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Bio-Analytical Applications of Raman and the Role of Optical Filters

Apr 18, 2023
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Non-destructive, portable, and extremely discriminating in its analysis -- Raman spectroscopy has established itself as a powerful tool in the identification and quantification of chemicals in dock-to-stock analysis of pharmaceuticals, in-field and in-container identification of hazardous materials, and screening of liquids in airport security, among many other applications. Raman’s unique ability to distinguish molecular composition is starting to be applied in bio-analytical applications such as endoscopy, cancer detection, bone density, and other in vivo and in vitro biomedical applications.

However, Raman spectroscopy struggles with the elusive nature of Raman scattered signal photons from within the dominantly Rayleigh scattered source background. Typically less than one in a million photons exchange vibrational energy with the molecules under test and exhibit the associated Raman wavelength shift. To extract the Raman signal from the background, highly wavelength selective optical filters are necessary to provide more signal with less background to the detectors and enable the molecularly unique Raman fingerprint characteristics to be seen.

*** This presentation premiered during the 2023 Photonics Spectra Spectroscopy Conference. For more information on Photonics Media conferences, visit

About the presenter

Jason PalidwarJason Palidwar is the marketing manager for Iridian Spectral Technologies and has been with the company since 2006. He is also the product group manager of aerospace and specialty optics, focused on the optical filters used in satellite communications and Earth observation. He has over 20 years of experience working with thin-film optical filters. He has also developed filter specifications, together with Iridian’s customers, to optimize commercial needs in applications such as telecom, Raman spectroscopy, fluorescence microscopy, 3D entertainment, and IR remote sensing. Palidwar has a Master of Science degree in physics from McMaster University.
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