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Image Sensors and Modules for Endoscopy Applications: What Are the Latest Trends?
In recent years, endoscopes have evolved and now enable a range of minimally invasive diagnostic procedures and surgeries. The imaging function is now located in the small tip of the endoscope, where...
on demand
Advanced Packaging for Integrated Photonics: From Research to Manufacturing
Advanced packaging enables researchers to combine different technology platforms such as photonics, electronics, micro-electromechanical, and fluidics to address a vast array of exciting...
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Medical Laser Applications: Defining Measurement Solutions That Keep the Process on Track
As with any precision process, laser-based medical applications demand tight control of a laser’s behavior to keep the process on track. But how is this implemented in applications? Mark...
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Non-Invasive Glucose Monitoring Techniques using QCL-IR Lasers
There are 422 million people worldwide living with diabetes1, and current methods for monitoring blood glucose levels are painful, invasive, and can potentially require surgical procedures....
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PCR-Based Analysis of a Common Fluorescein Derivative Using Broadband Spectroscopy Platforms
PCR-based testing has rapidly increased in popularity and development since the start of the COVID-19 pandemic, and many new techniques are leveraging the latest performance advancements offered by...
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Fact or Fiction: Multidimensional Fluorescence Serves as a Reproducible Analytical Tool
Multidimensional fluorescence is a powerful spectroscopic approach to the analysis of complex mixtures. It tackles routine analytical problems that require sensitivity and selectivity that FT-IR,...
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Raman Spectroscopy for Forensic Science: Identification and Analysis of Biological Stains and Gunshot Residue
Raman spectroscopy has been known for decades as the most selective spectroscopic technique. Lednev and his team have developed and are commercializing the first universal method for the confirmatory...
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Soft Optical Systems as Biointegrated Technologies: From Biological Research to Clinical Health Care
Advanced optoelectronic systems that can intimately integrate with soft living tissues have the potential to accelerate progress in biological research and to serve as the foundations for new...
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Technical Advancements in Line-Field Confocal Optical Coherence Tomography for Improving the Management of Skin Cancer
Line-field confocal optical coherence tomography (LC-OCT) is an imaging technique based on a combination of reflectance confocal microscopy and time-domain OCT. It can generate cellular-resolution...
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Harnessing Photons for Bond-Selective Imaging, Neuromodulation, and the Killing of Superbugs
Chemical microscopy that utilizes fingerprint vibrational spectroscopic signals opens a new window to visualizing the orchestra of molecules and biological structures inside living systems. Ji-Xin...
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KEYNOTE: Raman Spectroscopy Provides Vital Analysis for Biomedical Research and Clinical Diagnostics
Especially in the fields of the life sciences and medicine, Raman-based technologies have proven their great potential, and they increasingly complement established methods such as fluorescence...
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Laser Microbiopsy Could Provide Detailed Pathological Data with Limited Sample Damage
While they are considered the gold standard for disease diagnosis, including cancer, tissue biopsy and histological evaluation have significant limitations. Among these limitations are a biopsy's...
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KEYNOTE: Specialized Laser Probes Capture Fluorescence Detail and Drive Diagnostics
Arrigoni discusses the various applications of lasers to biology and medicine, and categorizes them by the type of process involved and the most significant trends: Fluorescence (spectral) imaging by...
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Femtosecond Lasers Capture Key Diagnostic Details
Over the past 30 years, near-infrared, Ti:sapphire lasers have made a significant contribution toward our understanding of many key biological processes. The longer-wavelength lasers (>920 nm) can...
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Medical Laser Solutions
Modulight medical laser solutions are used widely in both diagnostic and therapeutic applications — in oncology, ophthalmology, genetics, and drug discovery and imaging. Modulight is a...
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Optical Technologies Are Poised to Guide Cancer Surgery in Low- to Middle-Income Regions
A majority of noncommunicable diseases — including almost all types of cancer — are treated with some sort of surgery. According to the World Health Organization (WHO), 4.8 billion people...
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BabyGlucoLight Uses Diffuse Optics to Link Glucose Levels at Birth with Early Brain Development
Very preterm newborns are more susceptible to changes in glucose levels (hypo- or hyperglycemia) during the first weeks postpartum. Achieving optimal glycemic control in this population is, however,...
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Computational 3D Microscopy with Optical Coherence Refraction Tomography
Through decades of technological development, optical coherence tomography (OCT) has become faster and more sensitive as a biomedical volumetric imaging modality. However, it still suffers from...
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Sub-Cellular Biology at Tissue Scales with Cleared Tissue Axially Swept Light-Sheet Microscopy
Large-scale interdisciplinary research efforts have worked to comprehensively catalog cellular architectures in health and disease. To aid in this effort, researchers have developed a scalable...
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Intraoperative OCT in Veterinary Surgery for Cancer
Surgery is a common cancer treatment for dogs and cats. Removing the complete tumor results in lower recurrence rates and improved survival rates. After surgery, the tumor is assessed for...
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Virtual Biomarkers: An Emerging High-Throughput Research Tool
Pathology underlies every facet of health care, influencing more than 70% of all medical decisions. It is used in every phase of pre-clinical and clinical drug development, in every tumor repository...
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Wavelength-Selective Optical Filters: Providing More Signal and Less Background to PCR Instruments
Engineers face many unique challenges when creating polymerase chain reaction (PCR) instrumentation. These challenges are seen in both the qualitative detection of nucleic acid sequences, using...
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Lasers in Dentistry: Past, Present, and Future
William Brown presents a history and future projection of lasers in dentistry, starting with the early wavelength research into laser applications for dental procedures. He also covers the current...
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Advancing Translational OCT to Assess Eardrum Dynamics and Middle Ear Infections
A middle ear infection is a prevalent pediatric disease caused by bacteria or viral pathogens in the middle ear. The infection is characterized by the presence of an accumulated fluid in a normally...
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Point-of-Care Functional Optical Spectroscopy Platform for Precision Quantification of In Vivo Tumor Metabolism and Vasculature in Small Animals
Caigang Zhu reports on a point-of-care optical spectroscopy platform and novel spectroscopic data processing techniques for simultaneous precision quantification of key metabolic and vascular...
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April 2024
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