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Deposition Sciences Inc. - Difficult Coatings - LB - 8/23

From fast-freeze to frame

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Caren B. Les, [email protected]

Researchers at Max Planck Institute of Biochemistry have obtained three-dimensional images of the vesicles and filaments involved in the communication among neurons in the brains of mammals. Using cryoelectron tomography, a microscopy technique based on the ultrafast freezing of cells, they acquired 3-D images of synapsis, the cellular structure in which the communication takes place. “I found particularly interesting that so little was known on the mechanisms of synaptic transmission, which is the basic process by which neurons communicate with each other and with muscle cells,...Read full article

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    Published: April 2010
    Glossary
    tomography
    Technique that defocuses activity from surrounding planes by means of the relative motions at the point of interest.
    3-D imageryBasic ScienceBiophotonicsBioScanbraincamerasCaren B. Lescellselectron cryotomograpyelectron microscopyenergyGermanyImagingMax Planck Institute of BiochemistryMicroscopyneuronsNewsOpticsRuben Fernandez-Busnadiegosynapsistomographyultrafast freezing

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