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Copper-free chemistry facilitates in vivo imaging of biomolecules

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Gary Boas

Genetically encoded reporters provide dynamic imaging of proteins in live cells, but researchers increasingly are interested in biomolecules such as glycans and lipids that cannot be probed with the methods developed for proteins. Studies of both in vitro and static systems have not revealed much information about how these biomolecules behave in live cells. Researchers have described a technique that enables dynamic in vivo imaging of biomolecules that are not accessible with methods developed for imaging proteins. Shown here are carbohydrates in living cells 0, 15, 30, 45 and 60 min...Read full article

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    Published: December 2007
    Basic ScienceBiophotonicsdynamic imaginglive cellsMicroscopyNews & Featuresproteins

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