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BioPhotonics is the global resource for research, business and product news and information for the biophotonics community and the industry's only stand-alone print and digital magazine. Stay current with a FREE subscription, and expand your knowledge of light and the life sciences through our extensive, industry-specific archives.

Latest Issue
Mar 2018

Biomedical Impacts of LEDs

Marcia StamellOur cover story this month talks about advances to endoscopy brought about by the emergence of LEDs as the procedure’s preferred light source. LED systems reduce eyestrain and optimize contrast of the tissue morphology because they allow users to adjust the makeup of the light. But as Kavita Aswani, Tara Maggiano and James Clements of Excelitas explain, modern LED light sources also enable surgeons to both view the visible area of interest and gather additional information through the excitation of biomarkers. This change, they say, opens the way for better diagnosis, greater surgical precision and faster recovery times. “LED Technology Advances Endoscopy” (read article).

LED light is also a feature in a microscopy platform that enables high-speed imaging of tissue samples, which is the subject of an article by Cody Daniel of 3Scan. The system integrates a high-speed camera with an automated microtome coupled to an LED light source that transmits light through the bevel of the blade. It can generate as many as 50,000 section images in a few hours and be rendered into 3D. This capacity promises to yield more accurate diagnosis of tissue than is available through limited sampling and can open the way to answering complex research questions. “Histology Breaks a Speed Barrier” (read article).

Elsewhere in the magazine:

• Sophie Brasselet of Institut Fresnel writes about the use of a variant of coherent Raman scattering (CRS) to diagnose lipid loss at an early stage in neurological disorders. Polarized-resolved CRS can increase sensitivity to molecular organization to reveal deformation of the myelin membrane at the ~100 nm scale. It shows promise for the diagnosis and treatment of conditions such as Alzheimer’s, Parkinson’s and multiple sclerosis. “Polarization-Resolved CRS Reveals Lipid Disorder at the Molecular Scale” (read article).

• Science Writer Valerie Coffey reports on photonics that gleans ideas from the way organisms interact with light. These interactions are then translated into photonics technology and manmade systems. The potential uses of these bio-inspired photonics are varied — from tunable filters and microlenses to bio-optical sensors. “Bio-Inspired Photonics Comes Full Circle,” (read article).

• For our Biopinion, Laura Marcu of the University of California, Davis, calls for accelerating the adoption of fluorescence lifetime imaging (FLIM) into clinical practice. The technique shows great promise for intraoperative real-time diagnostics during tumor removal, improving both surgical outcomes and patient quality of life. But adoption is hampered by the limited ability to validate endogenous fluorescence signals against gold standard techniques. “FLIM delineates tumor margins in real time” (read article).

• And in our special section, Matthias Schulze of Coherent Inc. writes about trends in biomedical lasers for therapeutics (read article).

Enjoy the issue.
Mike Wheeler
An award-winning journalist with more than 20 years of experience, Managing Editor Michael D. Wheeler oversees editorial content for Photonics Spectra, EuroPhotonics, BioPhotonics and Industrial Photonics magazines.
Marcia Stamell
Associate Managing Editor Marcia Stamell is the editor of BioPhotonics and Industrial Photonics. She has worked for general interest newspapers, the business press and national magazines as a writer and editor.
Justine Murphy
Senior Editor Justine Murphy is an award-winning journalist with nearly 20 years of experience. She serves as editor of EuroPhotonics, host of Light Matters and producer of podcasts. She also leads development of magazine special sections and marketing projects.
Autum Pylant
News Editor Autum C. Pylant is an Air Force Veteran with 10+ years of award-winning broadcast journalism experience. She is responsible for the steady flow of news and new product announcements to web and print and is the producer of the Light Matters video newscast.
Robin Riley
Multimedia/Web Editor Robin Riley has 30+ years of experience in communications and marketing for a range of technical industries. She is a regular contributor to web content and social media, and organizes and produces custom and editorial webinars.
Karen Newman
Karen Newman, Publisher/Books & Courses for Photonics Media Press, has had a career in business-to-business and association publishing, much of it spent covering technical, scientific and life sciences subjects.
Hank Hogan
Contributing editor Hank Hogan holds a Bachelor of Science degree in physics from the University of Texas at Austin. Hogan worked in the semiconductor industry and now writes about science and technology.
Marie Freebody
Contributing editor Marie Freebody is a free-lance science and technology journalist with a master’s degree in physics and a concentration in nuclear astrophysics from the University of Surrey in England.
Valerie Coffey
Science writer Valerie C. Coffey holds a bachelor’s degree in physics and a master’s in astronomy. She has covered optics, photonics, physics and astronomy for a variety of industry and academic publications since 2000.
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