Multimodal Functional OCT for Clinical Assessment of Oral Soft and Hard Tissue Conditions

Oct 25, 2022
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About This Webinar
Optical coherence tomography (OCT) is a noninvasive technique providing cross-sectional images of tissue microstructures and functional information with high resolution. Subhash reports on the development of an integrated multimodal functional OCT and angiographic imaging system with a light-induced autofluorescence (LIAF) imaging mode capable of providing anatomical, functional, and molecular imaging for in vivo clinical oral imaging applications. The OCT imaging is based on a high-speed, long-range vertical-cavity surface-emitting laser (VCSEL) source with linearized frequency, while the LIAF is based on a blue excitation light source (405nm) with an RGB digital camera and a 450-nm cut-on broadband optical filter. He demonstrates the clinical imaging feasibility of the system using an extraoral patient imaging interface and a compact hand-held intraoral imaging system for the assessment of various soft- and hard-tissue conditions, including caries, hypomineralization, dental biofilm, gingival tissue microstructural changes, and the visualization and quantification of gingival microvasculature.

***This presentation premiered during the 2022 BioPhotonics Conference. For more information on Photonics Media conferences, visit  

About the presenter
Hrebesh Molly SubhashHrebesh Molly Subhash is a senior principal scientist and technical lead with the Global Devices and Clinical Method Development Division of Colgate-Palmolive. He holds a doctorate in biomedical optics from Yamagata University in Japan and dual masters degrees in photonics technology and applied electronics from Cochin University of Science and Technology and Bharathiar University, respectively, both in India. Subhash has worked previously with the Spanish National Research Council and the Madrid-MIT M+Visión Consortium in Spain; the National Biophotoics and Imaging Platform Ireland in Galway, Ireland; Compact Imaging Inc. in Mountain View, Calif.; the Oregon Hearing Research Center in Portland, Ore.; the Oregon Health and Science University in Portland; the Human Sensing and Functional Sensor Engineering Lab in Yamagata, Japan; and the Raja Ramanna Centre for Advanced Technology in Indore, India. His research interests and expertise include biomedical optics, optical instrumentation, wearable sensors, and medical image and signal processing, particularly the development of cutting-edge and translational biophotonics technologies that interface and bridge basic engineering research and medical diagnosis and interventions.
ImagingBiophotonicsOCToptical coherence tomographytissue imaging
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