Request InfoLeica Microsystems GmbHWETZLAR, Germany, May 27, 2010 — Resolution and contrast are crucially important for fluorescence applications in wide-field microscopy. Undesired haze effects that reduce contrast can be minimized by using the smart principle of structured illumination, which results in fluorescence images with good contrast, high axial resolution and ultrasharp 2-D sections of the specimen. Intelligent Structured Illumination Microscopy from Leica Microsystems uses the proven OptiGrid technique. Working in harmony with the company’s high-quality optics, the aperture diaphragm integrated with the fluorescence light path also...See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Sep/Oct 2023 IssueAI-Powered Microscope SoftwareLeica Microsystems’ Aivia 12 software provides AI-powered image analysis. It incorporates the Cellpose deep learning model to tackle dense neuron images, improving soma detection by as much as...Photonics.com 1/31/20243D Surgical MicroscopeThe ARveo 8 from Leica Microsystems is a digital visualization microscope for neurosurgery applications. Making use of a 3D view and AR fluorescence, the microscope helps surgeons by creating clear...BioPhotonics Mar/Apr 2024 IssueOphthalmic MicroscopeThe Proveo 8 from Leica Microsystems is an ophthalmic microscope with an integrated EnFocus intraoperative OCT. The integration results in a 40% reduction in stack height — from 60 to 36 mm....Photonics.com 6/12/2023Surface Analysis SoftwareThe Mountains® 10 surface metrology and microscopy analysis software from Digital Surf introduces new features and tools to enhance analysis capabilities. The MountainsImage® product...ARTICLESPhotonics.com 2/5/2024High-Throughput Imaging Reveals Multi-Particle Cellular ActivityA new software program can map the movements of multiple particles within cells simultaneously, providing insight into cellular functions that are difficult — and sometimes impossible —...Photonics.com 4/7/2023Ams OSRAM Wraps Digital Systems Business Divestiture: Week in Brief: 04/07/23Electro Optic Systems (EOS) secured a conditional contract to supply remote weapon systems (RWS) to Ukraine valued at up to $80 million. EOS’ Defence Systems business secured the contract with...Photonics Spectra February 2024 IssueAlgorithm Boosts Live-Cell Imaging's CapabilitiesSuperresolution radial fluctuations (SRRF), a superresolution algorithm, works by observing fluctuations in radial symmetry throughout the frames of an image. SRRF supports live-cell, superresolution...Photonics.com 2/23/2024SPAD Elevates Spatiotemporal Resolution in Conventional MicroscopesImage scanning microscopy (ISM), a superresolution technique enabled by the advent of fast and compact detector arrays, provides signal-to-noise ratio (SNR), optical sectioning, and spatial...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookOptical Design Software: Fundamentals and PotentialOptical design software allows the user to develop a configuration of optical elements that manipulate the trajectory of light for the purposes of creating an image, illuminating a target, coupling...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...WHITEPAPERSPhotonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 2/21/2024Dual Inverted Selective Plane Illumination MicroscopeAn overview of diSPIMPhotonics.com 2/28/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.WEBINARSPhotonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...Photonics.com 6/6/2024COTS to Custom: Using Microscope Objectives in OEM ProductsDavid Biss of Optikos navigates the trade-offs that must be considered when developing the architecture of a microscope. In the vast expanse of life sciences, designing an OEM microscopy platform...Photonics.com 6/11/2015Biophotonic Imaging for Medicine: A Digital ConferenceResearchers from around the world presented their latest work at “Biophotonic Imaging for Medicine: A Digital Conference.” Presentations focused on a range of light-based imaging and...Photonics.com 6/30/2021European Photonics Manufacturing Services Funded by ECThis event is supported by the European initiatives presented and is moderated by EPIC, the European Photonics Industry Consortium. The European Commission is helping companies access the...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryultraviolet fiber opticsUltraviolet (UV) fiber optics refers to optical fibers that are designed and optimized for the transmission of ultraviolet light, which is electromagnetic radiation with wavelengths shorter than...Photonics Dictionarylong-pass filterA long-pass filter is an optical filter that allows longer wavelengths of light to pass through while blocking or attenuating shorter wavelengths. These filters are designed to transmit light with a...Photonics Dictionaryerecting systemLenses or prisms that serve to erect the image; i.e., to bring the image upright after it has been inverted by the objective.Photonics DictionaryPorro prism erecting systemThe arrangement of two Porro prisms so that the inverted image formed by certain types of optical instruments is the same as the object. The first prism, which is set at 90° to the second, inverts...VIDEOSPhotonics.com 8/24/2022Ramacle® Software Highlight: Fast Mapping - Edinburgh InstrumentsThis Software Highlight focuses on Fast Mapping in our Ramacle software. Fast Mapping enables the user to acquire Raman maps with significantly reduced acquisition times via more efficient stage...Photonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 2/21/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 4/19/2022Fluorescence Filter Images - Optolong Optics Co. Ltd.Optolong Optics Co. Ltd., brand owner of Optolong, is a manufacturer of fluorescence filters and astronomy filters. We also offer other interference filters including UV filters, visible filters, and...PHOTONICS BUYERS' GUIDE CATEGORIESResearch MicroscopesElectronic Design Automation SoftwareUltraviolet MicroscopesAn ultraviolet microscope is a microscope used either to detect selective absorption of various wavelengths by the specimen or to achieve increased resolution by virtue of the short wavelength of...Ultraviolet MirrorsCOMPANIESPhotonics Buyers' GuideFOCtek Photonics Inc.FOCtek provides customers with all types of custom manufactured lenses, Precision Optical Components, Polarizing Optics, Prisms, Filters, Coatings, Optical Systems, Crystals, Nonlinear Crystals,...Photonics Buyers' GuideOhara CorporationOHARA manufactures more than 130 environmentally safe optical glass types, free of both lead and arsenic. More than 300 tons of optical glass are melted per month, available in the following forms of...Photonics Buyers' GuideLaCroix Precision OpticsThe LaCroix name is synonymous with quality precision optics. Since 1947, three generations of family leadership have guided LaCroix Precision Optics to become the premier precision optics...Photonics Buyers' GuideGlass Fab Inc.A History of Quality Since 1974 Glass Fab Inc. has met customers' stringent specifications by providing fabricated parts made of optical glass, filter glass, fused quartz and fused silica, low...