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FLIM News
Technique Enhances Effect of Fluorescence Lifetime Microscopy
TOKUSHIMA, Japan, Jan. 7, 2021 — Researchers from Tokushima University have developed a method of fluorescence lifetime microscopy that does not require mechanical scanning. The technique drastically increases the effectiveness of fluorescence lifetime microscopy (FLIM). A major...
In Vivo Imaging with FLIM Shows Effect of Experience on Neuronal Activity
JUPITER, Fla., Dec. 30, 2019 — Every day, the neuronal connections within our brains change depending on what we learn and experience in our daily lives. Specialized proteins, called activity-dependent transcription factors, activate genes within the cells of the brain to help it...
Catheter Combines Ultrasound and Multispectral Fluorescence to Measure Arterial Plaque
DAVIS, Calif., Oct. 6, 2017 — A novel cardiac catheter probe combines intravascular ultrasound (IVUS) and fluorescence lifetime imaging (FLIm) in a single device that can image the arteries of a living heart. The catheter can simultaneously retrieve structural and biochemical...
Ultrafast Lasers Enable High-Density Data Storage
OTTAWA, Ontario, June 22, 2016 — A laser-based data storage and retrieval technique could increase the storage capacity of conventional optical discs, such as DVD and Blu-ray, without the need for special preparatory steps. The scalable technique stores information bits in a...
Microscopy Brings New Worlds Into Focus
May 31, 2016 — Though the father-son duo of Hans and Zacharias Janssen is widely credited with developing the first microscope in the late 16th century, it was the English scholar Robert Hooke who inspired widespread public interest in the new science of...
FLIM OPT Monitors Cell Signaling in Live Organisms
LONDON, May 17, 2016 — Fluorescence Lifetime Imaging (FLIM) combined with Optical Projection Tomography (OPT) has been used to image and monitor apoptosis in whole live organisms in 3D. Termed FLIM OPT, the method may provide a means to visualize cell signaling processes...
Spectroscopy Optimizes Fluorescent Probes for DNA Study
HOUSTON, Sept. 7, 2012 — Time-resolved spectroscopy plus careful calculations can optimize photoluminescent probes for studying DNA, with results nearly twice as good as standard fluorescence spectroscopy for specific sequences, according to a new paper from Rice...
Molecules 'Light Up' Alzheimer's Roots
HOUSTON, July 14, 2011 — A breakthrough in sensing at Rice University could make finding signs of Alzheimer's disease nearly as simple as switching on a light, and should help bring about better medications to treat the devastating disease. The lab of bioengineer...
Multimodal Imaging: Combining Techniques to Give Microscopists a Boost
May 24, 2011 — On the way to conjoining two well-established but disparate imaging modalities, a FLIM (fluorescence lifetime imaging) and CARS microscope was achieved along with the development of an adapter that could bring real change to the way microscopists...
McMaster Lab Protein Study Targets Huntington's
HAMILTON, Ontario, Feb. 28, 2007 -- A new bioimaging facility at McMaster University is shedding light on how kinase inhibitors might prevent the protein that causes Huntington's disease from accumulating in the nucleus of brain cells, which could ultimately lead to a treatment for...
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April 2024
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