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PI Physik Instrumente - Revolution In Photonics Align LW LB 3/24

Sharp Corners and Kaleidoscopes Lead to Novel Microscopy Techniques

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Hank Hogan

Researchers at Harvard Medical School in Boston have developed two microscopy techniques: a near-field method that offers potentially better performance than other superresolution techniques and a “mirror tunnel” approach that promises high-resolution, wide-field imaging. The first, dubbed differential near-field scanning optical microscopy, overcomes one of the problems with conventional aperture-based subwavelength imaging. The resolution of such methods is set by the aperture size, with smaller openings capable of imaging correspondingly smaller features. However, the signal and...Read full article

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    Published: January 2007
    Glossary
    nano
    An SI prefix meaning one billionth (10-9). Nano can also be used to indicate the study of atoms, molecules and other structures and particles on the nanometer scale. Nano-optics (also referred to as nanophotonics), for example, is the study of how light and light-matter interactions behave on the nanometer scale. See nanophotonics.
    photonics
    The technology of generating and harnessing light and other forms of radiant energy whose quantum unit is the photon. The science includes light emission, transmission, deflection, amplification and detection by optical components and instruments, lasers and other light sources, fiber optics, electro-optical instrumentation, related hardware and electronics, and sophisticated systems. The range of applications of photonics extends from energy generation to detection to communications and...
    superresolution
    Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
    FeaturesindustrialMicroscopymicroscopy techniquesmirror tunnelnanooptical microscopyphotonicsSensors & Detectorssuperresolution

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