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Automatic tracking of single fluorophores

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Software algorithms for total internal reflection microscopy developed

Kevin Robinson

As they continue to further unravel the inner workings of cells, scientists are increasingly interested in the roles that proteins play in everything from regulating osmotic pressure in cells to excreting waste. Now, researchers at London’s MRC National Institute for Medical Research have developed a system for automatically detecting and tracking individual molecules that have been labeled with a fluorophore to better understand how they move in different environments and in different cells. The system involves two new computer algorithms for automatic detection and tracking. “The...Read full article

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    Published: March 2007
    biomolecular interactionsBiophotonicsdetectionenergyliving cellsMicroscopyResearch & Technologysingle molecules

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