In the field of optical imaging, the ability to image tumors at depth with high selectivity and specificity remains challenging. Although surface enhanced resonant Raman scattering (SERRS)...

The characterization and control of optical systems with multiple stand-alone pieces of test equipment often presents difficult challenges that lead to lower stability, more noise, and increased...

When it comes to analyzing periodic signals, selecting the appropriate measurement tool is crucial for achieving accurate and meaningful results. Gustavo Ciardi of Zurich Instruments delves into the...

A novel new form of ultraviolet microscopy has been developed, called metabolic light absorption, scattering, and emission (Meta-LASE) microscopy, which enables the simultaneous imaging of optical...

New generations of laser sources, with high pulse energy, wide continuous tunable range, and a compact form, are in high demand to advance two-photon and three-photon microscopy to its full potential...

Recent advances in tissue processing, labeling, and fluorescence microscopy are providing unprecedented views of the structure of cells and tissues at sub-diffraction resolutions and near single...

Multiphoton excitation and nonlinear imaging microscopy are being used increasingly in biomedical research for high-resolution live-cell imaging. However, traditional single photon techniques have a...

Microscope objectives are critical for a vast range of biological imaging applications ranging from multiphoton microscopy to differential interference contrast microscopy. The high level of accuracy...

Recently developed mid-infrared photothermal (MIP) microscopy opens a new window to look at molecules inside a living cell. In MIP microscopy, a visible beam is used to probe the local change of...

High-quality imaging of samples in 3D and 4D, as well as label-free and non-destructive imaging of unique biomarkers, is becoming more important in understanding cellular mechanisms and their...

Adaptive optics can be used to correct for instrument and sample aberrations or to dynamically shape the wavefront and point spread function (PSF) to create new possibilities or reduce instrument...

Whole slide imaging (WSI) is increasingly important for research as it achieves the acquisition of large scan areas at high resolution within seconds. Based on widefield microscopy, the fluorescent...

Pairing up the capabilities of optical microscopy and computer vision is a common strategy to enhance the performance of a broad spectrum of biological and biomedical screening applications. The most...

It is no longer sufficient for a laser to work fine for several days in a nonlinear microscopy lab. Routine two- and three-photon imaging depends on reliable laser output parameters over weeks and...

Join Photonics Media online Oct. 24-26 for the BioPhotonics Conference, a virtual event highlighting innovation in the life sciences and biomedical optics. The conference will feature three keynotes...

Golshan Coleiny of Fundamental Optical Solutions shares a brief history of nanoscale imaging with a focus on optical technologies, addressing many of today’s challenges in optical limitation...

Microscope objectives are critical for high magnification machine vision applications such as semiconductor inspection. There are different key considerations when choosing the right objective...

Liquid Instruments co-founder and CEO Daniel Shaddock shares next-generation strategies to perform optical phase locking using digitally implemented, FPGA-based lock-in amplifiers and phasemeters. He...

Optical photothermal infrared (O-PTIR) spectroscopy has established itself as a cutting edge vibrational microspectroscopy tool. It offers significant advantages over traditional FTIR,...

Raman imaging microscopy is a highly versatile and effective tool for the label-free, nondestructive chemical characterization of materials. Based on the Raman effect, which describes a distinct...

Stimulated Raman scattering (SRS) microscopy has become a powerful chemical imaging tool that shows significant promise in numerous biological and biomedical applications. In a typical SRS microscopy...

The size and number of images for image acquisition instruments and processing techniques have grown exponentially, along with the associated storage needs and network requirements. In the fields...

Photoacoustic imaging is a novel hybrid imaging technique that combines both optical and ultrasound imaging. In this technique, a short-pulsed laser source illuminates the tissue to generate sound...

Chemical microscopy that utilizes fingerprint vibrational spectroscopic signals opens a new window to visualizing the orchestra of molecules and biological structures inside living systems. Ji-Xin...

Raman imaging is a versatile, label-free, and nondestructive microscopy technique that can characterize many types of materials, including biological samples. It provides information about their...