels, whose mandate is to establish a firm...
Biosensing with microlenses
Apr 1, 2006 — To see something small, you need a magnifier — and that is what a group of researchers at the Georgia Institute of Technology in Atlanta turned to in developing a label-free biosensor. For their work, they used hydrogel microlenses to monitor...
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May/Jun 2024
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