Request InfoLeica Microsystems GmbHLeica Microsystems GmbH has released the FCM1000 imaging solution for real-time in vivo and in situ imaging of fluorescence in mice and rats. A fibered microendoscope, it enables users to image deep-brain events, peripheral nerves and angiogenesis with cellular resolution and in a minimally invasive manner. It operates at 12 fps and offers an intuitive user interface designed to simplify instrument setup, image acquisition and data analysis.See full productRelated content from Photonics MediaPRODUCTSPromoted Content April 2024 IssueGet More Data: Automate Your MicroscopeZaber offers a selection of standard and customized motorized microscope stage products. They offer: Exceptional Performance Maximize your throughput and consistency with up to 500-nm...BioPhotonics.com March 2024 Issue380-nm Laser ModuleThe IQ1C195(380-210) from Power Technology is a continuous wave high-power 380-nm laser diode module for high-end analytical and scientific applications, such as bioanalysis, fluorescence, and Raman...Promoted Content November 2023 IssueNucleus™ Automated MicroscopesThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...Promoted Content March 2024 IssueUltra-Precision Microscopy DemoThe Nucleus™ microscopy platform provides a complete set of interchangeable hardware modules and software tools, making it ideal for OEMs and lab managers engaged in fluorescence cellular...ARTICLESPhotonics Spectra April 2023 IssueSignal Enhancement Enables Study of Label-Free ProteinsResearchers at Institut Fresnel have developed a technique to detect the ultraviolet-autofluorescence signal in single proteins, opening the way for the label-free study of thousands of proteins...Photonics.com 9/16/2022TOPTICA Relocates North American HQ: Week in Brief: 09/16/2022TOPTICA Photonics Inc. moved its U.S. headquarters to Pittsford, N.Y. The company’s headquarters had been in Farmington, N.Y., and the new location remains near Rochester, N.Y. According to the...Photonics Spectra May 2024 IssueMemory Element Enhances a Human Sight-Mimicking Quantum SystemCollaborating researchers from Hong Kong, China, and Germany have developed a quantum-sensing technology that encodes changes in fluorescence intensity into spikes that occur during optically...BioPhotonics Jan/Feb 2023 IssueNobel Prize-Winning Techniques Help Resolve Imaging ChallengeUsing a technique that was recently awarded the 2022 Nobel Prize in chemistry, researchers at Cornell University used expansion microscopy to study lipids, the water-repellent, dynamic components...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookDetectors: Guideposts on the Road to SelectionAny number of medical, industrial, and analytical applications requires the detection of light. Chemiluminescence, bioluminescence, fluorescence, and atomic absorption are just a few, and all require...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookLasers: Understanding the BasicsOver 60 years have passed since the first demonstration of a laser in 1960. After the initial spark of interest, lasers were for a while categorized as “a solution waiting for a problem,”...WHITEPAPERSPhotonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 2/28/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.Photonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...Photonics.com 1/10/2024Laser Light Engine Output StabilityIn this white paper, Dr. Iain Johnson, Lumencor’s Director of Technical Support, tests Lumencor’s laser-based CELESTA Light Engine for consistency, power, and stability using continuous wave...WEBINARSPhotonics.com 12/14/2023Image Sensors and Modules for Endoscopy Applications: What Are the Latest Trends?In recent years, endoscopes have evolved and now enable a range of minimally invasive diagnostic procedures and surgeries. The imaging function is now located in the small tip of the endoscope, where...Photonics.com 10/25/2022Semantic and Instance Segmentation of Microscopic Images Using Pretrained Neural NetworksRobust segmentation of microscopic images is the foundation for the subsequent analysis of the image content and hence the (biological) properties of the sample. In addition to semantic segmentation,...Photonics.com 10/25/2022BioPhotonics Conference 2022: October 25-27The publishers of BioPhotonics invite you to hear from the world’s top experts in microscopy, spectroscopy, OCT, photoacoustic imaging, flow cytometry, biomedical imaging, and medical laser...Photonics.com 10/24/2023Multimodal Multiphoton Imaging in Life Sciences ExplorationHigh-quality imaging of samples in 3D and 4D, as well as label-free and non-destructive imaging of unique biomarkers, is becoming more important in understanding cellular mechanisms and their...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionarytwo-photon excited fluorescenceTwo-photon excited fluorescence (TPEF) is a nonlinear optical method that allows imaging of biological cells and living tissue. The advantage of TPEF in comparison to conventional fluorescence...Photonics Dictionarysingle-walled carbon nanotubesReferred to as SWCNTs, these cylindrical nanostructures composed of a folded sheet of graphene can be used as near-infrared markers for small animal multiplex imaging. Emitting at different...Photonics Dictionarymedical lasersMedical lasers are devices that produce intense beams of light with specific characteristics and properties, which are used for various medical applications. These lasers emit light in the form of...Photonics Dictionarylight sheet fluorescence microscopyAlso known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...VIDEOSPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 1/9/2024CELESTA Light Engine - Customer Success StorySolving MERFISH challenges for Spatial TranscriptomicsPhotonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...PHOTONICS BUYERS' GUIDE CATEGORIESFluorescent Light SourcesA fluorescent light source is a tube containing mercury vapor and lined with a phosphor. When current is passed through the vapor the strong ultraviolet emission excites the phosphor, which emits...Fluorescence Imaging SystemsFluorescence MicroscopesPhotometersA photometer is a device used to compare the luminous intensities of two sources by comparing the illuminance they produce.COMPANIESPhotonics Buyers' GuideAvantes BVAvantes has spent the last 30 years refining its mission as a trusted and innovative optical instruments and solutions source. Focused on applications and measurements, Avantes offers Spectrometers,...Photonics Buyers' GuideAvantier Inc.Avantier Inc. is an unparalleled leader in providing innovative imaging systems solutions and optical systems solutions. We offer advance precision custom optical design, optical engineering...Photonics Buyers' GuideEdinburgh Instruments Ltd.Founded in 1971, Edinburgh Instruments Ltd. is a global provider of sophisticated, state-of-the-art analytical instrumentation for optical spectroscopy. We design and manufacture a range of...Photonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...