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Bright Boost for Fluorescent Probes

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PITTSBURGH, Aug. 26, 2010 – Researchers from Carnegie Mellon University’s Molecular Biosensor and Imaging Center (MBIC) are turning up the brightness on a group of fluorescent probes called fluoromodules that are used to monitor biological activities of individual proteins in real time. This latest advance enhances their fluoromodule technology by causing it to glow an order of magnitude brighter than typical fluorescent proteins. The new fluoromodules are five to seven times brighter than enhanced green fluorescent protein (EGFP), a development that is expected to open new avenues for research. In a paper...Read full article

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    Published: August 2010
    AmericasBasic ScienceBiophotonicsCarnegie Mellon Universitycell biologycell imagingCy3dyedronsEGFPenergyenhanced green fluorescent proteinFAPfluorescent probesfluorescent proteinsfluorogenfluorogen-activating proteinfluoromodulesImagingJournal of the American Chemical SocietyMarcel BruchezMBICMicroscopyMolecular Biosensor and Imaging CenterproteinsResearch & TechnologySensors & Detectors

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