The TargetAmp 2-round biotin-aRNA amplification kit 3.0 from Epicentre Biotechnologies produces microgram amounts of biotin-aRNA (cRNA) from as little as 50 pg of total RNA, or about five cells. The linear amplification process preserves the relative transcript abundance of the sample and results in minimal, if any, nonspecific amplification products. The reaction can be performed in as little as two days. The kit is designed for use on Affymetrix GeneChip, Illumina Expression BeadChip and other microarray platforms.