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MICROSCOPY HANDBOOK ARTICLES
Superresolution Microscopy: An Imaging Revolution Jan 18, 2017 — Superresolution optical microscopy has been one of the most momentous developments in the life sciences over the last decade — and its evolution is ongoing. Progress has been so rapid and significant that it has been dubbed by some observers as “the resolution revolution.” The demands from biomedical applications are very wide — ranging from the need for high spatial and temporal resolution, long acquisition time, 3D imaging, deep tissue/in vivo imaging and so on.
Measuring Surface Roughness: The Benefits of Laser Confocal Microscopy Feb 10, 2016 — When evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and rough,” “like oxidized silver,” or “like a mirror.” The differences indicated...
Nanopositioning: A Step Ahead Feb 1, 2016 — It is almost a cliché among students of creativity that innovation occurs at the intersection of fields. Since nanopositioning is a discipline that has enabled swiftly evolving application arenas as diverse as materials science, genomics, photonics,...
Microscopy Illumination: Considering Nonlaser Light Sources Jan 19, 2016 — As recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an arc source, typically 100 W mercury. Today, there...
Lasers for Microscopy: Major Trends Feb 4, 2015 — Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics, and other areas of neuroscience, and even a shift in...
Interferometry: Measuring with Light Jan 1, 2015 — Long applied to optical shop testing, interferometry is now used to measure many different types of parts in a variety of applications, such as optical system performance, surface roughness, surface form, and displacement of moving surfaces. An...
NSOM: Discovering New Worlds Apr 13, 2006 — Near-field scanning optical microscopy (NSOM) is an optical microscopy technique capable of imaging objects with a resolution below the diffraction limit of conventional (far-field) microscopy; i.e., below approximately half the wavelength of the...
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