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Advantages of Two-Photon Imaging

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Dr. James P. Smith

During the past decade, photon scanning tunneling microscopy has achieved resolution better than 100 nm, overcoming the optical diffraction limits. Recently, scientists at the State University of New York at Buffalo developed a two-photon system that has better signal-to-noise ratio and optical contrast than the one-photon microscopes. Photon scanning tunneling microscopy is an optical fluorescence method in which a laser excites one side of a thin sample while a fiber probe scans the opposite surface and collects the emitted photons. The aluminum-coated fiber probe has an apex diameter...Read full article

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    Published: April 2000
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