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Machine Learning Enables Label-Free Prediction of 3D Images from Transmitted-Light Microscopy SEATTLE, Sept. 21, 2018 — Scientists at the Allen Institute have used machine learning to develop a label-free tool for predicting 3D fluorescence directly from transmitted-light images. Instead of fluorescence microscopy, the new method uses only black-and-white images generated by a bright-field microscope. To the human eye, cells viewed in a bright-field microscope are sacs rendered in shades of gray. A trained scientist can find the edges of a cell and the nucleus, but not much else. Using a convolutional
Baycrest Brain Imaging Project Joins International Partners TORONTO, Sept. 19, 2018 — The Virtual Brain (TVB), an open-source modelling platform that captures intricate details of the brain's structure and function through the collection of imaging data, has joined a European research enterprise to advance neuroscience, medicine, and...
Access Optics Gains ISO Certification BROKEN ARROW, Okla., Sept. 18, 2018 — OEM medical device and defense optics supplier Access Optics LLC has announced ISO 13485:2016 certification for its medical device and quality management systems. The certification is a requirement for regulatory purposes and is an international...
Microscopy Add-On Enhances Neuronal Image Resolution Under Dim Conditions TEL AVIV, Israel, Sept. 18, 2018 — A new add-on for laser-scanning microscopes, built from commercially available hardware and open-source software, could improve the quality of 2D and 3D imaging of neuronal activity in the living brain, even under photon-deprived imaging conditions....
Intel and Philips Accelerate Deep Learning Inference on CPUs in Key Medical Imaging Uses SANTA CLARA, Calif., Sept. 14, 2018 — Intel and Philips have tested two health care use cases for deep learning inference models. In these tests, Intel and Philips achieved a speed improvement of 188× for a bone-age-prediction model, and a 38× speed improvement for a...
Optical Trapping and Raman Spectroscopy Are Combined to Measure Live Cell Interaction NOTTINGHAM, England, and GLASGOW, Scotland, Sept. 13, 2018 — Using multiple laser beams and Raman spectroscopy, researchers at the Universities of Nottingham and Glasgow have designed and built a new instrument that could help scientists learn more about how infections take hold and how antibiotic-resistant...
Tunable Color-Generating Mechanism in Nature Could Inspire Biophotonic Applications SINGAPORE and FRIBOURG, Switzerland, Sept. 12, 2018 — Researchers from Yale-NUS College and the University of Fribourg have discovered a color-generation mechanism in nature, which, if harnessed, could potentially be used to create screen displays that project the same image when viewed from any angle,...
Oxide Acquires VUV Laser Business from Lumeras YAMANASHI, Japan, Sept. 5, 2018 — Oxide Corp. has acquired the vacuum ultraviolet (VUV) laser business from Lumeras LLC. Lumeras produces high-photon-energy (11 eV, λ = 114 nm) laser sources used in research institutes worldwide for cutting-edge materials science...
3D-Printed Photodetectors on Curved Surface Could be Basis for 'Bionic Eye' MINNEAPOLIS, Minn., Aug. 30, 2018 — A University of Minnesota research team has 3D-printed an array of light receptors on a hemispherical surface, in a first step toward creating a “bionic eye” that could someday help blind people see or sighted people see better. Using...
5D HSI Measures Shape and Spectral Characteristics as a Function of Time JENA, Germany, Aug. 29, 2018 — A 5D hyperspectral imaging system (HSI) — so-called because it captures multiple wavelengths of light plus spatial coordinates as a function of time — has been developed by a team at Friedrich Schiller University Jena and the Fraunhofer...
Pitt’s Kozai Awarded Grant to Improve Design of Brain Implants PITTSBURGH, Aug. 29, 2018 — Takashi Kozai, assistant professor of bioengineering at the University of Pittsburgh (Pitt) Swanson School of Engineering, has been awarded an R21 grant from the National Institutes of Health (NIH) to improve the design of chronic brain implants by...
Hand-Held Imager Could Broaden Use of AOSLO DURHAM, N.C., Aug. 27, 2018 — Researchers at Duke University have miniaturized adaptive optics (AO) technology to develop a portable hand-held ophthalmology device that can image individual photoreceptors in the eye at high resolution. The new instrument could allow improved...
