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New physical model reveals information on causes of cellular damage

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Research may lead to therapies for neurodegenerative disorders

Gary Boas

A variety of neurodegenerative disorders — including Alzheimer’s, Parkinson’s and Huntington’s diseases — have been linked to oxidative stress, in which free radicals chemically attack cells and parts of cells. Investigations of damage to the microtubule cytoskeletal proteins could reveal the mechanisms by which this occurs. But in vivo studies of these proteins are problematic at best because the many biomolecules necessary to cell survival tend to obscure these mechanisms. Several groups have probed microtubule dynamics in vitro, shedding light, for...Read full article

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    Published: June 2006
    BiophotonicsMicroscopyResearch & Technology

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