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Glowing Proteins See Cells

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BRONX, N.Y., Jan. 27, 2009 – New fluorescent proteins have been discovered that allow scientists to noninvasively visualize the structures and processes in living cells at the molecular level. Researchers at Gruss Lipper Biophotonics Center at Albert Einstein College of Medicine of Yeshiva University discovered the tools, which are photoactivatable fluorescent proteins (PAFPs) and other advanced fluorescent proteins (FPs). The fluorescent proteins now can follow cancer cells as they seek out blood vessels and spread throughout the body or can watch how cells manage intracellular debris, preventing premature...Read full article

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    Published: January 2009
    Glossary
    photonics
    The technology of generating and harnessing light and other forms of radiant energy whose quantum unit is the photon. The science includes light emission, transmission, deflection, amplification and detection by optical components and instruments, lasers and other light sources, fiber optics, electro-optical instrumentation, related hardware and electronics, and sophisticated systems. The range of applications of photonics extends from energy generation to detection to communications and...
    superresolution
    Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
    2008 Nobel Prize in ChemistryAlbert Einstein College of Medicine of Yeshiva UniversityAna Maria CuervoBasic ScienceBiophotonicsdigital camerasfluorescence microscopesfluorescent proteinsfluorescent timersgreen fluorescent proteingreen photonicsGruss Lipper Biophotonics Centerintracellular debrisLAMP-2Aliving cellsMicroscopyNews & Featuresoptical microscopyPAmCherry1photoactivatable fluorescent proteinsphotonicssuperresolutionVladislav VerkhushaLasers

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