BioTek Granted US Patent for Autofocus in Microplate Reader, Imaging Software WINOOSKI, Vt., Aug. 24, 2018 — Life science instrumentation developer BioTek Instruments Inc. was issued a patent by the U.S. Patent and Trademark Office for its User-Trained Autofocus feature in its Gen5 Microplate Reader and Imager Software integrated with advanced cell imaging...
Biosensor Monitors Oxygen in Organ-on-a-Chip Systems RALEIGH, N.C., Aug. 21, 2018 — A new photonic biosensor can track oxygen levels in real time in organs-on-a-chip to ensure that these systems are mimicking the function of physical organs. Developed at North Carolina State University and the University of North Carolina, Chapel...
Science Exchange to Offer LI-COR Imaging Suite LINCOLN, Neb., Aug. 20, 2018 — Imaging systems developer LI-COR Biosciences is collaborating with Science Exchange, an outsourced R&D marketplace, to offer a suite of molecular imaging services based on LI-COR’s pioneer work in NIR fluorescence as a detection method....
Nanoplasmonics Enables Label-Free Measurement of Bacteria Formation OKINAWA, Japan, Aug. 16, 2018 — Using nanochip technology and a targeted beam of light, scientists have devised a real-time, label-free way to monitor biofilms, an important component in the search for alternatives to bacteria-resistant antibiotics. The team from the Okinawa...
Device Built via Laser Lift-Off Could Advance Precision Medicine DAEJEON, South Korea, Aug. 15, 2018 — Researchers have fabricated a flexible drug delivery microdevice (f-DDM) with controlled release using a laser micromachining technique. The device could provide controlled release for personalized drug therapy to organs with curved surfaces, such...
Gooch & Housego Acquires Integrated Technologies ILMINSTER, England, Aug. 13, 2018 — Gooch & Housego (G&H) has completed the acquisition of Integrated Technologies Ltd. (ITL). ITL provides full product development, design, manufacturing, and after-sales service for the commercialization of medical diagnostic, analytical,...
Low-Level Light Therapy Treats Digital Ulcers MANCHESTER, England, Aug. 9, 2018 — A lamp containing 32 bulbs emitting IR, red, or UV light for use in low-level light therapy (LLLT) was tested on finger ulcers caused by an autoimmune condition. Researcher Michael Hughes, from the University of Manchester, said that the promising...
Photoacoustic Ultrasound Can Be Used to Measure Periodontal Health LA JOLLA, Calif., Aug. 9, 2018 — Researchers from University of California, San Diego used photoacoustic (optoacoustic) imaging with a contrast agent to measure pocket depths in swine models. The measurements were compared to those taken with a periodontal probe. Results showed...
Blue Light Excites Retinal, Intercepts Cellular Signaling in the Eye TOLEDO, Ohio, Aug. 9, 2018 — An optical chemistry research study has shown how blue light from digital devices and the sun can cause the death of retinal molecules, increasing potential for age-related macular degeneration. Photoreceptor chromophore 11-cis retinal (11CR) and...
3D Printing Provides Way to Fabricate Probes Used in Cancer Research ABU DHABI, Aug. 8, 2018 — Researchers at NYU Abu Dhabi have used a 3D printer to create a functional, integrated and inexpensive microfluidic probe (MFP). Typically made of glass or silicon, MFPs are tiny scientific tools used to study, process, and manipulate live cell...
Cardiovascular Systems, Aerolase Sign Agreement for Laser Atherectomy Technology ST. PAUL, Minn., Aug. 7, 2018 — Cardiovascular Systems Inc. (CSI), a medical device company that develops and commercializes interventional treatment systems for patients with peripheral and coronary artery disease, has signed an agreement with Aerolase Corp. to co-develop a new...
Avinger Begins Study on OCT, IVUS for Treating Peripheral Artery Disease REDWOOD CITY, Calif., Aug. 6, 2018 — Medical device developer Avinger Inc. has begun a study comparing optical coherence tomography (OCT) with intravascular ultrasound (IVUS) as imaging tools for diagnosing and treating peripheral artery disease (PAD). Avinger designs and develops...
Fluorescent Probe Identifies Cancer Stem Cells in the Body CHAMPAIGN, Ill., Aug. 3, 2018 — A fluorescent probe, called AlDeSense, has demonstrated the ability to find and track cancer stem cells (CSCs) in cultures of multiple human cancer cell lines as well as in live mice. The new probe is a small molecule that binds to an enzyme...
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