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SERS detects DNA without labels

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Technique might be useful for drug discovery.

David L. Shenkenberg

DNA detection has revolutionized everything from forensics to diagnostic testing in medicine. Because most current detection methods are based on fluorescent labels that require costly and complex chemistry to implement, researchers at Rice University in Houston developed surface-enhanced Raman spectroscopy (SERS) for detecting DNA without labels. Using a mathematical spectral correlation function that they developed, the investigators quantitatively determined the reproducibility of their technique to detect single- and double-stranded DNA molecules of various lengths and sequences...Read full article

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    Published: June 2008
    Basic ScienceBiophotonicschemistrydiagnostic testingDNAMicroscopyResearch & TechnologySensors & Detectors

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