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Fiber Solutions in 0.3 to 16µm Range Enable Specialized Biomedical Applications
Fiber solutions for biomedical applications in the 0.3-16µm range include those utilized for multispectral diagnostics to define tumor margins and to detect osteoarthritis. IR-endoscopes and...
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SERS-Based Biophotonics: From Nanotags to Point-of-Care Testing
Today, surface-enhanced Raman scattering (SERS) is widely used in the chemical, life, and material sciences. This presentation begins with a short tutorial on the fundamentals of SERS. ...
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Comparison of Broadband Spectroscopy Techniques for Rapid Detection of Urea in Peritoneal Dialysis Fluid
Each year about 2 million patients worldwide are affected by kidney failure and find themselves in need of dialysis. While traditional hemodialysis is still used in most cases, peritoneal dialysis...
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Multiplexed Sensing Devices: The Use of Nanomaterials for Improving Optics-Based Smart Diagnostic Devices
The onset of the COVID-19 pandemic has generated a new area of research that is focused on creating highly effective biosensors. As such, the development of photonic based multiplexed devices for...
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Meta-LASE Microscopy for Visualizing Virtual Histology and Tissue Energetics
A novel new form of ultraviolet microscopy has been developed, called metabolic light absorption, scattering, and emission (Meta-LASE) microscopy, which enables the simultaneous imaging of optical...
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Label-Free Multicellular Imaging by Engineering the Light
New generations of laser sources, with high pulse energy, wide continuous tunable range, and a compact form, are in high demand to advance two-photon and three-photon microscopy to its full potential...
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Expansion-Assisted Selective Plane Illumination Microscopy Captures Large and Small Biological Detail
Recent advances in tissue processing, labeling, and fluorescence microscopy are providing unprecedented views of the structure of cells and tissues at sub-diffraction resolutions and near single...
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Ultrashort Sub-50-fs Pulses Enable New Dimensions in Multiphoton Microscopy
Multiphoton excitation and nonlinear imaging microscopy are being used increasingly in biomedical research for high-resolution live-cell imaging. However, traditional single photon techniques have a...
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Microscope Objective Design for Life Science Investigation
Microscope objectives are critical for a vast range of biological imaging applications ranging from multiphoton microscopy to differential interference contrast microscopy. The high level of accuracy...
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Vibrational Photothermal Microscopy Provides a Picture of Life in Live Cells
Recently developed mid-infrared photothermal (MIP) microscopy opens a new window to look at molecules inside a living cell. In MIP microscopy, a visible beam is used to probe the local change of...
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Multimodal Multiphoton Imaging in Life Sciences Exploration
High-quality imaging of samples in 3D and 4D, as well as label-free and non-destructive imaging of unique biomarkers, is becoming more important in understanding cellular mechanisms and their...
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Adaptive Optics in Microscopy: Practical Use of Wavefront Correctors and Control Methods
Adaptive optics can be used to correct for instrument and sample aberrations or to dynamically shape the wavefront and point spread function (PSF) to create new possibilities or reduce instrument...
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Achieving Optical Sectioning for Whole Slide Imaging
Whole slide imaging (WSI) is increasingly important for research as it achieves the acquisition of large scan areas at high resolution within seconds. Based on widefield microscopy, the fluorescent...
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Speeding Up Microscopy and Image Analytics: Integrating Techniques
Pairing up the capabilities of optical microscopy and computer vision is a common strategy to enhance the performance of a broad spectrum of biological and biomedical screening applications. The most...
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Let's Talk Laser Stability in Microscopy
It is no longer sufficient for a laser to work fine for several days in a nonlinear microscopy lab. Routine two- and three-photon imaging depends on reliable laser output parameters over weeks and...
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Join Photonics Media online Oct. 24-26 for the BioPhotonics Conference, a virtual event highlighting innovation in the life sciences and biomedical optics. The conference will feature three keynotes...
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Advancing and Extending the Spectral Range for Imaging in Fluorescence Microscopy
Fluorescence microscopy has revolutionized life sciences by enabling researchers to study biological samples with exceptional precision. New excitation and illumination light sources and scientific...
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New Frontiers in Terahertz Technology
Although unique potentials of terahertz waves for chemical identification, material characterization, biological sensing, and medical imaging have been recognized for quite a while, the relatively...
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Nanoscale Imaging Techniques
Golshan Coleiny of Fundamental Optical Solutions shares a brief history of nanoscale imaging with a focus on optical technologies, addressing many of today’s challenges in optical limitation...
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Confronting the Drug Epidemic with Portable Spectroscopy
According to the United Nation’s 2022 World Drug Report, there was a 26% increase in drug use by 15- to 64-year-olds in the last decade, with approximately 284 million illicit drug users in...
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New Advances in the Use of Molecular Emission Created by LIBS for Fluoride Imaging in Medicine
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and laser-induced breakdown spectroscopy (LIBS) are becoming increasingly important tools for analysis and imaging in medicine....
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Implementation of Raman Spectroscopy for Analyzing Food
Raman spectroscopy is a powerful analytical technique that enables the quick and non-destructive identification of chemical signatures of a sample analyte. With the added capability of integrating...
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Non-Invasive Glucose Monitoring Techniques using QCL-IR Lasers
There are 422 million people worldwide living with diabetes1, and current methods for monitoring blood glucose levels are painful, invasive, and can potentially require surgical procedures....
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PCR-Based Analysis of a Common Fluorescein Derivative Using Broadband Spectroscopy Platforms
PCR-based testing has rapidly increased in popularity and development since the start of the COVID-19 pandemic, and many new techniques are leveraging the latest performance advancements offered by...
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Fact or Fiction: Multidimensional Fluorescence Serves as a Reproducible Analytical Tool
Multidimensional fluorescence is a powerful spectroscopic approach to the analysis of complex mixtures. It tackles routine analytical problems that require sensitivity and selectivity that FT-IR,...
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April 2024
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