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fluorophores News
Fluorescent Protein Combines Record Brightness with Fast Folding
AMSTERDAM, April 13, 2023 — The University of Amsterdam research team that introduced the red fluorescent protein known as mScarlet in 2016 has introduced an improved variant of the marker. A version of mScarlet called mScarlet3 delivers a quantum yield of 75% and a fluorescence lifetime of 4.0 ns. In addition to providing what the researchers said is record-level brightness, mScarlet3 provides fast, complete maturation. Fluorescent proteins like mScarlet3 are attached to cells to help scientists observe the
Human Limb Model Could Evaluate Fluorophores for Safety in Surgery
BELLINGHAM, Wash., Jan. 25, 2023 — As the popularity of fluorescence-guided surgery grows, so does the demand to design and develop fluorophores, which serves to distinguish the target tissue from other tissues and subsequently guide surgical steps. The current list of FDA-approved...
Fluorophore Modified to Expand Monitoring of Cell Dynamics
OSAKA, Japan, Nov. 28, 2022 — A genetically modified fluorescent protein has exhibited the shortest fluorescence emission wavelength to date, researchers at Osaka University reported. The fluorophore, named Sumire, emits 414-nm violet fluorescence from a hydrated chromophore....
Imaging System Speeds Diagnosis with Real-Time Biopsy Analysis
ROCHESTER, N.Y., Oct. 13, 2022 — Results of a pilot study conducted at the University of Rochester showed that a system based on two-photon fluorescence microscopy (TPFM) enabled rapid diagnosis of nonmelanoma skin cancer through real-time imaging of unprocessed, fresh tissue...
Internal Reflection-Based Microscopy Images Single Protein
PHOENIX, May 5, 2022 — A team from Arizona State University (ASU) has introduced evanescent scattering microscopy (ESM), a label-free method for sensitive imaging of biomolecules, including proteins. The single-molecule microscopy technique is based on total internal...
Cytek Extends its Flow Cytometry Capabilities
FREMONT, Calif., Nov. 3, 2021 — Cell analysis solutions company Cytek Biosciences has acquired the cell analysis business of Tonbo Biosciences. The deal includes the acquired business’s portfolio of research reagents, which supports additional applications — cell...
Optical Method Enables Drug Toxicological Assessments in Early-Stage Tests
GENOA, ITALY, Oct. 11, 2021 — An Italian Institute of Technology (IIT)-coordinated project has received €3 million ($3.47 million) from the European Union to develop a biosensor based on a novel virtual mirror design. Researchers said the biosensor will be able to detect...
Scientists Confirm Dynamin Molecular Motor’s Constriction Mechanism
KANZAWA, Japan, Sept. 3, 2021 — A team at Kanzawa University used the measurement technique of single-molecule fluorescence resonance energy transfer, or smFRET, as well as a computable model, to develop a method that determined the strength of an individual dynamin motor....
New Technique Visualizes Live Cells
NEW YORK, March 3, 2014 — A new optical imaging platform represents a significant step toward a longstanding scientific goal: visualizing small biomolecules inside living biological systems with minimum disturbance.
Fluorescent fingerprint tag IDs ‘hidden’ prints
LEICESTER, England – Criminals might want to think twice before touching anything, now that a new fluorescent tagging technique could yield more usable results from latent fingerprints on metal surfaces. The odds that any two people have identical fingerprints are...
Fluorescent fingerprint tag IDs ‘hidden’ prints
LEICESTER, England – Criminals might want to think twice before touching anything, now that a new fluorescent tagging technique could yield more usable results from latent fingerprints on metal surfaces. The odds that any two people have identical fingerprints are 64...
Fluorescent Fingerprint Tag IDs ‘Hidden’ Prints
LEICESTER, England, July 3, 2013 — Criminals might want to think twice before touching anything, now that a new fluorescent tagging technique could yield higher-confidence identifications from latent fingerprints on metal surfaces.
2011 Prism Award Winners Announced
SAN FRANCISCO, Jan. 26, 2012 — Amplitude Systèmes, PD-LD and 89 North were among nine winners of Prism Awards for photonics innovation announced by Photonics Media and SPIE at a gala banquet Wednesday night during Photonics West. The fourth annual Prism Awards honored 28...
Gold nanoantenna enhances plasmonic sensing
BERKELEY, Calif. – The first reported experimental demonstration of antenna-enhanced gas sensing at the single-particle level holds great promise for plasmonic sensing. By placing a palladium nanoparticle on the focusing tip of a gold nanoantenna, researchers with...
Artificial White Light is Eye-friendly
WARSAW, Oct. 8, 2010 — A newly discovered class of organic substances that emit white light with a continuous spectrum is providing experimental evidence that only single component luminophore will be necessary to construct eye-friendly light sources and displays. ...
The Quantum Leap: Researchers Explore the Clinical Potential of Quantum Dots
Aug 23, 2010 — Researchers have made tremendous progress in recent years in developing optical imaging for the study and management of disease. By taking advantage of the near-infrared window — the wavelength range where scattering and absorption of light...
Photothermal imaging detects nanorod orientation
HOUSTON – “Fluorescence vector probes and polarization-sensitive single-molecule spectroscopies have been widely used to explore the conformation dynamics of proteins in biological systems – and an ideal probe should yield high signal with low...
White light supercontinuum: Power struggle
LILLE, France – Researchers are pioneering a practical way of generating high-power white light suitable for applications including spectroscopy, microscopy and optical coherence tomography. Produ...
Tracking Particles With Gold Rods
HOUSTON, Feb. 8, 2010 – A group of Rice University researchers, led by Stephan Link, has found a way to use nanometer-scale gold rods as orientation sensors by combining their plasmonic properties with polarization-imaging techniques. The work may make it possible to see...
FLUOROPHORES POSTER
May 1, 2009 — Omega Optical Inc. has released an updated version of its “The Essence of Fluorescence” poster, which won the Science and Engineering Visualization Challenge award in 2005. The resource has been updated with about 130 fluorophores, their excitation...
FILTERS
Apr 1, 2009 — Omega Optical has released its Filters for Fluorescence and Life Science Instrumentation Catalog 2009. The publication enables customers to find products through approaches such as product family, center wavelength, cut-on, fluorophore and...
Omega Optical Unveils Poster, Catalog
Feb 5, 2009 — Omega Optical Inc., maker of optical filters and coatings, has revised its award-winning poster, “The Essence of Fluorescence,” which won the Science and Engineering Visualization Challenge in 2005. Measuring 38 × 16 in., it previously listed more...
Nanobeads Prove Useful for Making Optical Molecular Sensors
Mar 1, 2008 — Optical chemical sensors are employed for testing in numerous fields, from marine research to the aerospace and automotive industries to medicine and biotechnology. Such sensors often consist of indicator fluorophores in a polymeric...
Tracking Cotton Trash via Fluorescence
Aug 1, 2007 — Cotton producers are plagued with trash -- the bits of leaf, stem, hull, seed coat, bract and other unusable parts of the plant. Such debris determines cotton quality, and cleaner cotton is easier to process into materials such as yarn. Various...
White Light-Emitting Fluorophore Has Solid-State Applications
Jan 1, 2007 — White light emitted from displays is traditionally made by mixing red, green and blue light, but a novel class of fluorophores that radiate white light could one day provide another source, especially via LEDs. Robert M. Strongin and colleagues...
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April 2024
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