I hope to meet many of you at SPIE’s 2018 BiOS conference, which will be held January 27 and 28 in San Francisco’s Moscone Center. Like the rest of you, I’ll be going to presentations and walking the exhibition floor. I’ll also be at the Photonics Media booth — number 8735 — for a Meet the Editor event from 3 to 4 p.m., Saturday, January 27. Please stop by to say hello, talk about your research or suggest what you’d like to see in the magazine. Three days later, at 3 to 4 p.m., Tuesday, January 30, at Photonics West, which immediately follows BiOS, there will be a second Meet the Editors. I will be joined at the Photonics Media Booth — number 846-847 — by Michael Wheeler, editor of Photonics Spectra; Justine Murphy, editor of EuroPhotonics; Autum Pylant, Photonics Media news editor; and Karen Newman, publisher of our book division, Photonics Media Press. At Photonics Media, we’ve been hard at work on the materials we will take to San Francisco, which includes copies of this magazine. Two articles this month look at striking advances in microscopy. Our cover story introduces MUSE (microscopy with UV surface excitation), a technique that can greatly speed up the process of diagnosing cancer. MUSE takes advantage of the limited penetration depth of deep UV light to provide an optical alternative to the arduous task of physical sectioning. Developed at UC Davis, MUSE also opens the way for allowing diagnosis in low-resource settings. “MUSE: Simple Slide-Free Microscopy,” by Farzad Fereidouni, Austin Todd and Richard Levenson, (read article). Silicone immersion objectives, the subject of the second microscopy story, provide valuable new tools for researchers. Because silicone has a greater refractive index than water or oil, it enables the acquisition of brighter and higher-resolution 3D images of live cells and tissue. Objectives made from it are useful to developmental biology, regenerative biology and neurobiology, writes Andrew Samuelsson of Olympus Corp. “Silicone Immersion Objectives Boost 3D Live-Cell Imaging” (read article). Elsewhere in the magazine: • Jürgen Popp, Iwan Shie and Aleksandar Lukic of the Leibniz Institute discuss their work with in vivo endospectroscopic imaging for delineating tumor margins and determining tumor type and grade. Extending microspectroscopy to in vivo imaging requires optical fiber probes that can access difficult-to-reach body regions. Besides miniaturization, this requires innovative scanning and robust and alignment-free light sources. “Endospectroscopic Imaging Takes Optical Biopsies to the Next Level” (read article). • Contributing Editor Marie Freebody reviews advancements in terahertz imaging for biomedical applications. Terahertz radiation can produce strikingly clear images, but it has difficulty penetrating substances with a high water content. Some research exploits this sensitivity: Skin cancer tissues, for example, have different water content than healthy skin. Other research seeks to boost image resolution. “Terahertz Imaging Takes Aim at Dermatology and Dentistry” (read article). • Our Biopinion is written by Sujatha Ramanujan, managing director of Luminate, an accelerator for optics, photonics and imaging companies. Ramanujan urges the industry to do more to assist emerging businesses and talks about three biomedical innovators who are participating this year in Luminate’s six-month program. “Emerging companies deserve our support,” (read article). • For our special section, Senior Editor Justine Murphy previews the 2018 BiOS conference (read article). Enjoy the issue.